Patents by Inventor Jeffrey D. Fischer
Jeffrey D. Fischer has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).
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Publication number: 20240123055Abstract: The invention relates to compositions and peptides or peptide sequences that induce an immune response in an animal or a mammal that is protective against infection by one or more pathogens. In addition, the invention relates to immunogenic composition and vaccines comprising compositions and peptide sequences and to method for treating and preventing an infection in animals and mammals such as humans and antibodies.Type: ApplicationFiled: October 16, 2023Publication date: April 18, 2024Applicant: Longhorn VAccines and Diagnostics, LLCInventors: Gerald W. Fischer, Clara J. Sei, Jeffrey D. Fischer
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Publication number: 20240091331Abstract: The invention relates to compositions and peptides or peptide sequences that induce an immune response in an animal or a mammal that is protective against infection by one or more pathogens. In addition, the invention relates to immunogenic composition and vaccines comprising compositions and peptide sequences and to method for treating and preventing an infection in animals and mammals such as humans and antibodies.Type: ApplicationFiled: November 13, 2023Publication date: March 21, 2024Applicant: Longhorn Vaccines and Diagnostics, LLCInventors: Gerald W. Fischer, Clara J. Sei, Jeffrey D. Fischer
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Publication number: 20240050552Abstract: The invention is directed to immunogenic compositions and method of treatment comprising a peptide or nucleic acid that encodes the peptide that induces an immune response in a mammal that is protective against infection by one or more pathogens. The peptide sequence contains multiple epitopes, wherein at least one epitope is a composite epitope which is a combination of two or more conserved epitopes of the pathogen wherein the amino acid sequence of the composite is not an amino acid sequence of the pathogen. In addition, the invention is directed to vaccines comprising the peptide or nucleic acid that encodes the peptide for treating and preventing an infection in mammals such as animals and humans.Type: ApplicationFiled: August 8, 2023Publication date: February 15, 2024Applicant: Longhorn Vaccines and Diagnostics, LLCInventors: Jeffrey D. Fischer, Clara J. Sei, Gerald W. Fischer
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Publication number: 20230226166Abstract: The invention relates to immunogenic compositions comprising an antigen obtained or derived from an antigenic epitope of one or more pathogens that induces an immune response in a mammal, an antigen obtained or derived from bacterial cell wall or viral material that induces an immune response in a mammal such as LTA, PNG or LPS, and a T cell stimulating antigen such as CRM. Preferably the immunogenic composition is a vaccine that is effective against a pathogenic infection or can generate antibodies that can be collected that are protective against infection by the pathogen. In addition, the invention relates to vaccines comprising antigens and to method for treating and preventing an infection.Type: ApplicationFiled: January 31, 2023Publication date: July 20, 2023Applicant: Longhorn Vaccines and Diagnostics, LLCInventors: Jeffrey D. Fischer, Clara J. Sei, Gerald W. Fischer
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Publication number: 20220296696Abstract: The invention relates to composite antigens comprising an antigen obtained or derived from an antigenic epitope of one or more pathogens that induces an immune response in a mammal, an antigen obtained or derived from bacterial cell wall material that induces an immune response in a mammal such as LTA, PNG or LPS, and a T cell stimulating antigen such as CRM. Preferably the composite antigen comprises an immunogenic composition or a vaccine that is effective against the pathogen or can generate antibodies that can be collected that are protective against infection by the pathogen. In addition, the invention relates to vaccines comprising composite antigens and to method for treating and preventing an infection.Type: ApplicationFiled: October 20, 2021Publication date: September 22, 2022Applicant: Longhorn Vaccines and Diagnostics, LLCInventors: Jeffrey D. Fischer, Clara J. Sei, Luke T. Daum, Gerald W. Fischer
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Publication number: 20220118079Abstract: The invention relates to composite antigens comprising an antigen obtained or derived from an antigenic epitope of one or more pathogens that induces an immune response in a mammal, an antigen obtained or derived from bacterial cell wall material that induces an immune response in a mammal such as LTA, PNG or LPS, and a T cell stimulating antigen such as CRM. Preferably the composite antigen comprises an immunogenic composition or a vaccine that is effective against the pathogen or can generate antibodies that can be collected that are protective against infection by the pathogen. In addition, the invention relates to vaccines comprising composite antigens and to method for treating and preventing an infection.Type: ApplicationFiled: October 20, 2021Publication date: April 21, 2022Applicant: Longhorn Vaccines and Diagnostics, LLCInventors: Jeffrey D. Fischer, Clara J. Sei, Luke T. Daum, Gerald W. Fischer
