Patents by Inventor Jeffrey D. Manklis

Jeffrey D. Manklis has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • METHODS AND SYSTEMS OF MOLECULAR RECORDING BY CRISPR-CAS SYSTEM
    Publication number: 20210230588
    Abstract: This invention provides methods of altering a cell including providing the cell with a nucleic acid sequence encoding a Cas1 protein and/or a Cas2 protein of a CRISPR adaptation system, providing the cell with a CRISPR array nucleic acid sequence including a leader sequence and at least one repeat sequence, wherein the cell expresses the Cas1 protein and/or the Cas2 protein and wherein the CRISPR array nucleic acid sequence is within genomic DNA of the cell or on a plasmid. Also provided are methods and systems for nucleic acid storage and in vivo molecular recordings of events into a cell.
    Type: Application
    Filed: February 16, 2017
    Publication date: July 29, 2021
    Inventors: George M. Church, Seth Lawler Shipman, Jeffrey D. Manklis, Jeffrey Matthew Nivala