Abstract: A method of filtration in a process vessel using a treated filter media which has been treated with a conditioner for improved filtration of contaminants is provided. The treated filter media can be used in process vessels for refining, petrochemical, and chemical plants to treat process streams. The conditioner can be the same material as what is expected to be captured during the fouling process. In other words, the conditioner that is added to the treated filter media can be the same material as the contaminant in the fluid stream to be treated. This allows for chemical compatibility with an existing process fluid stream. This also allows for the natural continuation of the filtration process.

Abstract: Waterborne dispersions including crosslinkable multistage polymeric particles useful in coating compositions are provided. The multistage particles have a last-formed layer that includes a diketone functionality that is capable of crosslinking via a dihydrazide component also included in the dispersion. Another embodiment of the waterborne dispersion further includes crosslinkable latex particles having a diketone functionality that are capable of crosslinking with each other and/or the multistage particles via the dihydrazide component. An emulsion polymerization process for forming the multistage particles also is provided. Also provided are coating compositions that contain either embodiment of the waterborne dispersions.

Abstract: It relates to a pharmaceutical combination comprising a KRAS G12C inhibitor, in particular 1-{6-[(4M)-4-(5-Chloro-6-methyl-1H-indazol-4-yl)-5-methyl-3-(1-methyl-1H-indazol-5-yl)-1H-pyrazol-1-yl]-2-azaspiro [3.3] heptan-2-yl} prop-2-en-1-one (Compound A) and one or more therapeutically active agents selected from a SHP2 inhibitor (e.g. TNO155) and a PD-1 inhibitor, pharmaceutical compositions comprising the same; and methods of using such combinations and compositions in the treatment or prevention of a cancer or a tumor, in particular wherein the cancer or tumor is KRAS G12C mutated.

Abstract: A bipod support for a drain cleaning machine is described. The bipod support includes a base, a plurality of legs, a retaining member, and a latch. The retaining member and latch are configured to engage and secure the drain cleaning machine to the bipod support. The bipod support enables rocking movement of the drain cleaning machine while supporting the weight of the machine. Also described are related methods of use of the bipod support.

Abstract: A shelf stable fried product and a process for creating a shelf stable fried product is disclosed. Aspects include a process for managing fat migration, moisture migration, and cell degrading of a food product during frying. Aspects further include a resulting shelf stable food product that includes a crispy and/or crunchy texture and a desirable fat distribution.

Abstract: An anionically-stabilized aqueous emulsion composition includes a) a first emulsion polymer having a Tg from ?60° C. to 40° C.; b) a volatile base; and c) polymeric particles, different from the first emulsion polymer and present in emulsified form. The c) polymeric particles are polyamine graft copolymers, in which vinyl monomers form a polymer grafted to a water-soluble amino-group containing polymer. The anionically-stabilized aqueous emulsion composition may have a pH of from 8 to 11.

Abstract: A shelf stable fried product and a process for creating a shelf stable fried product is disclosed. Aspects include a process for managing fat migration, moisture migration, and cell degrading of a food product during frying. Aspects further include a resulting shelf stable food product that includes a crispy and/or crunchy texture and a desirable fat distribution.

Abstract: An anchor configured to maximize the surface area of the anchor to improve anchor retention is disclosed. The anchor may be configured with a width that differs from a thickness of the anchor. In some embodiments, the anchor be configured as a helical ribbon defining a central lumen about a central axis extending through the helical ribbon. The helical ribbon may vary in width, thickness, central lumen diameter, or a combination thereof, along its extent. The anchor may include retention features that are configured to promote tissue and/or implant interaction for improved anchor retention.

Abstract: A three wheeled stand-up or sit down foldable and portable electric personal mobility vehicle for fulfilling the needs of a broad spectrum of users including the handicapped and recreational users. The personal mobility vehicle has two major parts, including a front wheel frame assembly and a rear frame chassis assembly. These major parts are configured to easily fold into a smaller size so that the vehicle can be easily transportable and more conveniently stored. Furthermore, a versatile seat and seat post are implemented to enable a user to sit or stand, and the seat can be easily removed, without tools, to create more space should a user wish.

Abstract: A shelf stable fried product and a process for creating a shelf stable fried product is disclosed. Aspects include a process for managing fat migration, moisture migration, and cell degrading of a food product during frying. Aspects further include a resulting shelf stable food product that includes a crispy and/or crunchy texture and a desirable fat distribution.

