Abstract: Novel formulations are disclosed of a therapeutically effrective composition comprising two or more of an extract of Ganoderma lucidum, an extract of Salvia miltiorrhiza, an extract of Scutellaria barbata, and an extract of Scutellaria baicalensis wherein each extract comprises about 1 to about 90 percent by weight. Extracts are made in aqueous solvents, alcohol solvents and non-alcoholic organic solvents. Formulations comprising one or more emulsifiers demonstrating higher bioavailablity and maximum tolerated dose are provided.

Abstract: Methods for using botanical compositions comprising administration of non-alcoholic organic extracts of Ganoderma lucidum, Salvia miltiorrhiza, and Scutellaria barbata in conjunction with docetaxel for cancer therapy, are provided. Method for treatment or therapy of prostate cancer in a human is provided, the method comprising: administering an effective amount of the botanical composition during a period of administering concurrently an effective amount of docetaxel, wherein the concurrent administration of the docetaxel and the botanical composition achieves a therapeutic effect that is more effective than either agent alone.