Patents by Inventor Jeffrey D. Rimer
Jeffrey D. Rimer has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).
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Patent number: 12024452Abstract: Analogues of citrate, namely hydroxycitrate (HCA) and isocitrate (ICA), have dual roles as nucleation inhibitors and growth suppressors in the formation of mineral scale. Their potency is comparable to commercial phosphorous-based inhibitors, but they are more environmentally friendly, which has practical advantages for use in a broad range of commercial applications.Type: GrantFiled: August 1, 2022Date of Patent: July 2, 2024Assignee: UNIVERSITY OF HOUSTON SYSTEMInventors: Jeffrey D. Rimer, Xi Geng, Ricardo Sosa
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Publication number: 20240173705Abstract: Interconnected zeolite nanosheets with a structural motif resembling self-pillared pentasil zeolites are synthesized through the use of MEL or MFI-type zeolites as crystalline seeds. The use of MEL- or MFI-type zeolites as crystalline seeds induces the spontaneous formation of pillared zeolites, thus avoiding, for the first time, the use of any organic or branching template for the crystallization of these hierarchical structures.Type: ApplicationFiled: February 16, 2022Publication date: May 30, 2024Applicant: University of Houston SystemInventors: Jeffrey D. Rimer, Rishabh Jain
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Patent number: 11866325Abstract: The methods for synthesizing mordenite (MOR) zeolite crystals described herein utilize a combination of organics and produce MOR crystals with reduced size, higher Si/Al ratio, fewer stacking faults, less occluded organics in the final product, and a longer catalyst lifetime.Type: GrantFiled: May 15, 2019Date of Patent: January 9, 2024Assignee: UNIVERSITY OF HOUSTON SYSTEMInventors: Jeffrey D. Rimer, Manjesh Kumar
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Publication number: 20230399234Abstract: Nano-sized zeolites may be prepared using germanium oxide (GeO2) as a component of the overall synthesis composition. This is accomplished by the addition of GeO2 as an inexpensive reagent for the synthesis gel. Most of the Ge is retained in the synthesis mixture and the small amount incorporated in the zeolite solid (Si/Ge>100) does not have an appreciable impact on zeolite acidity or other physicochemical properties. The methods disclosed herein circumvent challenges to prepare nano-sized zeolites having dimensions less than 100 nm.Type: ApplicationFiled: June 14, 2023Publication date: December 14, 2023Applicant: University of Houston SystemInventors: Jeffrey D. Rimer, Deependra Parmar, Adam Mallette
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Publication number: 20230077288Abstract: A secondary growth procedure described herein is used to prepare finned zeolites. The finned zeolites possess properties that are distinctly unique compared to crystals of similar size lacking fins. The procedure is amenable to a wide range of zeolite crystal structures.Type: ApplicationFiled: February 9, 2021Publication date: March 9, 2023Applicant: University of Houston SystemInventors: Jeffrey D. Rimer, Yufeng Shen, Heng Dai
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Publication number: 20230030968Abstract: Analogues of citrate, namely hydroxycitrate (HCA) and isocitrate (ICA), have dual roles as nucleation inhibitors and growth suppressors in the formation of mineral scale. Their potency is comparable to commercial phosphorous-based inhibitors, but they are more environmentally friendly, which has practical advantages for use in a broad range of commercial applications.Type: ApplicationFiled: August 1, 2022Publication date: February 2, 2023Applicant: University of Houston SystemInventors: Jeffrey D. Rimer, Xi Geng, Ricardo Sosa
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Publication number: 20210214237Abstract: The methods for synthesizing mordenite (MOR) zeolite crystals described herein utilize a combination of organics and produce MOR crystals with reduced size, higher Si/Al ratio, fewer stacking faults, less occluded organics in the final product, and a longer catalyst lifetime.Type: ApplicationFiled: May 15, 2019Publication date: July 15, 2021Applicant: University of Houston SystemInventors: Jeffrey D. Rimer, Manjesh Kumar
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Patent number: 10662070Abstract: Embodiments of the invention generally provide compositions of crystalline zeolite materials with tailored crystal habits and the methods for forming such crystalline zeolite materials. The methods for forming the crystalline zeolite materials include binding one or more zeolite growth modifiers (ZGMs) to the surface of a zeolite crystal, which results in the modification of crystal growth rates along different crystallographic directions, leading to the formation of zeolites having a tailored crystal habit. The improved properties enabled by the tailored crystal habit include a minimized crystal thickness, a shortened internal diffusion pathlength, and a greater step density as compared to a zeolite having the native crystal habit prepared by traditional processes. The tailored crystal habit provides the crystalline zeolite materials with an aspect ratio of about 4 or greater and crystal surfaces having a step density of about 25 steps/?m2 or greater.Type: GrantFiled: November 8, 2018Date of Patent: May 26, 2020Assignee: UNIVERSITY OF HOUSTON SYSTEMInventors: Jeffrey D. Rimer, Manjesh Kumar
