Abstract: Provided herein, inter alia, are methods and compositions for treating diabetes mellitus comprising co-transplantation of an insulin-producing cell and a cell derived from a parathyroid gland (PTG), a CD34+ cell derived from a parathyroid gland, a CD34+ cell derived from a stem cell, or other progenitor cell-derived CD34+ cell.

Abstract: Waste disposer systems and cover switch mechanisms for implementation in such systems, and related methods, are disclosed. In an example embodiment, a cover switch mechanism includes a cord, a body configured to be coupled to a top portion of a disposer, and connecting components. The connecting components include a terminal cover configured to be coupled to a bottom portion of the disposer, a switch interface connector, and a connection component. The cord extends between the body and cover, where an end of the cord extending into the cover includes first and second leads. The first lead is coupled to the interface connector, and the cover is configured to receive a second end of a power link. The interface connector is configured to be coupled to a third lead of the link, and the connection component is configured to couple the second lead with a fourth lead of the link.

Abstract: In one embodiment, the present invention is directed to a contact hearing system comprising: an ear tip including a transmit coil, wherein the transmit coil is connected to an audio processor, including an H Bridge circuit; a first input to the H Bridge circuit comprising an AND circuit wherein a first input to the AND circuit comprises a carrier signal and a second input to the AND circuit comprises an output of a delta sigma modulation circuit, wherein the delta sigma modulation circuit is a component of the audio processor; and a second input to the H Bridge circuit comprising an NAND circuit wherein a first input to the NAND circuit comprises a carrier signal and a second input to the NAND circuit comprises an output of the delta sigma modulation circuit.

Abstract: A human motion assistance device has an upper torso harness and a preloaded leg strap arrangement affixed to the upper torso harness. The preloaded leg strap arrangement has an X-bracket connected to the upper torso harness. The preloaded leg strap arrangement further uses a plurality of blocks and a preloaded strap routed through the blocks and connected to the X-bracket. The preloaded leg strap arrangement further uses a knee pad with a split seam. The preloaded strap is under tension, even when the human motion assistance device is in a relaxed state. The preloading provides an immediate force which increases under a loaded state. The potential energy stored during the loaded state is released when transitioning from a standing position to a crouched, squatting, or seated position. The configuration allows for maximizing the energy storage without putting excess shoulder pressure on the user when standing.

Abstract: A human motion assistance device has upper back straps and is configured to attach to a user. A leg strap arrangement with lower back straps is configured to attach to the user. A differential assembly is connected between the upper back straps and lower back straps to reduce resistance of the upper torso harness and leg strap arrangement during gait. When crouching or lifting, the differential assembly transfers force to stretch and retract the upper torso harness and leg strap arrangement, which provides human motion assistance. The differential assembly can be implements as an x-bar, lever arm, pulley, gears, or tube. The leg strap arrangement has a knee pad adapted to cover a knee of the user. The knee pad opens along a segment. The upper torso harness has a shoulder strap and buckle. The leg strap arrangement is an elastic material.

Abstract: In one embodiment, the present invention is directed to a contact hearing system comprising: an ear tip including a transmit coil, wherein the transmit coil is connected to an audio processor, including an H Bridge circuit; a first input to the H Bridge circuit comprising an AND circuit wherein a first input to the AND circuit comprises a carrier signal and a second input to the AND circuit comprises an output of a delta sigma modulation circuit, wherein the delta sigma modulation circuit is a component of the audio processor; and a second input to the H Bridge circuit comprising an NAND circuit wherein a first input to the NAND circuit comprises a carrier signal and a second input to the NAND circuit comprises an output of the delta sigma modulation circuit.

Abstract: A human motion assistance device has upper back straps and is configured to attach to a user. A leg strap arrangement with lower back straps is configured to attach to the user. A differential assembly is connected between the upper back straps and lower back straps to reduce resistance of the upper torso harness and leg strap arrangement during gait. When crouching or lifting, the differential assembly transfers force to stretch and retract the upper torso harness and leg strap arrangement, which provides human motion assistance. The differential assembly can be implements as an x-bar, lever arm, pulley, gears, or tube. The leg strap arrangement has a knee pad adapted to cover a knee of the user. The knee pad opens along a segment. The upper torso harness has a shoulder strap and buckle. The leg strap arrangement is an elastic material.

