Patents by Inventor Jeffrey A. Deskus

Jeffrey A. Deskus has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • PYRIDIN-3-YL ACETIC ACID DERIVATIVES AS INHIBITORS OF HUMAN IMMUNODEFICIENCY VIRUS REPLICATION
    Publication number: 20200055839
    Abstract: Disclosed are compounds of Formula I, including pharmaceutically acceptable salts, pharmaceutical compositions comprising the compounds, methods for making the compounds and their use in inhibiting HIV integrase and treating those infected with HIV or AIDS.
    Type: Application
    Filed: January 2, 2018
    Publication date: February 20, 2020
    Inventors: Makonen BELEMA, Michael S. BOWSHER, Jeffrey A. DESKUS, Kyle J. EASTMAN, Eric P. GILLIS, David B. FRENNESSON, Christiana IWUAGWU, John F. KADOW, B. Narasimhulu NAIDU, Kyle E. PARCELLA, Kevin M. PEESE, Mark G. SAULNIER, Prasanna SIVAPRAKASAM
  • PYRIDIN-3-YL ACETIC ACID DERIVATIVES AS INHIBITORS OF HUMAN IMMUNODEFICIENCY VIRUS REPLICATION
    Publication number: 20200016136
    Abstract: Disclosed are compounds of Formula I, including pharmaceutically acceptable salts, pharmaceutical compositions comprising the compounds, methods for making the compounds and their use in inhibiting HIV integrase and treating those infected with HIV or AIDS.
    Type: Application
    Filed: January 2, 2018
    Publication date: January 16, 2020
    Inventors: Michael S. BOWSHER, Jeffrey DESKUS, Kyle J. EASTMAN, Eric P. GILLIS, David B. FRENNESSON, Christiana IWUAGWU, B. Narasimhulu NAIDU, Kyle E. PARCELLA, Kevin M. PEESE, Mark G. SAULNIER, Prasanna SIVAPRAKASAM
  • 5H-pyrido[3,2-B]indole compounds as anticancer agents
    Patent number: 10174024
    Abstract: The present invention is directed to tricyclic compounds of formula (I), pharmaceutically acceptable compositions comprising compounds of the invention and said compositions for use in methods for the treatment of various disorders in particular cancer.
    Type: Grant
    Filed: May 11, 2016
    Date of Patent: January 8, 2019
    Assignee: Bristol-Myers Squibb Company
    Inventors: Wen-Ching Han, Andrew P. Degnan, Jeffrey A. Deskus, Ashvinikumar V. Gavai, Patrice Gill, William D. Schmitz, John E. Starrett, Jr.
  • Tricyclic compounds as anticancer agents
    Patent number: 9725449
    Abstract: The present invention is directed to tricyclic compounds of the formula wherein all substituents are defined herein, as well as pharmaceutically acceptable compositions comprising compounds of the invention and methods of using said compositions in the treatment of various disorders.
    Type: Grant
    Filed: May 10, 2016
    Date of Patent: August 8, 2017
    Assignee: Bristol-Myers Squibb Company
    Inventors: Derek J. Norris, Wayne Vaccaro, Mikkel V. DeBenedetto, Andrew P. Degnan, George V. Delucca, Jeffrey A. Deskus, Wen-Ching Han, Godwin Kwame Kumi, William D. Schmitz, John E. Starrett, Jr., Matthew D. Hill, Hong Huang
  • TRICYCLIC COMPOUNDS AS ANTICANCER AGENTS
    Publication number: 20160333013
    Abstract: The present invention is directed to tricyclic compounds of the formula wherein all substituents are defined herein, as well as pharmaceutically acceptable compositions comprising compounds of the invention and methods of using said compositions in the treatment of various disorders.
    Type: Application
    Filed: May 10, 2016
    Publication date: November 17, 2016
    Inventors: Derek J. Norris, Wayne Vaccaro, Mikkel V. DeBenedetto, Andrew P. Degnan, George V. Delucca, Jeffrey A. Deskus, Wen-Ching Han, Godwin Kwame Kumi, William D. Schmitz, John E. Starrett, JR., Matthew D. Hill, Hong Huang
  • Cyclopentyl indole derivatives
    Patent number: 7049314
    Abstract: The present invention relates to compounds of Formula (I) and pharmaceutically acceptable salts or solvates thereof and pharmaceutically acceptable formulations comprising said compounds useful for the treatment of premature ejaculation, depression, attention deficit hyperactivity disorder, obsessive-compulsive disorder, post-traumatic stress disorder and substance abuse disorders.
    Type: Grant
    Filed: September 15, 2003
    Date of Patent: May 23, 2006
    Assignee: Bristol-Myers Squibb Company
    Inventors: Dalton King, Jeffrey A. Deskus, John E. Macor, Ronald J. Mattson, Zhaoxing Meng, Charles P. Sloan
  • Cyclopropylindole derivatives as selective serotonin reuptake inhibitors
    Patent number: 6777437
    Abstract: The present invention relates to compounds of Formula (I) and pharmaceutically acceptable salts or solvates thereof and pharmaceutically acceptable formulations comprising said compounds useful for the treatment of depression, anxiety disorders, premature ejaculation, chronic pain, obsessive-compulsive disorder, feeding disorders, premenstrual dysphoric disorder, panic disorders and psychotic disorders including bipolar disorder and schizophrenia.
    Type: Grant
    Filed: March 5, 2002
    Date of Patent: August 17, 2004
    Assignee: Bristol-Myers Squibb Company
    Inventors: Ronald J. Mattson, Derek John Denhart, Jeffrey A. Deskus, Jonathan L. Ditta, Lawrence R. Marcin, James R. Epperson, John D. Catt, Dalton King, Mendi A. Higgins
  • Cyclopentyl indole derivatives
    Publication number: 20040077705
    Abstract: The present invention relates to compounds of Formula (I) and pharmaceutically acceptable salts or solvates thereof and pharmaceutically acceptable formulations comprising said compounds 1
    Type: Application
    Filed: September 15, 2003
    Publication date: April 22, 2004
    Inventors: Dalton King, Jeffrey A. Deskus, John E. Macor, Ronald J. Mattson, Zhaoxing Meng, Charles P. Sloan
  • Cyclopropylindole derivatives as selective serotonin reuptake inhibitors
    Publication number: 20030073849
    Abstract: The present invention relates to compounds of Formula (I) and pharmaceutically acceptable salts or solvates thereof and pharmaceutically acceptable formulations comprising said compounds 1
    Type: Application
    Filed: March 5, 2002
    Publication date: April 17, 2003
    Inventors: Ronald J. Mattson, Derek John Denhart, Jeffrey A. Deskus, Jonathan L. Ditta, Lawrence R. Marcin, James R. Epperson, John D. Catt, Dalton King, Mendi A. Higgins