Patents by Inventor Jeffrey Charles White

Jeffrey Charles White has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • Cytotoxicity test method for medical devices
    Patent number: 11378570
    Abstract: A cytotoxicity method for medical devices that has equivalent sensitivity, and greater efficiency compared to the colony formation assay (CFA) direct contact method is developed. The quantitative, direct contact cytotoxicity test method uses Mouse lymphoma TK or human lymphoblastoid TK6 suspension cells for medical device safety assessment. The advantages of using the suspension cell assay over adherent V79-4 cells is that this approach is quantitative, automated, not susceptible to potential mechanical damage imparted by the overlying test materials, and avoids issues related to non-adherence of cells to the test material which might impact the interpretation of test results.
    Type: Grant
    Filed: May 24, 2018
    Date of Patent: July 5, 2022
    Assignee: Alcon Inc.
    Inventors: Xuemei Liu, Fan Zhang, Denise P. Rodeheaver, Ann Marie Wright, Charlon Tolliver, Jamie Michaelis Walker, Robert Edward Rose, Stephen Paul Shannon, Jeffrey Charles White
  • Cytotoxicity Test Method for Medical Devices
    Publication number: 20180348205
    Abstract: A cytotoxicity method for medical devices that has equivalent sensitivity, and greater efficiency compared to the colony formation assay (CFA) direct contact method is developed. The quantitative, direct contact cytotoxicity test method uses Mouse lymphoma TK or human lymphoblastoid TK6 suspension cells for medical device safety assessment. The advantages of using the suspension cell assay over adherent V79-4 cells is that this approach is quantitative, automated, not susceptible to potential mechanical damage imparted by the overlying test materials, and avoids issues related to non-adherence of cells to the test material which might impact the interpretation of test results.
    Type: Application
    Filed: May 24, 2018
    Publication date: December 6, 2018
    Inventors: Xuemei Liu, Fan Zhang, Denise P. Rodeheaver, Ann Marie Wright, Charion Tolliver, Jamie Michaelis Walker, Robert Edward Rose, Stephen Paul Shannon, Jeffrey Charles White