Abstract: A fluid handling system for use in bodily fluid analysis. The system comprises a first fluid handling module configured to interface with a main instrument. The first fluid handling module has a first fluid handling network and the first fluid handling network includes an infusate passage and an infusion fluid pressure member suitable for moving fluid within the infusate passage. The fluid handling system also has a second fluid handling module separate from the first module which is configured to interface with the main instrument. The second fluid handling module has a second fluid handling network and at least one sample analysis cell which is accessible via the second fluid handling network. The first and second modules are configured to interconnect and provide fluid communication between the first and second fluid handling network and the sample cells.

Abstract: A fluid handling system for use in bodily fluid analysis. The system comprises a first fluid handling module configured to interface with a main instrument. The first fluid handling module has a first fluid handling network and the first fluid handling network includes an infusate passage and an infusion fluid pressure member suitable for moving fluid within the infusate passage. The fluid handling system also has a second fluid handling module separate from the first module which is configured to interface with the main instrument. The second fluid handling module has a second fluid handling network and at least one sample analysis cell which is accessible via the second fluid handling network. The first and second modules are configured to interconnect and provide fluid communication between the first and second fluid handling network and the sample cells.

Abstract: A fluid handling system for use in bodily fluid analysis. The system comprises a first fluid handling module configured to interface with a main instrument. The first fluid handling module has a first fluid handling network and the first fluid handling network includes an infusate passage and an infusion fluid pressure member suitable for moving fluid within the infusate passage. The fluid handling system also has a second fluid handling module separate from the first module which is configured to interface with the main instrument. The second fluid handling module has a second fluid handling network and at least one sample analysis cell which is accessible via the second fluid handling network. The first and second modules are configured to interconnect and provide fluid communication between the first and second fluid handling network and the sample cells.

Abstract: A fluid handling system for use in bodily fluid analysis. The system comprises a first fluid handling module configured to interface with a main instrument. The first fluid handling module has a first fluid handling network and the first fluid handling network includes an infusate passage and an infusion fluid pressure member suitable for moving fluid within the infusate passage. The fluid handling system also has a second fluid handling module separate from the first module which is configured to interface with the main instrument. The second fluid handling module has a second fluid handling network and at least one sample analysis cell which is accessible via the second fluid handling network. The first and second modules are configured to interconnect and provide fluid communication between the first and second fluid handling network and the sample cells.

Abstract: A fluid handling system for use in bodily fluid analysis. The system comprises a first fluid handling module configured to interface with a main instrument. The first fluid handling module has a first fluid handling network and the first fluid handling network includes an infusate passage and an infusion fluid pressure member suitable for moving fluid within the infusate passage. The fluid handling system also has a second fluid handling module separate from the first module which is configured to interface with the main instrument. The second fluid handling module has a second fluid handling network and at least one sample analysis cell which is accessible via the second fluid handling network. The first and second modules are configured to interconnect and provide fluid communication between the first and second fluid handling network and the sample cells.

Abstract: A thin film composite membrane comprises a core layer and a sheath UV-crosslinked polymer layer. The thin film composite membrane is produced by the co-extrusion of two polymer solutions. The core layer and the sheath layer can be separately optimized. The sheath layer may be UV-crosslinked to provide stability and selectivity at the desired operating temperature of the composite membrane.

Abstract: A gas separation membrane comprises a blend of polyethersulfone (PES) and aromatic polyimide polymers that may comprise a plurality of first repeating units of formula (I), wherein X1, X 2 and X3 are herein defined.

Abstract: A gas separation membrane comprises a blend of polyethersulfone (PES) and aromatic polyimide polymers that may comprise a plurality of first repeating units of formula (I), wherein X1, X 2 and X3 are herein defined.

Abstract: A thin film composite membrane comprises a core layer and a sheath UV-crosslinked polymer layer. The thin film composite membrane is produced by the co-extrusion of two polymer solutions. The core layer and the sheath layer can be separately optimized. The sheath layer may be UV-crosslinked to provide stability and selectivity at the desired operating temperature of the composite membrane.

Abstract: Disclosed are systems, apparatus and methods for determining information related to analyte(s) (e.g., concentration) in a sample such as biological fluid. An analysis system for determining information relating to at least one analyte in a sample of biological fluid can be configured to: withdraw the sample of biological fluid from the source of biological fluid; interrupt the flow of infusion fluid while the sample of biological fluid is withdrawn; analyze the withdrawn biological fluid to determine information relating to at least one analyte; and resume the flow of infusion fluid after the sample of biological fluid is withdrawn. A method of interrupting flow of an infusion fluid without triggering an alarm can comprise, while the flow of the infusion fluid is interrupted, diverting the flow of the infusion fluid from a fluid passageway to an expandable volume at a rate that maintains constant flow from an infusion pump.

Abstract: A method of extracting and analyzing bodily fluids from a patient at the point of care for the patient is provided. The method comprises establishing fluid communication between an analyte detection system and a bodily fluid in the patient. A portion of the bodily fluid is drawn from the patient. A first component of the bodily fluid is separated from the drawn portion, while the analyte detection system remains in fluid communication with the patient. The analyte detection system analyzes the first component to measure a concentration of an analyte in an accurate and timely manner.