Patents by Inventor Jeffrey Allen Dietrich

Jeffrey Allen Dietrich has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • Methods of generating protein variants
    Patent number: 8158383
    Abstract: The present invention provides methods of designing and generating polypeptide variants that have altered properties compared to a parent polypeptide. The present invention further provides a computer program product for carrying out the design of a variant polypeptide. The present invention further provides nucleic acids encoding enzyme variants, as well as vectors and host cells comprising the nucleic acids. The present invention further provides variant enzymes; methods of producing the variant enzymes; and methods of producing compounds using the enzymes.
    Type: Grant
    Filed: March 14, 2008
    Date of Patent: April 17, 2012
    Assignee: The Regents of the University of California
    Inventors: Jay D. Keasling, Yasuo Yoshikuni, Jeffrey Allen Dietrich, Farnaz F. Nowroozi, Patricia C. Babbitt
  • Artemisinic epoxide and methods for producing same
    Patent number: 8101399
    Abstract: The present invention provides artemisinic epoxide, and methods of synthesizing artemisinic epoxide in a genetically modified host cell. The present invention further provides methods for producing artemisinin. The present invention further provides variant enzymes that catalyze the oxidation of amorpha-4,11-diene to artemisinic epoxide; nucleic acids encoding the variant enzymes; as well as recombinant vectors and host cells comprising the nucleic acids.
    Type: Grant
    Filed: December 12, 2007
    Date of Patent: January 24, 2012
    Assignee: The Regents of the University of California
    Inventors: Jeffrey Allen Dietrich, Yasuo Yoshikuni, Jay D. Keasling, Michelle Chia-Yu Chang
  • METHODS OF GENERATING PROTEIN VARIANTS
    Publication number: 20080318292
    Abstract: The present invention provides methods of designing and generating polypeptide variants that have altered properties compared to a parent polypeptide. The present invention further provides a computer program product for carrying out the design of a variant polypeptide. The present invention further provides nucleic acids encoding enzyme variants, as well as vectors and host cells comprising the nucleic acids. The present invention further provides variant enzymes; methods of producing the variant enzymes; and methods of producing compounds using the enzymes.
    Type: Application
    Filed: March 14, 2008
    Publication date: December 25, 2008
    Applicant: THE REGENTS OF THE UNIVERSITY OF CALIFORNIA
    Inventors: JAY D. KEASLING, YASUO YOSHIKUNI, JEFFREY ALLEN DIETRICH, FARNAZ F. NOWROOZI, PATRICIA C. BABBITT
  • ARTEMISINIC EPOXIDE AND METHODS FOR PRODUCING SAME
    Publication number: 20080187983
    Abstract: The present invention provides artemisinic epoxide, and methods of synthesizing artemisinic epoxide in a genetically modified host cell. The present invention further provides methods for producing artemisinin. The present invention further provides variant enzymes that catalyze the oxidation of amorpha-4,11-diene to artemisinic epoxide; nucleic acids encoding the variant enzymes; as well as recombinant vectors and host cells comprising the nucleic acids.
    Type: Application
    Filed: December 12, 2007
    Publication date: August 7, 2008
    Inventors: Jeffrey Allen DIETRICH, Yasuo Yoshikuni, Jay D. Keasling, Michelle Chia-Yu Chang