Patents by Inventor Jeff Wade HILL

Jeff Wade HILL has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • CXCR antagonistic peptides and uses thereof
    Patent number: 10548942
    Abstract: The present invention provides a novel class of medicament based on CXCR antagonistic peptides. Among other things, the present invention provides peptides, compositions and methods for treating diseases, disorders and conditions in which a CXCR mediated pathway is implicated. Compositions and methods for effective treatment of inflammation, stroke, traumatic brain injury, pancreatic cancer, and others are provided.
    Type: Grant
    Filed: April 25, 2018
    Date of Patent: February 4, 2020
    Assignee: STC.UNM
    Inventor: Jeff Wade Hill
  • TREATMENT AND PREVENTION OF STROKE AND OTHER NEUROLOGICAL DISORDERS
    Publication number: 20190133975
    Abstract: Using high-throughput screening, in an oxygen-glucose deprivation (OGD) model, isoxsuprine hydrochloride was identified as a potent neuroprotective compound. In an animal middle artery occlusion (MCAO) model of transient focal ischemia, isoxsuprine significantly reduced infarct volume compared to vehicle. The invention, therefore, provides methods of treatment and pharmaceutical compositions that are useful in the treatment and prevention of a wide-variety of ischemia-related injuries, including stroke.
    Type: Application
    Filed: January 8, 2019
    Publication date: May 9, 2019
    Inventor: Jeff Wade Hill
  • Treatment and prevention of stroke and other neurological disorders
    Patent number: 10220008
    Abstract: Using high-throughput screening, in an oxygen-glucose deprivation (OGD) model, isoxsuprine hydrochloride was identified as a potent neuroprotective compound. In an animal middle artery occlusion (MCAO) model of transient focal ischemia, isoxsuprine significantly reduced infarct volume compared to vehicle. The invention, therefore, provides methods of treatment and pharmaceutical compositions that are useful in the treatment and prevention of a wide-variety of ischemia-related injuries, including stroke.
    Type: Grant
    Filed: August 14, 2014
    Date of Patent: March 5, 2019
    Assignee: STC.UNM
    Inventor: Jeff Wade Hill
  • CXCR ANTAGONISTIC PEPTIDES AND USES THEREOF
    Publication number: 20180311302
    Abstract: The present invention provides a novel class of medicament based on CXCR antagonistic peptides. Among other things, the present invention provides peptides, compositions and methods for treating diseases, disorders and conditions in which a CXCR mediated pathway is implicated. Compositions and methods for effective treatment of inflammation, stroke, traumatic brain injury, pancreatic cancer, and others are provided.
    Type: Application
    Filed: April 25, 2018
    Publication date: November 1, 2018
    Applicant: STC.UNM
    Inventor: Jeff Wade Hill
  • CXCR antagonistic peptides and uses thereof
    Patent number: 9981003
    Abstract: The present invention provides a novel class of medicament based on CXCR antagonistic peptides. Among other things, the present invention provides peptides, compositions and methods for treating diseases, disorders and conditions in which a CXCR mediated pathway is implicated. Compositions and methods for effective treatment of inflammation, stroke, traumatic brain injury, pancreatic cancer, and others are provided.
    Type: Grant
    Filed: November 25, 2014
    Date of Patent: May 29, 2018
    Assignee: STC.UNM
    Inventor: Jeff Wade Hill
  • CXCR ANTAGONISTIC PEPTIDES AND USES THEREOF
    Publication number: 20160296588
    Abstract: The present invention provides a novel class of medicament based on CXCR antagonistic peptides. Among other things, the present invention provides peptides, compositions and methods for treating diseases, disorders and conditions in which a CXCR mediated pathway is implicated. Compositions and methods for effective treatment of inflammation, stroke, traumatic brain injury, pancreatic cancer, and others are provided.
    Type: Application
    Filed: November 25, 2014
    Publication date: October 13, 2016
    Inventor: Jeff Wade Hill
  • TREATMENT AND PREVENTION OF STROKE AND OTHER NEUROLOGICAL DISORDERS
    Publication number: 20160193161
    Abstract: Using high-throughput screening, in an oxygen-glucose deprivation (OGD) model, isoxsuprine hydrochloride was identified as a potent neuroprotective compound. In an animal middle artery occlusion (MCAO) model of transient focal ischemia, isoxsuprine significantly reduced infarct volume compared to vehicle. The invention, therefore, provides methods of treatment and pharmaceutical compositions that are useful in the treatment and prevention of a wide-variety of ischemia-related injuries, including stroke.
    Type: Application
    Filed: August 14, 2014
    Publication date: July 7, 2016
    Inventor: Jeff Wade HILL