Patents by Inventor Jefferson Y. Chan

Jefferson Y. Chan has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • Methods for preventing induced synthesis of proteasomes in human cells
    Patent number: 9493833
    Abstract: Methods and compositions for inhibiting Nrf1 activity are provided for enhancing apoptosis in mammalian cells. Apoptosis is enhanced in mammalian cells by co-inhibiting Nrf1 activity and proteasome activity. Methods for identifying Nrf1 inhibitors are provided using an assay for screening Nrf1 inhibitors that enhance proteasome inhibition by preventing induced proteasome expression.
    Type: Grant
    Filed: November 8, 2010
    Date of Patent: November 15, 2016
    Assignees: THE REGENTS OF THE UNIVERSITY OF CALIFORNIA, CALIFORNIA INSTITUTE OF TECHNOLOGY
    Inventors: Raymond J. Deshaies, Senthil Radhakrishnan, Candy S. Lee, Jefferson Y. Chan