Patents by Inventor Jeffrey Charles Boehm

Jeffrey Charles Boehm has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • Oxazoles for treating cytokine mediated diseases
    Publication number: 20040106793
    Abstract: This invention relates to the novel oxazole compounds of Formula (I) and novel pharmaceutical compositions comprising a compound of Formula (I) and a pharmaceutically acceptable diluent or carrier.
    Type: Application
    Filed: July 9, 2003
    Publication date: June 3, 2004
    Applicant: SmithKline Beecham Corporation
    Inventors: Jerry Leroy Adams, Timothy Francis Gallagher, Jeffrey Charles Boehm, Susan Mary Thompson
  • Compounds of heteroaryl substituted imidazole, their pharmaceutical compositions and uses
    Patent number: 6730683
    Abstract: Novel 1,4,5-substituted imidazole compounds and compositions for use in therapy as cytokine inhibitors.
    Type: Grant
    Filed: June 10, 2002
    Date of Patent: May 4, 2004
    Assignee: SmithKline Beecham Corporation
    Inventors: Timothy Francis Gallagher, Jeffrey Charles Boehm, Jerry Leroy Adams
  • Compounds of heteroaryl substituted imidazole, their pharmaceutical compositions and uses
    Publication number: 20020198206
    Abstract: Novel 1,4,5-substituted imidazole compounds and compositions for use in therapy as cytokine inhibitors.
    Type: Application
    Filed: June 10, 2002
    Publication date: December 26, 2002
    Applicant: SmithKline Beecham Corporation
    Inventors: Timothy Francis Gallagher, Jeffrey Charles Boehm, Jerry Leroy Adams
  • Novel compounds
    Publication number: 20020188122
    Abstract: Novel 1, 4, 5- substituted imidazole compounds and compositions for use in therapy as cytokine inhibitors.
    Type: Application
    Filed: February 27, 2001
    Publication date: December 12, 2002
    Applicant: SmithKline Beecham Corporation
    Inventors: Jerry Leroy Adams, Peter William Sheldrake, Timothy Francis Gallagher, Ravi Shanker Garigipati, Paul Elliot Bender, Jeffrey Charles Boehm, Joseph Sisko, Zhi-Qiang Peng, John C. Lee
  • Oxazoles for treating cytokine mediated diseases
    Publication number: 20020169173
    Abstract: This invention relates to the novel oxazole compounds of Formula (I) and novel pharmaceutical compositions comprising a compound of Formula (I) and a pharmaceutically acceptable diluent or carrier.
    Type: Application
    Filed: January 25, 2001
    Publication date: November 14, 2002
    Applicant: SmithKline Beecham Corporation
    Inventors: Jerry Leroy Adams, Timothy Francis Gallagher, Jeffrey Charles Boehm, Susan Mary Thompson
  • Amino substituted pyrimidine containing compounds
    Patent number: 6369068
    Abstract: Novel 1,4,5-substituted imidazole compounds and compositions for use in therapy as cytokine inhibitors.
    Type: Grant
    Filed: June 11, 1999
    Date of Patent: April 9, 2002
    Assignee: Smithkline Beecham Corporation
    Inventors: Jerry Leroy Adams, Timothy Francis Gallagher, Irennegbe Kelly Osifo, Jeffrey Charles Boehm
  • compounds of heteroaryl substituted imidazole, their pharmaceutical compositons and uses
    Patent number: 6335340
    Abstract: Compounds of 1,4,5-substituted imidazole wherein one of the substituents can be a substituted pyrimidine, pyridazine or 1,2,4-triazine. These compounds and their pharmaceutical compositions are used in treating cytokine mediated diseases by inhibiting the production of IL-1 (interleukin-1), IL-8 (interleukin-8), and TNF (tumor necrosis factor).
    Type: Grant
    Filed: June 16, 2000
    Date of Patent: January 1, 2002
    Assignee: SmithKline Beecham Corporation
    Inventors: Timothy Francis Gallagher, Jeffrey Charles Boehm, Jerry Leroy Adams
  • Oxazoles for treating cytokine mediated diseases
    Patent number: 6288062
    Abstract: This invention relates to the novel oxazole compounds of Formula (I) and novel pharmaceutical compositions comprising a compound of Formula (I) and a pharmaceutically acceptable diluent or carrier. This invention also relates to a method of inhibiting cytokines and the treatment of cytokine mediated diseases, in mammals, thereby by administration of an effective amount of a compound according to Formula (I).
    Type: Grant
    Filed: December 20, 1999
    Date of Patent: September 11, 2001
    Assignee: SmithKline Beecham Corporation
    Inventors: Jerry Leroy Adams, Timothy Francis Gallagher, Jeffrey Charles Boehm, Susan Mary Thompson
  • Cycloalkyl substituted imidazoles
    Patent number: 6251914
    Abstract: Novel 1,4,5-substituted imidazole compounds and compositions for use in therapy.