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Patent number: 11041216Abstract: The invention is directed to compositions and methods for rapidly detecting, amplifying, and quantitating one or more pathogen-specific nucleic acids in a biological sample, and in particular, samples obtained from patients with sepsis. The invention also provides diagnostic kits containing specific amplification primers, and labeled detection probes that specifically bind to the amplification products obtained therefrom. The invention is also directed to detecting the quantity or ratio of genomic sequences and mRNA sequences of an individual suspected of being infected with an infectious agent over time to assess the progress of the infection over time. Also disclosed are compositions and methods for the isolation and characterization of nucleic acids that are specific to one or more pathogens, such as, for example, Influenza virus, Mycobacterium tuberculosis, Plasmodium, and/or HIV from a wide variety of samples including those of biological, environmental, clinical and/or veterinary origin.Type: GrantFiled: November 25, 2016Date of Patent: June 22, 2021Assignee: Longhorn Vaccines and Diagnostics, LLCInventors: Jeffrey D. Fischer, Luke T. Daum, Gerald W. Fischer
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Publication number: 20170073738Abstract: The invention is directed to compositions and methods for rapidly detecting, amplifying, and quantitating one or more pathogen-specific nucleic acids in a biological sample, and in particular, samples obtained from patients with sepsis. The invention also provides diagnostic kits containing specific amplification primers, and labeled detection probes that specifically bind to the amplification products obtained therefrom. The invention is also directed to detecting the quantity or ratio of genomic sequences and mRNA sequences of an individual suspected of being infected with an infectious agent over time to assess the progress of the infection over time. Also disclosed are compositions and methods for the isolation and characterization of nucleic acids that are specific to one or more pathogens, such as, for example, Influenza virus, Mycobacterium tuberculosis, Plasmodium, and/or HIV from a wide variety of samples including those of biological, environmental, clinical and/or veterinary origin.Type: ApplicationFiled: November 25, 2016Publication date: March 16, 2017Applicant: Longhorn Vaccines and Diagnostics, LLCInventors: Jeffrey D. Fischer, Luke T. Daum, Gerald W. Fischer
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Patent number: 9308141Abstract: The invention is directed to a mobile medical facility capable of treating, diagnosing and performing minor surgery on multiple patients at one time. In general, the facility includes a health care area which is interchangeable between a first transportable configuration and a second, operational configuration. In the operational configuration, the health care area is expanded and capable of providing general care or diagnostic facilities to multiple patients as well as registration, counseling and triage to at least one patient. Preferable a row of patient treatment bays are provided with intake, counseling and triage cubicles and storage areas.Type: GrantFiled: May 8, 2014Date of Patent: April 12, 2016Assignee: Med1 Partners, LLCInventors: Thomas H. Blackwell, Timothy J. Masud, Jeffrey D. Fischer
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Publication number: 20140246876Abstract: The invention is directed to a mobile medical facility capable of treating, diagnosing and performing minor surgery on multiple patients at one time. In general, the facility includes a health care area which is interchangeable between a first transportable configuration and a second, operational configuration. In the operational configuration, the health care area is expanded and capable of providing general care or diagnostic facilities to multiple patients as well as registration, counseling and triage to at least one patient. Preferable a row of patient treatment bays are provided with intake, counseling and triage cubicles and storage areas.Type: ApplicationFiled: May 8, 2014Publication date: September 4, 2014Applicant: Med1 Partners, LLCInventors: Thomas H. Blackwell, Timothy J. Masud, Jeffrey D. Fischer
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Patent number: 8733813Abstract: The invention is directed to a mobile medical facility capable of treating, diagnosing and performing minor surgery on multiple patients at one time. In general, the facility includes a health care area which is interchangeable between a first transportable configuration and a second, operational configuration. In the operational configuration, the health care area is expanded and capable of providing general care or diagnostic facilities to multiple patients as well as registration, counseling and triage to at least one patient. Preferable a row of patient treatment bays are provided with intake, counseling and triage cubicles and storage areas.Type: GrantFiled: November 20, 2012Date of Patent: May 27, 2014Assignee: Med 1 Partners, LLCInventors: Thomas H. Blackwell, Timothy J. Masud, Jeffrey D. Fischer