Abstract: The specification relates to compounds of Formula (1): and to pharmaceutically acceptable salts thereof, to processes and intermediates used for their preparation, to pharmaceutical compositions containing them and to their use in the treatment of cancer.

Abstract: A patient containment system for securing a patient to a patient transport apparatus, comprising a first lower strap and a second lower strap. Each of the first lower strap and the second lower strap have a thigh region, a waist region, and a connection region arranged between the thigh region and the waist region. A first connector is coupled to the connection region of the first lower strap. A second connector is coupled to the connection region of the second lower strap, and is configured to releasably attach to the first connector to at least partially limit movement of the first lower strap relative to the second lower strap. The connection region defines a connection width, and the thigh region defines a thigh width larger than the connection width.

Abstract: A physiologically stable fluorophore includes a terminal moiety including a terminal reactive site that reacts with a reactive group of a substrate; a stability linker covalently bonded to the terminal moiety; and a bridge moiety covalently bonded to the stability linker such that the stability linker is interposed through chemical bonds between the bridge moiety and the terminal moiety; and a fluorescent moiety covalently bonded to the bridge moiety of the redox moiety and including: an electron bandgap mediator that is covalently bonded to the bridge moiety; a coordinate center covalently bonded to the electron bandgap mediator and that forms a Zwitterionic member with an atom in the electron bandgap mediator; and a steric hinder bonded to the electron bandgap mediator to provide steric hindrance for protection of the coordinate center.

Abstract: The present invention relates to an ingredient blending system and method for use in frozen beverage equipment and soft-serve ice cream equipment. In an exemplary embodiment, a manifold body has at least one blending chamber, more than one ingredient inlet port, more than one pressure reservoir, more than one ingredient egress port that intersects the pressure reservoir, and more than one ingredient ingress port that intersects the blending chamber. More than one inlet conduit is fastened to each of the ingredient inlet ports, more than one pressure sensor is secured within each of the pressure reservoirs, and more than one electronic valve is secured to the manifold body. In accordance with a recipe pulse sequence, the ingredients are blended in the blending chamber forming a food product, and injected into the mixing cylinder where the food product is chilled and dispensed to a customer for consumption.

Abstract: The present invention relates to azaquinolone compounds of Formula (I), and their use in medicine.

Abstract: The present invention relates to azaquinolone compounds of Formula (I), and their use in medicine.

Abstract: A platform with an auto-router takes into account non-navigation data, such as IR image sensor data or other non-navigation data to develop a route for a platform. The non-navigation data may be obtained from existing non-navigation sensors carried by the platform. The non-navigation data is fed to an auto-router that takes into account the non-navigation data to generate or dynamically alter a route for the platform.

Abstract: A vehicle sharing system includes a vehicle having interior transceiver modules associated with different passenger seating areas and a vehicle computing system (VCS) including a processor and a memory in communication with the modules and programmed to detect occupancy status of each seating area based on signals from the modules and to communicate the occupancy statuses to a remote server to facilitate scheduling of ride-sharing passengers for a specified seating area of the vehicle. The reserved seating location may be used to align the seating location/door with a passenger during pick-up, adjust vehicle accessory settings associated with the reserved seating location, and activate a visual indicator to direct the passenger to the assigned/reserved seating location.

Abstract: A vehicle sharing system includes a vehicle having interior transceiver modules associated with different passenger seating areas and a vehicle computing system (VCS) including a processor and a memory in communication with the modules and programmed to detect occupancy status of each seating area based on signals from the modules and to communicate the occupancy statuses to a remote server to facilitate scheduling of ride-sharing passengers for a specified seating area of the vehicle. The reserved seating location may be used to align the seating location/door with a passenger during pick-up, adjust vehicle accessory settings associated with the reserved seating location, and activate a visual indicator to direct the passenger to the assigned/reserved seating location.

Abstract: A vehicle sharing system includes a vehicle having interior transceiver modules associated with different passenger seating areas and a vehicle computing system (VCS) including a processor and a memory in communication with the modules and programmed to detect occupancy status of each seating area based on signals from the modules and to communicate the occupancy statuses to a remote server to facilitate scheduling of ride-sharing passengers for a specified seating area of the vehicle. The reserved seating location may be used to align the seating location/door with a passenger during pick-up, adjust vehicle accessory settings associated with the reserved seating location, and activate a visual indicator to direct the passenger to the assigned/reserved seating location.

Abstract: The present invention relates to azaquinolone compounds of Formula (I), and their use in medicine.

Abstract: A platform with an auto-router takes into account non-navigation data, such as IR image sensor data or other non-navigation data to develop a route for a platform. The non-navigation data may be obtained from existing non-navigation sensors carried by the platform. The non-navigation data is fed to an auto-router that takes into account the non-navigation data to generate or dynamically alter a route for the platform.

Abstract: The present invention relates to azaquinolone compounds of Formula (I), and their use in medicine.

Abstract: The present invention relates to azaquinolone compounds of Formula (I), and their use in medicine.

Abstract: A vehicle sharing system includes a vehicle having interior transceiver modules associated with different passenger seating areas and a vehicle computing system (VCS) including a processor and a memory in communication with the modules and programmed to detect occupancy status of each seating area based on signals from the modules and to communicate the occupancy statuses to a remote server to facilitate scheduling of ride-sharing passengers for a specified seating area of the vehicle. The reserved seating location may be used to align the seating location/door with a passenger during pick-up, adjust vehicle accessory settings associated with the reserved seating location, and activate a visual indicator to direct the passenger to the assigned/reserved seating location.

Abstract: A payment card security system includes a payment card provider account system communicatively coupled to a payment card transaction device and a mobile device. The payment card transaction device sends an indication that a payment card is being used to perform a transaction. The payment card provider account system includes processors that receive the indication that the payment card is being used to perform the transaction from the payment card transaction device. The processors also send a notification indicating that the payment card is being used to perform the transaction. The processors further enable authorization of the transaction via the mobile device. In this manner, the payment card security system may prevent or reduce the occurrence of suspicious transactions as they are occurring, rather than waiting until after they have occurred.

Abstract: One or more sensors of a virtual reality device track a pose of the virtual reality device. The virtual reality device requests a virtual image having a perspective corresponding to a future pose from a remote computer. After receiving the requested virtual image, the virtual reality device adjusts the virtual image to an adjusted virtual image having an updated perspective corresponding to an updated tracked pose of the virtual reality device. Then, a virtual reality display displays the adjusted virtual image.

Abstract: The present invention relates to azaquinolone compounds of Formula (I), and their use in medicine.

Abstract: A threat warning system and method for navigation and geolocation in Global Positioning System (GPS)-denied environments using the threat warning system is disclosed. A threat warning system carried on a platform is provided. The threat warning system includes at least one detector, at least one threat warning image sensor, at least one processor, Global Positioning System (GPS) detection logic, last known position data logic, registration logic, navigation solution logic, position correction logic, and guiding logic.

Abstract: A method for making an expanded, and optionally multi-component and/or colored PTFE monofilament is disclosed. The method includes forming a first paste by mixing a PTFE powder with a hydrocarbon solvent; forming an extrusion preform by pressing the first paste into a form; curing the extrusion preform by exposing the extrusion preform to a first temperature for a first time duration; forming a green monofilament by extruding the first paste through a die; expanding the green monofilament by exposing the green monofilament to a second temperature for a second time duration, the second time duration occurring after the first time duration; stretching the green monofilament substantially along a longitudinal axis of the green monofilament, the stretching the green monofilament occurring after the expanding the green monofilament; and sintering the green monofilament after the stretching the green monofilament.