Patents by Inventor Jeffrey D. Bornstein

Jeffrey D. Bornstein has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • THERAPEUTIC AND DIAGNOSTIC METHODS RELATED TO LYSYL OXIDASE-LIKE 2 (LOXL2)
    Publication number: 20170327595
    Abstract: Provided are therapeutic, diagnostic, and prognostic methods for disease, including diseases associated with fibrosis and cancer using agents that bind to, inhibit, and/or detect lysyl oxidase-like 2 (LOXL2), and agents, compositions, kits, assay systems, and devices for use with such methods.
    Type: Application
    Filed: January 26, 2017
    Publication date: November 16, 2017
    Inventors: Jeffrey D. Bornstein, Joanne I. Adamkewicz, Victoria Smith, Susan K. Lyman, Jason Chien, Xiaoming Li, Lixin Shao
  • LYSYL OXIDASE-LIKE 2 ASSAY AND METHODS OF USE THEREOF
    Publication number: 20170269085
    Abstract: The present disclosure provides an assay to detect and/or quantify circulating lysyl oxidase-like 2 (LOXL2) polypeptides in an individual. The assay is useful in diagnostic and prognostic applications, which are also provided.
    Type: Application
    Filed: December 1, 2016
    Publication date: September 21, 2017
    Inventors: Victoria Smith, Joanne I. Adamkewicz, Susan K. Lyman, Jason Chien, Xiaoming Li, Lixin Shao, Jeffrey D. Bornstein
  • METHODS OF TREATING LIVER DISEASE
    Publication number: 20150342943
    Abstract: The present disclosure relates to a method of preventing and/or treating liver disease comprising administering an ASK1 inhibitor, optionally in combination with a LOXL2 inhibitor, to a patient in need thereof.
    Type: Application
    Filed: May 29, 2015
    Publication date: December 3, 2015
    Inventors: Jeffrey D. Bornstein, David Breckenridge, Satyajit Karnik, Victoria Smith, Daniel B. Tumas
  • LYSYL OXIDASE-LIKE 2 ASSAY AND METHODS OF USE THEREOF
    Publication number: 20140206017
    Abstract: The present disclosure provides an assay to detect and/or quantify circulating lysyl oxidase-like 2 (LOXL2) poly-peptides in an individual. The assay is useful in diagnostic and prognostic applications, which are also provided.
    Type: Application
    Filed: June 1, 2012
    Publication date: July 24, 2014
    Inventors: Victoria Smith, Joanne I. Adamkewicz, Susan K. Lyman, Jason Chien, Xiaoming Li, Lixin Shao, Jeffrey D. Bornstein
  • THERAPEUTIC AND DIAGNOSTIC METHODS RELATED TO LYSYL OXIDASE-LIKE 2 (LOXL2)
    Publication number: 20140120102
    Abstract: Provided are therapeutic, diagnostic, and prognostic methods for disease, including diseases associated with fibrosis and cancer using agents that bind to, inhibit, and/or detect lysyl oxidase-like 2 (LOXL2), and agents, compositions, kits, assay systems, and devices for use with such methods.
    Type: Application
    Filed: October 30, 2013
    Publication date: May 1, 2014
    Applicant: Gilead Sciences, Inc.
    Inventors: Jeffrey D. BORNSTEIN, Joanne I. ADAMKEWICZ, Victoria SMITH, Susan K. LYMAN, Jason CHIEN, Xiaoming LI, Lixin SHAO
  • LYSYL OXIDASE-LIKE 2 ASSAY AND METHODS OF USE THEREOF
    Publication number: 20120309020
    Abstract: The present disclosure provides an assay to detect and/or quantify circulating lysyl oxidase-like 2 (LOXL2) polypeptides in an individual. The assay is useful in diagnostic and prognostic applications, which are also provided.
    Type: Application
    Filed: June 1, 2012
    Publication date: December 6, 2012
    Applicant: Gilead Biologics, Inc.
    Inventors: Victoria Smith, Joanne I. Adamkewicz, Susan K. Lyman, Jason Chien, Xiaoming Li, Lixin Shao, Jeffrey D. Bornstein