Abstract: An adjustable lounge seat includes a seat frame having a front end and a rear end, a back frame pivotably coupled to the rear end of the seat frame, a first assembly coupled to the seat frame proximate the rear end thereof and configured to couple to a track assembly where the first assembly is configured to facilitate moving the rear end of the seat frame up and down, a second assembly coupled to the seat frame proximate the front end thereof and configured to couple to the track assembly where the second assembly is configured to facilitate moving the front end of the seat frame up and down, and a footrest coupled to the front end of the seat frame and the second assembly where the footrest is movable between a stowed orientation and an extended orientation.

Abstract: A lounge seat for a vehicle defines a seat reference point. The lounge seat includes a seat frame assembly, a back frame assembly pivotably coupled to the seat frame assembly, a track assembly coupled to the seat frame assembly and configured to facilitate translating the seat frame assembly in a X direction, and a plurality of motors configured to cause movement of the seat frame assembly, the back frame assembly, and the track assembly to adjust the lounge seat between a full upright orientation associated with an initial X position of the seat reference point along the X direction and a full down orientation associated with a final X position of the seating reference point along the X direction.

Abstract: Disclosed herein are antisense compounds and methods for selectively reducing expression of an allelic variant of a huntingtin gene containing a single nucleotide polymorphism (SNP). Such methods, compounds, and composition are useful to treat, prevent, or ameliorate Huntington's Disease (HD).

Abstract: Various aspects describe an information platform for consistently integrating and/or quantifying the underlying principles of ESG into financial analyses, analytical tools, metrics, and/or available information on reviewed companies, business entities, etc., and further provide integration of analysis with community-based insight, contextual information and tools for readily understanding both. Various embodiments implement machine learning tools for curating data sources and incorporating the data sources into the knowledge platform. The incorporation of AI moderated information sources enables succinct views of often massive information pools, and further provides for transitions between types of information (e.g., qualitative, quantitative, and interactive data source (e.g., engagements, collaborative information, etc.)).

Abstract: Various aspects describe an information platform for consistently integrating and/or quantifying the underlying principles of ESG into financial analyses, analytical tools, metrics, and/or available information on reviewed companies, business entities, etc. . . . , and further provide integration of analysis with community-based insight, contextual information and tools for readily understanding both. Various embodiments implement machine learning tools for curating data sources and incorporating the data sources into the knowledge platform. The incorporation of AI moderated information sources enables succinct views of often massive information pools, and further provides for transitions between types of information (e.g., qualitative, quantitative, and interactive data source (e.g., engagements, collaborative information, etc.)).

Abstract: A watercraft mooring device is provided. The mooring device provides a rigid body extending between a rigid hook portion and an elastic loop connectable to the watercraft. The rigid hook portion has a distal end that transitions by way of a curvature to a proximal end rigidly connected to the rigid body. A foam layer may encase the rigid body, giving floatation properties to the mooring device as well as bumper capabilities. The prong of the hook portion is dimensioned and adapted to slide through a slot of a cleat or the like on a docking structure, whereby the curvature enables a pivotal connection so that the loop end of mooring device may move vertically out of plane with the cleat slot, while the rigidity of the hook portion and the rigid body of the mooring device keeps the watercraft spaced apart from the docking structure.

Abstract: Various aspects describe an information platform for consistently integrating and/or quantifying the underlying principles of ESG into financial analyses, analytical tools, metrics, and/or available information on reviewed companies, business entities, etc., and further provide integration of analysis with community-based insight, contextual information and tools for readily understanding both. Various embodiments implement machine learning tools for curating data sources and incorporating the data sources into the knowledge platform. The incorporation of AI moderated information sources enables succinct views of often massive information pools, and further provides for transitions between types of information (e.g., qualitative, quantitative, and interactive data source (e.g., engagements, collaborative information, etc.)).

Abstract: Disclosed herein are antisense compounds and methods for selectively reducing expression of an allelic variant of a huntingtin gene containing a single nucleotide polymorphism (SNP). Such methods, compounds, and composition are useful to treat, prevent, or ameliorate Huntington's Disease (HD).

