Patents by Inventor Jeffery Dove

Jeffery Dove has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • Capping bioprosthetic tissue to reduce calcification
    Patent number: 8357387
    Abstract: A treatment for bioprosthetic tissue used in implants or for assembled bioprosthetic heart valves to reduce in vivo calcification. The method includes applying a calcification mitigant such as a capping agent or an antioxidant to the tissue to specifically inhibit oxidation in tissue. Also, the method can be used to inhibit oxidation in dehydrated tissue. The capping agent suppresses the formation of binding sites in the tissue that are exposed or generated by the oxidation and otherwise would, upon implant, attract calcium, phosphate, immunogenic factors, or other precursors to calcification. In one method, tissue leaflets in assembled bioprosthetic heart valves are pretreated with an aldehyde capping agent prior to dehydration and sterilization.
    Type: Grant
    Filed: December 18, 2008
    Date of Patent: January 22, 2013
    Assignee: Edwards Lifesciences Corporation
    Inventors: Jeffery Dove, Darin Dobler, Jim Davidson, Gregory A. Wright
  • Capping bioprosthetic tissue to reduce calcification
    Patent number: 7972376
    Abstract: A treatment for bioprosthetic tissue used in implants or for assembled bioprosthetic heart valves to reduce in vivo calcification. The method includes applying a calcification mitigant such as a capping agent or an antioxidant to the tissue to specifically inhibit oxidation in tissue. Also, the method can be used to inhibit oxidation in dehydrated tissue. The capping agent suppresses the formation of binding sites in the tissue that are exposed or generated by the oxidation and otherwise would, upon implant, attract calcium, phosphate, immunogenic factors, or other precursors to calcification. In one method, tissue leaflets in assembled bioprosthetic heart valves are pretreated with an aldehyde capping agent prior to dehydration and sterilization.
    Type: Grant
    Filed: May 11, 2010
    Date of Patent: July 5, 2011
    Assignee: Edwards Lifesciences Corporation
    Inventors: Jeffery Dove, Darin Dobler, Jim Davidson, Gregory Wright
  • Capping Bioprosthetic Tissue to Reduce Calcification
    Publication number: 20090164005
    Abstract: A treatment for bioprosthetic tissue used in implants or for assembled bioprosthetic heart valves to reduce in vivo calcification. The method includes applying a calcification mitigant such as a capping agent or an antioxidant to the tissue to specifically inhibit oxidation in tissue. Also, the method can be used to inhibit oxidation in dehydrated tissue. The capping agent suppresses the formation of binding sites in the tissue that are exposed or generated by the oxidation and otherwise would, upon implant, attract calcium, phosphate, immunogenic factors, or other precursors to calcification. In one method, tissue leaflets in assembled bioprosthetic heart valves are pretreated with an aldehyde capping agent prior to dehydration and sterilization.
    Type: Application
    Filed: December 18, 2008
    Publication date: June 25, 2009
    Applicant: EDWARDS LIFESCIENCES CORPORATION
    Inventors: Jeffery Dove, Darin Dobler, Jim Davidson, Gregory A. Wright