Patents by Inventor Jeffrey C. Wigle

Jeffrey C. Wigle has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • Slow release calcium composition
    Patent number: 11103528
    Abstract: A slow-release free calcium composition is disclosed which includes at least one polar solvent, from about 1 ?M to about 0.25 M substituted or unsubstituted cyclodextrin molecules, and from about 1 ppm to about 1000 ppm calcium cations. The cyclodextrin molecules each have a toroidal shape with an inner cavity and the calcium cations are encapsulated within the inner cavities of the cyclodextrins molecules. A method for making the composition and a method for administering a slow-release form of calcium to a patient is also disclosed.
    Type: Grant
    Filed: August 25, 2020
    Date of Patent: August 31, 2021
    Assignee: United States of America as represented by the Secretary of the Air Force
    Inventors: Sajid Liu, Jingbo Liu, Jeffrey C. Wigle
  • Ytterbium as a surrogate cation to measure calcium flux
    Patent number: 10670609
    Abstract: A method for tracking calcium flux of a eukaryotic cell. The method includes growing the eukaryotic cell in the presences of a ytterbium salt in solution and spectroscopically measuring ytterbium in the eukaryotic cell.
    Type: Grant
    Filed: September 22, 2017
    Date of Patent: June 2, 2020
    Inventors: Jingbo Liu, Sajid Bashir, Jeffrey C. Wigle
  • YTTERBIUM AS A SURROGATE CATION TO MEASURE CALCIUM FLUX
    Publication number: 20190094241
    Abstract: A method for tracking calcium flux of a eukaryotic cell. The method includes growing the eukaryotic cell in the presences of a ytterbium salt in solution and spectroscopically measuring ytterbium in the eukaryotic cell.
    Type: Application
    Filed: September 22, 2017
    Publication date: March 28, 2019
    Applicant: Government of the United States, as represented by the Secretary of the Air Force
    Inventors: Jingbo Liu, Sajid Bashir, Jeffrey C. Wigle