Abstract: In one embodiment, the present invention is directed to a contact hearing system comprising: an ear tip including a transmit coil, wherein the transmit coil is connected to an audio processor, including an H Bridge circuit; a first input to the H Bridge circuit comprising an AND circuit wherein a first input to the AND circuit comprises a carrier signal and a second input to the AND circuit comprises an output of a delta sigma modulation circuit, wherein the delta sigma modulation circuit is a component of the audio processor; and a second input to the H Bridge circuit comprising an NAND circuit wherein a first input to the NAND circuit comprises a carrier signal and a second input to the NAND circuit comprises an output of the delta sigma modulation circuit.

Abstract: A human motion assistance device has an upper torso harness for attaching to a user. The upper torso harness has a backpack assembly and shoulder strap, which buckles in front of the user. The upper torso harness can be IOTV. Leg straps are affixed to the upper torso harness proximate to a gluteal area of the user and configured to extend down a hamstring area to a knee pad and further extend down a tibia area. The knee pad opens along a vertical or angled segment and the calf portion opens over the calf. Seat webbing is connected to leg straps for additional support. Upper torso harness and leg straps are made with a combination of durable materials such as textured nylon, polyurethane coated polyester, as well as elastic material and webbing material. The upper torso harness and leg straps are passive without active members.

Abstract: A system for intraoral fluid delivery comprises a rate-controlled and/or volume-controlled fluid supply device, a reservoir for holding one or more fluids to be delivered to a patient's oral cavity, a mouthpiece to be worn by a patient at least partially within the patient's oral cavity, and tubing to carry the one or more fluids from the fluid supply device to the mouthpiece. The mouthpiece comprises a fluid inlet adjacent and/or exterior to the patient's oral cavity when the mouthpiece is worn by the patient, a fluid outlet posterior to the fluid inlet, and a fluid channel therebetween.

Abstract: In one embodiment, the present invention is directed to a contact hearing system comprising: an ear tip including a transmit coil, wherein the transmit coil is connected to an audio processor, including an H Bridge circuit; a first input to the H Bridge circuit comprising an AND circuit wherein a first input to the AND circuit comprises a carrier signal and a second input to the AND circuit comprises an output of a delta sigma modulation circuit, wherein the delta sigma modulation circuit is a component of the audio processor; and a second input to the H Bridge circuit comprising an NAND circuit wherein a first input to the NAND circuit comprises a carrier signal and a second input to the NAND circuit comprises an output of the delta sigma modulation circuit.

Abstract: A human motion assistance device has an upper torso harness and a preloaded leg strap arrangement affixed to the upper torso harness. The preloaded leg strap arrangement has an X-bracket connected to the upper torso harness. The preloaded leg strap arrangement further uses a plurality of blocks and a preloaded strap routed through the blocks and connected to the X-bracket. The preloaded leg strap arrangement further uses a knee pad with a split seam. The preloaded strap is under tension, even when the human motion assistance device is in a relaxed state. The preloading provides an immediate force which increases under a loaded state. The potential energy stored during the loaded state is released when transitioning from a standing position to a crouched, squatting, or seated position. The configuration allows for maximizing the energy storage without putting excess shoulder pressure on the user when standing.

Abstract: A human motion assistance device has an upper torso harness for attaching to a user. The upper torso harness has a shoulder strap or backpack assembly. A belt is connected to the upper torso harness and extends around a waist and back area of the user. Leg straps are affixed to the upper torso harness proximate to a gluteal area of the user and configured to extend down a hamstring area to cross in front of a knee area and further extend down a calf area to a foot anchor. The leg straps are made of an elastic material with a pocket around the knee area of the user. The foot anchor may extend under the heel to an arch strap, or cross over the talus and under the arch of the foot. The upper torso harness and leg straps are passive without active members.

