Abstract: A lamp body to be releasably coupled to a mounting surface. The lamp body comprises a mount post and a cantilevered lock. The mount post is configured to be received in a mounting hole in the mounting surface, where the mount post is configured to slide between a releasing portion of the mounting hole and a locking portion of the mounting hole. The cantilevered lock is configured to releasably engage with a stop on the mounting surface when the mount post slides into the locking portion of the mounting hole to retain the mount post within the locking portion of the mounting hole.

Abstract: A device having an inner surface with a combination of reflective and refractive surface facets swept about an axis of revolution perpendicular to the optical axis of the device. The outer surface has a non-planar, non-circular, non-spherical shape. This outer surface generates an appropriate intensity distribution in a direction generally parallel to the major axis of the output rectangle and may also distribute energy generally parallelly to the minor axis of the output rectangle as well.

Abstract: A device for creating a predetermined light output distribution having a substantially rectangular shape in angle space is provided having a lens with a revolved inner surface and a complex outer surface. The inner surface has a combination of reflective and refractive surface facets swept about an axis of revolution perpendicular to the optical axis of the device. The outer surface has a non-planar, non-circular, non-spherical shape. This outer surface generates an appropriate intensity distribution in a direction generally parallel to the major axis of the output rectangle and may also distribute energy generally parallelly to the minor axis of the output rectangle as well. The optical efficiency improvement in the design of this improved preferably LED-based product has several direct benefits including; increased reliability, lower operating temperature, reduced electrical requirements, greater product life and significantly reduced cost as compared to existing LED products.

Abstract: The present invention provides compounds of formula (I): and pharmaceutically acceptable salts thereof, wherein R1, R2, R3, R4, R5, R6, R7, R8, m and n are defined as described herein. The invention also provides methods of making the compounds of formula (I), and methods of treating inflammatory diseases, such as rheumatoid arthritis, in a mammal comprising administering a therapeutically effective amount of a compound of formula (I) to the mammal.

Abstract: This invention provides compounds of Formula I, having the structure: that are useful in treating diseases or disorders mediated by TNF-?, such as arthritis (rheumatoid arthritis (RA), juvenile RA, psoriatic arthritis, osteoarthritis etc), tumor metastasis, tissue ulceration, abnormal wound healing, periodontal disease, bone disease, diabetes (insulin resistance) and HIV infection, ankylosing spondylitis, psoriasis, sepsis, multiple sclerosis, Crohn's disease, degenerative cartilage loss, asthma, idiopathic pulmonary fibrosis, vasculitis, systemic lupus erythematosus, irritable bowel syndrome, acute coronary syndrome, hepatitis C, cachexia, COPD, stroke or type 2 diabetes, and for alleviation of symptoms thereof. The invention further provides methods for use of the compounds.

Abstract: The present invention provides an azolylacylquanidine compound of formula I The present invention also provides methods for the use thereof to inhibit ?-secretase (BACE) and treat ?-amyloid deposits and neurofibrillary tangles.

Abstract: The present invention provides an amino-pyridine compound of formula I The present invention also provides methods for the use thereof to inhibit ?-secretase (BACE) and treat ?-amyloid deposits and neurofibrillary tangles.