Abstract: Selected compounds are effective for prophylaxis and treatment of diseases, such as angiogenesis mediated diseases. The invention encompasses novel compounds, analogs, prodrugs and pharmaceutically acceptable salts thereof, pharmaceutical compositions and methods for prophylaxis and treatment of diseases and other maladies or conditions involving, cancer and the like. The subject invention also relates to processes for making such compounds as well as to intermediates useful in such processes.

Abstract: A head gasket assembly is provided comprising a solid non-compressible or rigid gasket body comprising a plurality of apertures for engine coolant, oil and combustion chambers. The gasket body has grooves formed therein for retaining and controlling the compression of elastomeric seals used for sealing engine coolant and oil apertures. The gasket body is then fitted or accompanied by a combustion seal. The combustion seals are specifically designed for the particular engine application, based on temperature, pressure and other operating characteristics. This assembly allows a direct fit with standard engine technology and requires no machining of heads, blocks, or cylinder liners. The result is a gasket body that precisely controls the compression on the seals, which improves engine performance without any machining of the engine while carrying highly elastic compounds to seal coolant and oil.

Abstract: A method and system for speculatively pre-fetching data from a memory. A memory controller on a data bus “snoops” data requests put on the data bus by a bus control logic. Based on information in the header of the data request, such as transaction type, tag, transaction size, etc., a speculative pre-fetch is made to read data from the memory associated with the memory controller. If the speculative fetch turns out to be correct, then the memory controller makes an assumption that the pre-fetch was too conservative (non-speculative), and a pre-fetch for a next data request is performed at an earlier more speculative time. If the speculative fetch turns out to be incorrect, then the memory controller makes an assumption that the pre-fetch was too speculative (made early), and a pre-fetch for a next data request is performed at a later less speculative time.

Abstract: An improved method and apparatus for selecting invalid members as victims in a least recently used cache system. An invalid cache line selection unit has an input connected to a cache directory and an output connected to a most recently used update logic. In response to a miss in the cache, an invalid cache line is identified from information in the cache directory by the invalid cache line selection unit. This invalid cache line is updated to be the next victim by the most recently used update logic, rather than attempting to override the current victim selection by a least recently used victim selection logic. The next victim also may be selected in response to a cache hit in which information from the cache directory also is read.

Abstract: Selected amines are effective for prophylaxis and treatment of diseases, such as angiogenesis mediated diseases. The invention encompasses novel compounds, analogs, prodrugs and pharmaceutically acceptable salts thereof, pharmaceutical compositions and methods for prophylaxis and treatment of diseases and other maladies or conditions involving, cancer and the like. The subject invention also relates to processes for making such compounds as well as to intermediates useful in such processes.

Abstract: Selected amines are effective for prophylaxis and treatment of diseases, such as angiogenesis mediated diseases. The invention encompasses novel compounds, analogs, prodrugs and pharmaceutically acceptable salts thereof, pharmaceutical compositions and methods for prophylaxis and treatment of diseases and other maladies or conditions involving, cancer and the like. The subject invention also relates to processes for making such compounds as well as to intermediates useful in such processes.

Abstract: Selected heterocyclic compounds are effective for prophylaxis and treatment of diseases, such as angiogenesis mediated diseases. The invention encompasses novel compounds, analogs, prodrugs and pharmaceutically acceptable derivatives thereof, pharmaceutical compositions and methods for prophylaxis and treatment of diseases and other maladies or conditions involving, cancer and the like. The subject invention also relates to processes for making such compounds as well as to intermediates useful in such processes.

Abstract: For each small image region (in space and time), a measure of perceptual transparence of each of a set of possible watermark carrier modulations is used to choose a subset of such modulations, from which a secure random number generator selects, for each image region, a single carrier, modulations of which carry the watermark data.

Abstract: A system and method for reducing resource collisions associated with memory units. Resource collisions may be reduced in part by a hash that combines the number N bits in the bank selector field with the number M bits adjacent to a region of correlation, e.g., row selector field, in an address to determine which bank in a memory unit, e.g., cache, may store the information associated with the address.

Abstract: Systems and methods of utilizing communications networks and multivariate analysis to predict or recommend optimal products from a predefined population of commercially available products are disclosed. The recommendations are based on intelligence contained in processing elements and subjective and/or objective product information received from consumers or input to the systems as part of their initial setup. The output of the systems comprise sets of products that they predict the consumer will prefer and/or perform well for the problem or concern identified by the consumer. The performance and preference predictions are a function of consumer problems and product responsiveness patterns. Objective product information is generally obtained with diagnostic instruments. Data measured with the diagnostic instruments may be communicated to the data processing portions of the invention via the Internet.

Abstract: A system and method for reducing resource collisions associated with memory units. Resource collisions may be reduced in part by a hash that combines the number N bits in the bank selector field with the number M bits adjacent to a region of correlation, e.g., row selector field, in an address to determine which bank in a memory unit, e.g., cache, may store the information associated with the address.

Abstract: A self-extinguishing torch for use in theatrical environments includes a supporting basket having a support for torch fuel. The supporting basket includes a screen providing side ventilation for containing torch fuel on the support and admitting air through the side ventilation to burn torch fuel. The supporting basket has fuel, which provides torch lighting. A container having an opening for receiving, surrounding, and containing the supporting basket has a handhold remote from the container for permitting the container to be held by a hand. A normally closed top is provided for moving from an open position to a closed position over the container with the supporting basket therein. The normally closed top is biased to the open position when the supporting basket protrudes from the container at the normally closed top.

Abstract: Compounds which are useful as inhibitors of cholesterol biosynthesis and thus as hypocholesterolemic agents are provided which have a quinoline or a pyridine anchor attached by means of a linker to a binding domain sidechain, which compounds inhibit the enzyme 3-hydroxy-3-methyl-glutaryl-coenzyme A reductase.

Abstract: Compounds which are useful as inhibitors of cholesterol biosynthesis and thus as hypocholesterolemic agents are provided which have a quinoline or a pyridine anchor attached by means of a linker to a binding domain sidechain, which compounds inhibit the enzyme 3-hydroxy-3-methyl-glutaryl-coenzyme A reductase.