Patents by Inventor Jeffrey A. Kern

Jeffrey A. Kern has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • Patent number: 11186652
    Abstract: A method of lipopolysaccharide (LPS) extraction from gram negative bacterial cells is provided, said method comprising a step of extracting LPS from the gram negative bacterial cell in a LPS extraction solution comprising a salt, water, an alcohol, and a further organic solvent. Compositions and uses of the extracted LPS are also provided.
    Type: Grant
    Filed: December 21, 2016
    Date of Patent: November 30, 2021
    Assignee: GLAXOSMITHKLINE BIOLOGICALS SA
    Inventors: Jeffrey A. Kern, Chad Farrenburg
  • Publication number: 20200102405
    Abstract: A method of lipopolysaccharide (LPS) extraction from gram negative bacterial cells is provided, said method comprising a step of extracting LPS from the gram negative bacterial cell in a LPS extraction solution comprising a salt, water, an alcohol, and a further organic solvent. Compositions and uses of the extracted LPS are also provided.
    Type: Application
    Filed: December 21, 2016
    Publication date: April 2, 2020
    Applicant: GLAXOSMITHKLINE BIOLOGICALS, S.A.
    Inventors: Jeffrey A. KERN, Chad FARRENBURG
  • Patent number: 9206995
    Abstract: A duct adapter system directs air flow relative to a hybrid water heater. The duct adapter system includes a collar adapted to surround a vent of a hybrid water shroud. The collar couples to standard duct pipe to extend ductwork to a heat pump portion of the hybrid water heater. A boost fan may be included in the system for boosting air flow to or from a remote location. The duct adapter system is adapted to deliver a warm air supply to the heat pump from the remote location, or deliver the cool discharge air from the heat pump water heater to a remote location.
    Type: Grant
    Filed: July 7, 2011
    Date of Patent: December 8, 2015
    Assignee: General Electric Company
    Inventors: Jonathan D. Nelson, Michael Thomas Beyerle, Jeffrey A. Kern, Eliel Fresco Rodriguez
  • Publication number: 20120023990
    Abstract: A duct adapter system directs air flow relative to a hybrid water heater. The duct adapter system includes a collar adapted to surround a vent of a hybrid water shroud. The collar couples to standard duct pipe to extend ductwork to a heat pump portion of the hybrid water heater. A boost fan may be included in the system for boosting air flow to or from a remote location. The duct adapter system is adapted to deliver a warm air supply to the heat pump from the remote location, or deliver the cool discharge air from the heat pump water heater to a remote location.
    Type: Application
    Filed: July 7, 2011
    Publication date: February 2, 2012
    Inventors: Jonathan D. Nelson, Michael Thomas Beyerle, Jeffrey A. Kern, Eliel Fresco Rodriguez
  • Patent number: 7153828
    Abstract: Ligands which bind to the HER2, HER3 and/or HER4 receptors are useful as normal epithelial cell growth factors.
    Type: Grant
    Filed: June 3, 2003
    Date of Patent: December 26, 2006
    Assignees: Genentech, Inc., University of Iowa Research Foundation
    Inventors: Mark X. Sliwkowski, Jeffrey A. Kern
  • Publication number: 20030199429
    Abstract: Ligands which bind to the HER2, HER3 and/or HER4 receptors are useful as normal epithelial cell growth factors.
    Type: Application
    Filed: June 3, 2003
    Publication date: October 23, 2003
    Applicant: Genentech, Inc.
    Inventors: Mark X. Sliwkowski, Jeffrey A. Kern
  • Publication number: 20030108565
    Abstract: Hydrophobic ion pairing (HIP) is applied to solubilize proteins and/or adjuvants in an organic medium. A polymer is cosolubilized in the medium and microspheres encapsulating the protein and/or adjuvant can be produced by a single emulsion method. Microspheres prepared by this method exhibit low initial burst of the protein and gradual release over time, and elicit a strong and comprehensive immune response. Compositions comprising a protein and an adjuvant co-encapsulated in microspheres are provided.
    Type: Application
    Filed: July 10, 2002
    Publication date: June 12, 2003
    Inventors: Mark E. Johnson, Jay T. Evans, Jeffrey A. Kern
  • Publication number: 20020042087
    Abstract: Ligands which bind to the HER2, HER3 and/or HER4 receptors are useful as normal epithelial cell growth factors.
    Type: Application
    Filed: February 23, 2001
    Publication date: April 11, 2002
    Inventors: Mark X. Sliwkowski, Jeffrey A. Kern
  • Publication number: 20010023241
    Abstract: Ligands which bind to the HER2, HER3 and/or HER4 receptors are useful as normal epithelial cell growth factors.
    Type: Application
    Filed: February 2, 2001
    Publication date: September 20, 2001
    Inventors: Mark X. Sliwkowski, Jeffrey A. Kern
  • Patent number: 4923366
    Abstract: A reversible turbine pump includes a pair of end walls and a side wall defining an annular pumping chamber. A turbine impeller mounted for reversible rotation in the chamber includes a rigid input shaft. One end of the shaft extends through one end wall and is sealed from the chamber. A spring biases the other end of the shaft toward the other end wall. Cooperating thrust bearing members, mounted to the other end of the shaft and the other end wall, provide a large planar area of low friction engagement therebetween. The pumping chamber has a pair of inlets, a pair of outlets and a dam. The first inlet and second outlet are on one side of the dam while the second inlet and first outlet are on the other side of the dam so that reverse rotation of the impeller pumps fluid in opposite directions through a different set of inlet and outlet. Valves associated with the inlets and outlets permit fluid flow in the desired direction and prevent fluid flow in the opposite direction.
    Type: Grant
    Filed: February 1, 1989
    Date of Patent: May 8, 1990
    Assignee: General Electric Company
    Inventors: Jeffrey A. Kern, Roger L. Hoffman
  • Patent number: 4812624
    Abstract: A temperature sensor assembly for an automatic solid disk surface unit includes a temperature sensor enclosed in a metallic hermetically sealed generally cylindrical housing. Upper and lower centrally apertured annular disks formed of a porcelain ceramic material thermally isolate the sensor housing from the surrounding surface unit. A protective metallic skirt conforming to the outer contour of the insulating disks holds the assembly together. A layer of glaze material covers the exposed upper surface of the upper disk in the gap between the skirt and the housing to prevent the absorption of food soils.
    Type: Grant
    Filed: December 28, 1987
    Date of Patent: March 14, 1989
    Assignee: General Electric Company
    Inventor: Jeffrey A. Kern