Patents by Inventor Jeff Wegener

Jeff Wegener has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • Polymerase enzymes and reagents for enhanced nucleic acid sequencing
    Publication number: 20080108082
    Abstract: Compositions that include DNA polymerases having increased residence times for nucleotide analogues, particularly modified recombinant ?29-type DNA polymerases with such increased residence times, are provided. Methods of making the polymerases and of using the polymerases in sequencing and DNA amplification are also provided. Compositions including ?-thiophosphate nucleotide analogues with four or more phosphate groups are described, as are methods for determining the sequence of nucleic acid molecules using such analogues.
    Type: Application
    Filed: October 22, 2007
    Publication date: May 8, 2008
    Applicant: Pacific Biosciences of California, Inc.
    Inventors: David Rank, Arek Bibillo, David Hanzel, Paul Peluso, Jeff Wegener