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Publication number: 20200009163Abstract: Embodiments described herein generally relate to compositions and methods requiring these compositions that may act to reduce the incidence and/or reoccurrence of kidney stones and/or other pathological calcification diseases, symptoms, or conditions. The compositions include a polyphosphate material, which may be method of treating pathological calcification. In some embodiments, the polyphosphate material included in the composition to be administered may be a linear tripolyphosphate material or a hexametaphosp hate material.Type: ApplicationFiled: March 6, 2018Publication date: January 9, 2020Applicant: UNIVERSITY OF HOUSTON SYSTEMInventors: Jeffrey D. Rimer, Bryan G. Alamani
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Patent number: 10421666Abstract: Methods of controlling crystal polymorphism in organic-free synthesis of Na-Zeolites and the zeolite crystals formed using those methods are provided. The methods disclosed herein create certain types of zeolite crystals more efficiently than other previously known methods. The methods also create certain types of zeolite crystals in a form and concentration not previously disclosed. The methods disclosed herein generally comprise using solutions with varying ratios of silicon (Si), aluminum (Al), hydroxide (OH), and water. Some implementations of the invention disclosed include efficient methods of producing nearly pure cancrinite (CAN), methods of obtaining sodalite in solutions with a high Si/Al ratio, and a method of forming thin, platelet-like ANA crystals with a width of less than about 1 ?m and a length of at least about 3 ?m.Type: GrantFiled: June 21, 2017Date of Patent: September 24, 2019Assignee: UNIVERSITY OF HOUSTON SYSTEMInventors: Jeffrey D. Rimer, Miguel Maldonado, Matthew D. Oleksiak
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Patent number: 10407312Abstract: In an embodiment, the present disclosure pertains to a composition comprising a zeolite with high silica content. In some embodiments, the silica to aluminum ratio (SAR) for the zeolite is 2:1. In some embodiments, the zeolite comprises Zeolite HOU-2 (LTA-type). In some embodiments, the silica to aluminum ratio (SAR) for the zeolite is >3. In some embodiments, the zeolite comprises Zeolite HOU-3 (FAU type). In some embodiments, the zeolite is synthesized using a one-step method. In some embodiments, the zeolite is synthesized without the use of an organic structure-directing agent (OSDA). In some embodiments, the zeolite is synthesized without the use of post-synthesis dealumination. In some embodiments, the zeolite is synthesized without the use crystal seeds. In some embodiments, the zeolite is used in commercial ion exchange. In some embodiments, the zeolite is used for catalysis reaction. In some embodiments, the zeolite is highly thermostable.Type: GrantFiled: September 17, 2015Date of Patent: September 10, 2019Assignee: UNIVERSITY OF HOUSTON SYSTEMInventors: Marlon T. Conato, Matthew D. Oleksiak, Jeffrey D. Rimer
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Publication number: 20190216756Abstract: In an embodiment of the present disclosure, there is provided a composition for dissolving calcium oxalate crystals thereby inhibiting/preventing further growth of crystals. In some embodiments, such a composition comprises at least one stereoisomer of hydroxycitrate, a derivative of the organic acid citrate. Such a method comprises administering to the subject an effective amount of the aforementioned composition. In another embodiment, the present disclosure pertains to a method of treating kidney stone disorder. Such a method comprises administering to a subject in need thereof a therapeutically effective amount of the aforementioned composition. In yet another embodiment, the present disclosure relates to a method of treating calcium oxalate stone disease. In an embodiment, the method comprises administering to a subject in need thereof a therapeutically effective amount of the aforementioned composition.Type: ApplicationFiled: March 27, 2019Publication date: July 18, 2019Applicant: University of Houston SystemInventors: Jeffrey D. Rimer, Jihae Chung, John Asplin
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Publication number: 20190153035Abstract: In an embodiment, the present disclosure pertains to a composition for inhibiting calcium oxalate monohydrate crystal growth comprising at least one isolated polypeptide comprising a plurality of amino acids that bind the surface of the calcium oxalate monohydrate crystal; and a plurality of amino acids spacers, wherein the amino acid spacers are arranged in varying sequences between the plurality of amino acids that bind the surface of the calcium oxalate monohydrate crystal. In some embodiments, the present disclosure related to a method of controlling calcium oxalate monohydrate crystal growth in a subject in need thereof comprising administering to the subject therapeutically effective amount of the calcium oxalate monohydrate inhibiting polypeptide. In some embodiments, the present disclosure relates to a method of identifying calcium oxalate monohydrate inhibiting peptides.Type: ApplicationFiled: February 1, 2019Publication date: May 23, 2019Inventors: Jeffrey D. Rimer, Pankaj Karande
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Publication number: 20190144291Abstract: Embodiments of the invention generally provide compositions of crystalline zeolite materials with tailored crystal habits and the methods for forming such crystalline zeolite materials. The methods for forming the crystalline zeolite materials include binding one or more zeolite growth modifiers (ZGMs) to the surface of a zeolite crystal, which results in the modification of crystal growth rates along different crystallographic directions, leading to the formation of zeolites having a tailored crystal habit. The improved properties enabled by the tailored crystal habit include a minimized crystal thickness, a shortened internal diffusion pathlength, and a greater step density as compared to a zeolite having the native crystal habit prepared by traditional processes. The tailored crystal habit provides the crystalline zeolite materials with an aspect ratio of about 4 or greater and crystal surfaces having a step density of about 25 steps/?m2 or greater.Type: ApplicationFiled: November 8, 2018Publication date: May 16, 2019Applicant: University of Houston SystemInventors: Jeffrey D. Rimer, Manjesh Kumar
