Patents by Inventor Jeffery K. Taubenberger

Jeffery K. Taubenberger has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • Synthetic catalase/superoxide dismutase mimetics and methods for treating viral infections
    Patent number: 10683316
    Abstract: The invention provides for the treatment of disorders related to viral infection, using salen manganese compounds.
    Type: Grant
    Filed: November 9, 2012
    Date of Patent: June 16, 2020
    Assignees: The United States of America, as represented by the Secretary, Department of Health and Human Services, Trustees of Boston University
    Inventors: John C. Kash, Jeffery K. Taubenberger, Rodney L. Levine, Susan Doctrow
  • Polyvalent influenza virus-like particles (VLPS) and use as vaccines
    Patent number: 10130700
    Abstract: This disclosure provides compositions that include a mixture of viral like particles (VLPs), expressing different individual influenza hemagglutinin (HA) proteins that elicit broadly reactive immune responses to a wide variety of influenza viruses. For example, the composition can include at least two different influenza VLPs, a first VLP comprising a first HA polypeptide and a second VLP comprising a second influenza HA polypeptide, wherein the first and the second HA polypeptide are different subtypes and/or are from different influenza viruses, and a pharmaceutically acceptable carrier and/or an adjuvant. Methods of using the disclosed polymeric influenza VLP compositions to stimulate an immune response against influenza viruses, for example as a pre-pandemic or a seasonal vaccine, are provided.
    Type: Grant
    Filed: May 8, 2015
    Date of Patent: November 20, 2018
    Assignee: The United States of America, as represented by the Secretary, DHHS
    Inventor: Jeffery K. Taubenberger
  • POLYVALENT INFLUENZA VIRUS-LIKE PARTICLES (VLPS) AND USE AS VACCINES
    Publication number: 20170128562
    Abstract: This disclosure provides compositions that include a mixture of viral like particles (VLPs), expressing different individual influenza hemagglutinin (HA) proteins that elicit broadly reactive immune responses to a wide variety of influenza viruses. For example, the composition can include at least two different influenza VLPs, a first VLP comprising a first HA polypeptide and a second VLP comprising a second influenza HA polypeptide, wherein the first and the second HA polypeptide are different subtypes and/or are from different influenza viruses, and a pharmaceutically acceptable carrier and/or an adjuvant. Methods of using the disclosed polymeric influenza VLP compositions to stimulate an immune response against influenza viruses, for example as a pre-pandemic or a seasonal vaccine, are provided.
    Type: Application
    Filed: May 8, 2015
    Publication date: May 11, 2017
    Applicant: THE UNITED STATES OF AMERICA, as represented by the Secretary, Department of Health and Human Serv
    Inventor: Jeffery K. Taubenberger
  • SYNTHETIC CATALASE/SUPEROXIDE DISMUTASE MIMETICS AND METHODS FOR TREATING VIRAL INFECTIONS
    Publication number: 20140329792
    Abstract: The invention provides for the treatment of disorders related to viral infection, using salen manganese compounds.
    Type: Application
    Filed: November 9, 2012
    Publication date: November 6, 2014
    Inventors: John C. Kash, Jeffery K. Taubenberger, Rodney L. Levine, Susan Doctrow