Abstract: A slotted fishing blade for attaching to a fishing lure is disclosed. The blade includes a slot that opens from a lower outer edge and extends inwardly along a central longitudinal axis. The blade includes flaps extending from the outer edge that can be folded inwardly to secure a lure attachment element for securing a fishing lure to the plate. When a fishing lure is attached to the blade, the lure is free to move laterally along the lure attachment element. During retrieval of the slotted fishing blade attached to a fishing lure, the blade changes the performance of the lure, for example, by changing the flash, diving depth, or lure action, and/or by adding erratic motion, vibration, or oscillation. The slotted fishing blade may be used on a variety of lures, including hooks with natural baits such as worms or small bait fish.

Abstract: This invention is a system for coordinating unscheduled breaks for employees within a facility. In many professions, personnel are required to be in a certain area or at a certain location, but will often have the need to take an unscheduled break. The employee or personnel will then only be able to take the unscheduled break if she or he can find a substitute to take her or his place during the break. The system described and claimed herein allows for real-time coordination of unscheduled breaks in a work setting.

Abstract: This invention is a system for coordinating unscheduled breaks for employees within a facility. In many professions, personnel are required to be in a certain area or at a certain location, but will often have the need to take an unscheduled break. The employee or personnel will then only be able to take the unscheduled break if she or he can find a substitute to take her or his place during the break. The system described and claimed herein allows for real-time coordination of unscheduled breaks in a work setting.

Abstract: A tungsten rattle head used on fishing lures is used to attract and catch more fish. The present invention increases fishing performance by reducing bulk, eliminating protrusions, and reducing impediments while achieving a louder sound chamber. There are no rattling fishing lures that take advantage of placing one or more rattle elements in a tungsten body. Using a hollow chamber in a tungsten body allows one or more rattling elements to be added while keeping the size of the lure head small and more appealing to fish. The rattle elements click or rattle to attract fish to the bait during the cast and retrieve. By placing the rattle inside the head, there are no protrusions or impediments resulting in increased fish catching ability.

Abstract: Disclosed herein are antisense compounds and methods for selectively reducing expression of an allelic variant of a huntingtin gene containing a single nucleotide polymorphism (SNP). Such methods, compounds, and composition are useful to treat, prevent, or ameliorate Huntington's Disease (HD).

Abstract: To evaluate hypermonitoring of a patient, a processor controls an audiometer or computer software interface and executes instructions in a memory device which present various tones to the patient to determine a pitch match tone, a clinical loudness match, a subjective loudness and a subjective perceived loudness relative to the patient's tinnitus. A display and input device provide an interface between the processor and an operator.

Abstract: Disclosed herein are antisense compounds and methods for selectively reducing expression of an allelic variant of a huntingtin gene containing a single nucleotide polymorphism (SNP). Such methods, compounds, and composition are useful to treat, prevent, or ameliorate Huntington's Disease (HD).

Abstract: Methods and compositions for reducing expression of a mutant huntingtin (mHTT) protein in a cell are provided. Such methods include contacting the cell with an effective amount of a nucleic acid silencing agent targeting a differentiating polymorphism in RNA encoding the mHTT.

Abstract: Disclosed herein are antisense compounds and methods for selectively reducing expression of an allelic variant of a huntingtin gene containing a single nucleotide polymorphism (SNP). Such methods, compounds, and composition are useful to treat, prevent, or ameliorate Huntington's Disease (HD).

Abstract: Methods and compositions for reducing expression of a mutant huntingtin (mHTT) protein in a cell are provided. Such methods include contacting the cell with an effective amount of a nucleic acid silencing agent targeting a differentiating polymorphism in RNA encoding the mHTT.

Abstract: Disclosed herein are antisense compounds and methods for selectively reducing expression of an allelic variant of a huntingtin gene containing a single nucleotide polymorphism (SNP). Such methods, compounds, and composition are useful to treat, prevent, or ameliorate Huntington's Disease (HD).

Abstract: Methods and compositions for reducing expression of a mutant huntingtin (mHTT) protein in a cell are provided. Such methods include contacting the cell with an effective amount of a nucleic acid silencing agent targeting a differentiating polymorphism in RNA encoding the mHTT.