Abstract: The subject disclosure is directed towards a virtual touchpad comprising a region in space positioned relative to a detected user with which a user interacts by hand movements as determined from frames of depth data obtained via a depth camera. The user's hand position or positions in the virtual touchpad region may be converted to coordinates, such as for posting to a message queue for use by an application. The computing device and depth camera may be incorporated into a robot that moves on a floor, with the depth camera angled upwardly and the virtual touchpad region tilted to facilitate user interaction.