Abstract: A product supply chain may be viewed not just as a series of discrete, unrelated shipment transactions, but as a “process” (or pipeline) that can be subject to statistical process control. The present invention is directed to novel systems and methods for collecting data concerning one or more aspects of a supply chain, for performing statistical analysis on the collected data to facilitate the identification of anomalies or inefficiencies in the process, and for communicating the results of such statistical analysis to those responsible for the supply chain so that remedial measures may be taken, if appropriate. Among other things, a method is disclosed for use in a system in which at least one first sensor is associated with at least one first item that is transported from a first shipping location to a first receiving location so that the at least one first sensor can monitor at least one physical or environmental condition of the at least one first item as the at least one first item is so transported.