Abstract: A human motion assistance device has upper back straps and is configured to attach to a user. A leg strap arrangement with lower back straps is configured to attach to the user. A differential assembly is connected between the upper back straps and lower back straps to reduce resistance of the upper torso harness and leg strap arrangement during gait. When crouching or lifting, the differential assembly transfers force to stretch and retract the upper torso harness and leg strap arrangement, which provides human motion assistance. The differential assembly can be implements as an x-bar, lever arm, pulley, gears, or tube. The leg strap arrangement has a knee pad adapted to cover a knee of the user. The knee pad opens along a segment. The upper torso harness has a shoulder strap and buckle. The leg strap arrangement is an elastic material.

Abstract: A system for intraoral fluid delivery comprises a rate-controlled and/or volume-controlled fluid supply device, a reservoir for holding one or more fluids to be delivered to a patient's oral cavity, a mouthpiece to be worn by a patient at least partially within the patient's oral cavity, and tubing to carry the one or more fluids from the fluid supply device to the mouthpiece. The mouthpiece comprises a fluid inlet adjacent and/or exterior to the patient's oral cavity when the mouthpiece is worn by the patient, a fluid outlet posterior to the fluid inlet, and a fluid channel therebetween.

Abstract: A system for intraoral fluid delivery comprises a rate-controlled and/or volume-controlled fluid supply device, a reservoir for holding one or more fluids to be delivered to a patient's oral cavity, a mouthpiece to be worn by a patient at least partially within the patient's oral cavity, and tubing to carry the one or more fluids from the fluid supply device to the mouthpiece. The mouthpiece comprises a fluid inlet adjacent and/or exterior to the patient's oral cavity when the mouthpiece is worn by the patient, a fluid outlet posterior to the fluid inlet, and a fluid channel therebetween.

Abstract: A human motion assistance device has an upper torso harness for attaching to a user. The upper torso harness has a backpack assembly and shoulder strap, which buckles in front of the user. The upper torso harness can be IOTV. Leg straps are affixed to the upper torso harness proximate to a gluteal area of the user and configured to extend down a hamstring area to a knee pad and further extend down a tibia area. The knee pad opens along a vertical or angled segment and the calf portion opens over the calf. Seat webbing is connected to leg straps for additional support. Upper torso harness and leg straps are made with a combination of durable materials such as textured nylon, polyurethane coated polyester, as well as elastic material and webbing material. The upper torso harness and leg straps are passive without active members.

Abstract: A human motion assistance device has an upper torso harness for attaching to a user. The upper torso harness has a shoulder strap or backpack assembly. A belt is connected to the upper torso harness and extends around a waist and back area of the user. Leg straps are affixed to the upper torso harness proximate to a gluteal area of the user and configured to extend down a hamstring area to cross in front of a knee area and further extend down a calf area to a foot anchor. The leg straps are made of an elastic material with a pocket around the knee area of the user. The foot anchor may extend under the heel to an arch strap, or cross over the talus and under the arch of the foot. The upper torso harness and leg straps are passive without active members.

Abstract: A prosthetic joint device includes a foot portion and a main body pivotally coupled to the foot portion at a first joint. A first compliant member is coupled to the main body and foot portion. A first clutch is coupled to the first compliant member. An actuator is coupled to the first clutch to lock and unlock the first clutch and engage and disengage the first compliant member. A control system is coupled to the actuator to control the actuator based on a gait activity. The first clutch is locked to engage the first compliant member. A second compliant member is coupled to the main body and foot portion. A sensor is coupled to the prosthetic joint device to measure a physical state of the prosthetic joint device. The engagement and disengagement of the first compliant member is timed based on the physical state of the prosthetic joint device.

Abstract: A prosthetic joint device includes a foot portion and a main body pivotally coupled to the foot portion at a first joint. A first compliant member is coupled to the main body and foot portion. A first clutch is coupled to the first compliant member. An actuator is coupled to the first clutch to lock and unlock the first clutch and engage and disengage the first compliant member. A control system is coupled to the actuator to control the actuator based on a gait activity. The first clutch is locked to engage the first compliant member. A second compliant member is coupled to the main body and foot portion. A sensor is coupled to the prosthetic joint device to measure a physical state of the prosthetic joint device. The engagement and disengagement of the first compliant member is timed based on the physical state of the prosthetic joint device.