Patents by Inventor Jeffrey D. Lifson

Jeffrey D. Lifson has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • Method of selectively inhibiting HIV
    Patent number: 4869903
    Abstract: A method of inhibiting HIV replication in and cellular proliferation of HIV-infected cells. The infected cells are exposed to a single-chain ribosome inactivating protein, at a protein concentration and for an exposure period sufficient to produce a substantial reduction in (a) the level of HIV antigen or reverse transcriptase associated with the infected cells, (b) the ratio of viability of infected/uninfected T cells, and/or (c) the ratio of HIV antigen/cellular antigen in infected macrophages. The method is used to treat HIV infection in humans.
    Type: Grant
    Filed: April 8, 1988
    Date of Patent: September 26, 1989
    Assignee: Genelabs Incorporated
    Inventors: Jeffrey D. Lifson, Michael S. McGrath, Hin-Wing Yeung, Kuo Hwang
  • Method of inhibiting HIV
    Patent number: 4795739
    Abstract: A method of inhibiting expression of HIV antigens in human blood cells infected with HIV. The infected cells are exposed to a plant protein or glycoprotein, such as trichosanthin or momorcharin, at a concentration sufficient to (a) produce a substantial reduction in the level of HIV antigen, and (b) effect a selective reduction in the number of HIV-infected cells, with respect to uninfected cells of the same type. The method is used to treat HIV infection in humans. In another aspect, the invention includes a method of screening drug agents effective in treating HIV infection in humans.
    Type: Grant
    Filed: May 29, 1987
    Date of Patent: January 3, 1989
    Assignees: Gene Labs, Inc., Regents of University of California
    Inventors: Jeffrey D. Lifson, Michael S. McGrath, Hin-Wing Yeung, Kou M. Hwang