Patents by Inventor Jeffrey C. McGuire

Jeffrey C. McGuire has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • Vector for high level gene expression
    Patent number: 4798791
    Abstract: Methods and vectors for high level expression of genes in bacteria are disclosed. A terminal mRNA sequence from a gene coding for a stable bacterial protein mRNA is ligated to a gene coding for the desired protein adjacent the translation termination codon of the gene. The gene for the desired protein and the terminal mRNA sequence are situated in an expression vector in which the gene is operably linked to a transcription promoter.
    Type: Grant
    Filed: November 16, 1984
    Date of Patent: January 17, 1989
    Assignee: Genex Corporation
    Inventors: David M. Anderson, Jeffrey C. McGuire
  • Phenylalanine ammonia lyase-producing microbial cells
    Patent number: 4681850
    Abstract: This invention relates to novel microbial strains which produce phenylalanine ammonia-lyase in the absence of an inducer. Also disclosed is a method for making phenylalanine.
    Type: Grant
    Filed: November 20, 1984
    Date of Patent: July 21, 1987
    Assignee: Genex Corporation
    Inventor: Jeffrey C. McGuire
  • Phenylalanine ammonia lyase-producing microbial cells
    Patent number: 4636466
    Abstract: This invention relates to novel microbial strains which produce phenylalanine ammonia-lyase. These novel microbial strains have the ability to grow on minimal essential media which contain, as substantially the sole carbon source, L-tyrosine. Also disclosed are methods for making phenylalanine ammonia-lyase and methods for making phenylalanine.
    Type: Grant
    Filed: October 31, 1983
    Date of Patent: January 13, 1987
    Assignee: Genex Corporation
    Inventors: Jeffrey C. McGuire, John P. Montgomery, Huei-Hsuing Yang
  • Phenylalanine ammonia lyase-producing microbial cells
    Patent number: 4598047
    Abstract: A method for producing and isolating catabolite resistant, phenylalanine ammonia-lyase-producing microorganisms is disclosed. Also disclosed are novel catabolite resistant organisms and a method for producing L-phenylalanine using such organisms.
    Type: Grant
    Filed: June 25, 1984
    Date of Patent: July 1, 1986
    Assignee: Genex Corporation
    Inventor: Jeffrey C. McGuire
  • Maggiemycin, anhydromaggiemycin and processes for making
    Patent number: 4501699
    Abstract: New anthracyclinones, including maggiemycin, anhydromaggiemycin and 7-oxidodaunorubicinone, have been prepared. Maggiemycin, anhydromaggiemycin, and 7-oxidodaunorubicinone all exhibit biological activity; they are toxic to cell lines KB, L1210 and P388.
    Type: Grant
    Filed: November 1, 1982
    Date of Patent: February 26, 1985
    Assignee: Litton Bionetics, Inc.
    Inventors: Ramesh C. Pandey, Margaret W. Toussaint, Jeffrey C. McGuire, Monica C. Thomas