    Type: Grant
    Filed: December 15, 1999
    Date of Patent: June 26, 2001
    Assignee: SmithKline Beecham Corporation
    Inventors: Jerry Leroy Adams, Jeffrey Charles Boehm, Ravi Shanker Garigipati, Margaret Sorenson
  • Process for making pyridyl and pyrimidine substituted imidazole compounds
    Patent number: 6218537
    Abstract: 1,4,5,-substituted imidazole compounds and compositions for use in therapy as cytokine inhibitors.
    Type: Grant
    Filed: May 13, 1998
    Date of Patent: April 17, 2001
    Assignee: SmithKline Beecham Corporation
    Inventors: Jerry Leroy Adams, Timothy Francis Gallagher, Joseph Sisko, Irennegbe Kelly Osifo, Jeffrey Charles Boehm
  • Compounds
    Patent number: 6150557
    Abstract: Novel 1, 4, 5-substituted imidazole compounds and compositions for use in therapy as cytokine inhibitors.
    Type: Grant
    Filed: November 3, 1998
    Date of Patent: November 21, 2000
    Assignee: SmithKline Beecham Corporation
    Inventors: Jerry Leroy Adams, Peter William Sheldrake, Timothy Francis Gallagher, Ravi Shanker Garigipati, Paul Elliot Bender, Jeffrey Charles Boehm, Joseph Sisko, Zhi-Qiang Peng, John C. Lee
  • Process of making tosylbenzyl formamide derivatives
    Patent number: 6103936
    Abstract: The present invention is to a novel process for the preparation of a compound of the formula: ##STR1## wherein p is 0, or 2;Ar is an optionally substituted phenyl or naphtyl; andinter alia R4 is an optionally susbtituted phenyl, naphth-1-yl, naphth-2-yl, or a heteroaryl ring;which process comprises reacting together an aldehyde of the formula:R.sub.4 --CHO;wherein R.sub.4 is as defined above;a compound of the formula:ArS(O)pH;wherein Ar, and p are as defined above;with formamide, an acid catalyst, and optionally a dehydrating agent.
    Type: Grant
    Filed: March 17, 1997
    Date of Patent: August 15, 2000
    Assignee: SmithKline Beecham Corporation
    Inventors: Jerry Leroy Adams, Peter William Sheldrake, Timothy Francis Gallagher, Ravishanker Garigipati, Paul Elliot Bender, Jeffrey Charles Boehm, Joseph Sisko, Zhi-Qiang Peng, John C. Lee
  • Amide compounds
    Patent number: 5969184
    Abstract: The present invention is directed to the novel intermediate compounds of the formula: ##STR1## wherein, interalia, R.sub.4 is a substituted phenyl or an optionally substituted napthyl derivative.
    Type: Grant
    Filed: May 9, 1997
    Date of Patent: October 19, 1999
    Assignee: SmithKline Beecham Corporation
    Inventors: Jerry Leroy Adams, Peter William Sheldrake, Timothy Francis Gallagher, Ravi Shanker Garigipati, Paul Elliot Bender, Jeffrey Charles Boehm, Joseph Sisko, Zhi-Qiang Peng, John C. Lee
  • Process of preparing imidazole compounds
    Patent number: 5869660
    Abstract: Novel 1,4,5-substituted imidazole compounds and compositions for use in therapy as cytokine inhibitors.
    Type: Grant
    Filed: January 23, 1998
    Date of Patent: February 9, 1999
    Assignee: SmithKline Beecham Corporation
    Inventors: Jerry Leroy Adams, Timothy Francis Gallagher, Joseph Sisko, Zhi Qiang Peng, Irennegbe Kelly Osifo, Jeffrey Charles Boehm
  • Imidazole compounds and compositions
    Patent number: 5739143
    Abstract: Novel 1,4,5-substituted imidazole compounds and compositions for use in therapy as cytokine inhibitors.
    Type: Grant
    Filed: December 11, 1996
    Date of Patent: April 14, 1998
    Assignee: SmithKline Beecham Corporation
    Inventors: Jerry Leroy Adams, Timothy Francis Gallagher, Joseph Sisko, Zhi Qiang Peng, Irennegbe Kelly Osifo, Jeffrey Charles Boehm
  • Pyridyl imidazole compounds and compositions
    Patent number: 5670527
    Abstract: Novel 1, 4, 5-substituted imidazole compounds and compositions for use in therapy as cytokine inhibitors.
    Type: Grant
    Filed: June 7, 1995
    Date of Patent: September 23, 1997
    Assignee: SmithKline Beecham Corporation
    Inventors: Jerry Leroy Adams, Ravi Shanker Garigipati, Jeffrey Charles Boehm
  • Imidazole compounds, compositions and use
    Patent number: 5658903
    Abstract: Novel 1,4,5-substituted imidazole compounds and compositions for use in therapy as cytokine inhibitors.
    Type: Grant
    Filed: June 3, 1996
    Date of Patent: August 19, 1997
    Assignee: SmithKline Beecham Corporation
    Inventors: Jerry Leroy Adams, Timothy Francis Gallagher, Joseph Sisko, Zhi-Qiang Peng, Irennegbe Kelly Osifo, Jeffrey Charles Boehm