Abstract: Provided are peptoid-peptide macrocycles. The peptoid-peptide macrocycles may have inhibitory activity towards the Wnt signaling pathway. The Wnt signaling pathway is associated with cancer and other diseases and conditions. Such diseases include, for example, pulmonary fibrosis. Also described are methods of making the peptoid-peptide macrocycles, compositions containing the peptoid-peptide macrocycles, and methods of using the peptoid-peptide macrocycles.

Abstract: A shelf stable fried product and a process for creating a shelf stable fried product is disclosed. Aspects include a process for managing fat migration, moisture migration, and cell degrading of a food product during frying. Aspects further include a resulting shelf stable food product that includes a crispy and/or crunchy texture and a desirable fat distribution.

Abstract: Compounds comprising one or more functionalized fatty acid esters, which may be derived from bio-based oils, are used as a low-VOC coalescent agent (i.e., a coalescent agent having a low content of volatile organic compounds) in waterborne coating compositions. The functional group can be epoxide, vicinal diol, hydroxy phosphotriester, hydroxy ester, hydroxyl alkyl ester, hydroxyl benzyl ester, hydroxy ether, hydroxy amino, hydroxy sulfide, hydroxy nitrile, hydroxy amine, terminal alcohol, thiiran, ketone, or cyclic carbonate. The present disclosure also relates to waterborne coating compositions comprising these functionalized fatty acid esters.

Abstract: A three wheeled stand-up or sit down portable two part personal mobility vehicle suited to fulfilling the needs of a broad spectrum of drivers including the handicapped having walking disabilities and recreational users. The vehicle is configured to easily fold and collapse without the use of tools to thereby provide a convenient way for all people, including the handicapped or those lacking normal strength, to handle and store their vehicle. The folding mechanism is implemented with the steering column of the vehicle and enables the handlebar assembly to easily fold downward.

Abstract: According to examples, a self-driving vehicle (“SDV”) is operable to select one of (i) an autonomous localization mode, in which the SDV autonomously operates using a localization map, or (ii) an autonomous neural network mode, in which the SDV uses a neural network component that implements one or more machine learning models. The SDV can autonomously operate on at least a segment of a planned route using the selected one of the autonomous localization mode or the autonomous neural network mode.

Abstract: A shelf stable fried product and a process for creating a shelf stable fried product is disclosed. Aspects include a process for managing fat migration, moisture migration, and cell degrading of a food product during frying. Aspects further include a resulting shelf stable food product that includes a crispy and/or crunchy texture and a desirable fat distribution.

Abstract: In one aspect, the present disclosure pertains to lubricous coating compositions that comprise (a) a higher molecular weight polyvinylpyrrolidone, (b) a lower molecular weight polyvinylpyrrolidone, (c) a copolymer of sodium acrylate and acrylamide or a copolymer of acrylic acid and acrylamide, and (d) a polyfunctional unsaturated crosslinking agent. In some embodiments, such lubricous coating compositions are present in crosslinked form on the surface of a medical article. In some embodiments, the lubricous coating compositions further comprise a solvent, in which case such compositions may be, for example, applied to a substrate in the form of a layer and subsequently crosslinked, thereby forming a lubricious coating on the substrate.

Abstract: A shelf stable fried product and a process for creating a shelf stable fried product is disclosed. Aspects include a process for managing fat migration, moisture migration, and cell degrading of a food product during frying. Aspects further include a resulting shelf stable food product that includes a crispy and/or crunchy texture and a desirable fat distribution.

Abstract: A three wheeled stand-up or sit down foldable and portable electric personal mobility vehicle suited to fulfilling the needs of a broad spectrum of users. The front end wheel assembly comprises an electrically powered front wheel hub motor that provides power to move forward and backward. An electric control box mounted flush to the steering fork assembly with means of electrically connecting hub motor, battery, and controls. An upper sub-part comprises a telescopic handlebar to control direction of the front wheel, controls comprising a brake lever, throttle, and forward/reverse switch to control speed, and an ignition headlight assembly with removable keys. Below the handle bars comprise a folding column enabling the steering column and handlebar assembly to fold down.

Abstract: A three wheeled stand-up or sit down portable two part personal mobility vehicle suited to fulfilling the needs of a broad spectrum of drivers. The front end of the chassis is disposed with a front wheel electrically powered hub motor that provides power to move forward and backward. An electric control box mounted flush to the steering fork assembly with means of electrically connecting hub motor, battery, and controls. An upper sub-part comprises a telescopic handlebar to control direction of the front wheel, controls comprising a brake lever, throttle, and forward/reverse switch to control speed, and an ignition headlight assembly with removable keys. Below the handle bars comprises a folding column enabling the steering column and handlebar assembly to fold down.