Abstract: An ampoule opener for opening a glass ampoule containing a medication. The ampoule opener has a transparent, cylindrical container removably attached to an annular metal base. A rubber flap member is attached to the inner edge of the base. The flap member is divided into flaps by one or more slits. A pair of scoring assemblies are attached to the bottom portion of the base. Each scoring assembly has a blade attached to a spring and a finger grip. The top of the ampoule to be opened is inserted through the flap member so that the blades align with the ampoule neck. The finger grips are compressed to engage the blades with the ampoule, and the ampoule is rotated to score the neck. The finger grips are then released, and the flaps hold the ampoule while the neck is snapped. The ampoule top is secured by the rubber flaps until the top is pushed into the container by the insertion of the next ampoule. The container holds a plurality of ampoule tops.