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Patent number: 10285961Abstract: In an embodiment of the present disclosure, there is provided a composition for dissolving calcium oxalate crystals thereby inhibiting/preventing further growth of crystals. In some embodiments, such a composition comprises at least one stereoisomer of hydroxycitrate, a derivative of the organic acid citrate. Such a method comprises administering to the subject an effective amount of the aforementioned composition. In another embodiment, the present disclosure pertains to a method of treating kidney stone disorder. Such a method comprises administering to a subject in need thereof a therapeutically effective amount of the aforementioned composition. In yet another embodiment, the present disclosure relates to a method of treating calcium oxalate stone disease. In an embodiment, the method comprises administering to a subject in need thereof a therapeutically effective amount of the aforementioned composition.Type: GrantFiled: April 27, 2015Date of Patent: May 14, 2019Assignee: University of Houston SystemInventors: Jeffrey D. Rimer, Jihae Chung, John Asplin
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Patent number: 10246489Abstract: In an embodiment, the present disclosure pertains to a composition for inhibiting calcium oxalate monohydrate crystal growth comprising at least one isolated polypeptide comprising a plurality of amino acids that bind the surface of the calcium oxalate monohydrate crystal; and a plurality of amino acids spacers, wherein the amino acid spacers are arranged in varying sequences between the plurality of amino acids that bind the surface of the calcium oxalate monohydrate crystal. In some embodiments, the present disclosure related to a method of controlling calcium oxalate monohydrate crystal growth in a subject in need thereof comprising administering to the subject therapeutically effective amount of the calcium oxalate monohydrate inhibiting polypeptide. In some embodiments, the present disclosure relates to a method of identifying calcium oxalate monohydrate inhibiting peptides.Type: GrantFiled: March 1, 2017Date of Patent: April 2, 2019Assignees: UNIVERSITY OF HOUSTON, RENSSELAER POLYTECHNIC INSTITUTEInventors: Jeffrey D. Rimer, Pankaj Karande
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Patent number: 10173903Abstract: Embodiments of the invention generally provide compositions of crystalline zeolite materials with tailored crystal habits and the methods for forming such crystalline zeolite materials. The methods for forming the crystalline zeolite materials include binding one or more zeolite growth modifiers (ZGMs) to the surface of a zeolite crystal, which results in the modification of crystal growth rates along different crystallographic directions, leading to the formation of zeolites having a tailored crystal habit. The improved properties enabled by the tailored crystal habit include a minimized crystal thickness, a shortened internal diffusion pathlength, and a greater step density as compared to a zeolite having the native crystal habit prepared by traditional processes. The tailored crystal habit provides the crystalline zeolite materials with an aspect ratio of about 4 or greater and crystal surfaces having a step density of about 25 steps/?m2 or greater.Type: GrantFiled: June 16, 2014Date of Patent: January 8, 2019Assignee: UNIVERSITY OF HOUSTON SYSTEMInventors: Jeffrey D. Rimer, Manjesh Kumar
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Publication number: 20170369327Abstract: Methods of controlling crystal polymorphism in organic-free synthesis of Na-Zeolites and the zeolite crystals formed using those methods are provided. The methods disclosed herein create certain types of zeolite crystals more efficiently than other previously known methods. The methods also create certain types of zeolite crystals in a form and concentration not previously disclosed. The methods disclosed herein generally comprise using solutions with varying ratios of silicon (Si), aluminum (Al), hydroxide (OH), and water. Some implementations of the invention disclosed include efficient methods of producing nearly pure cancrinite (CAN), methods of obtaining sodalite in solutions with a high Si/Al ratio, and a method of forming thin, platelet-like ANA crystals with a width of less than about 1 ?m and a length of at least about 3 ?m.Type: ApplicationFiled: June 21, 2017Publication date: December 28, 2017Inventors: Jeffrey D. RIMER, Miguel MALDONADO, Matthew D. OLEKSIAK
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Publication number: 20170283459Abstract: In an embodiment, the present disclosure pertains to a composition for inhibiting calcium oxalate monohydrate crystal growth comprising at least one isolated polypeptide comprising a plurality of amino acids that bind the surface of the calcium oxalate monohydrate crystal; and a plurality of amino acids spacers, wherein the amino acid spacers are arranged in varying sequences between the plurality of amino acids that bind the surface of the calcium oxalate monohydrate crystal. In some embodiments, the present disclosure related to a method of controlling calcium oxalate monohydrate crystal growth in a subject in need thereof comprising administering to the subject therapeutically effective amount of the calcium oxalate monohydrate inhibiting polypeptide. In some embodiments, the present disclosure relates to a method of identifying calcium oxalate monohydrate inhibiting peptides.Type: ApplicationFiled: March 1, 2017Publication date: October 5, 2017Inventors: Jeffrey D. Rimer, Pankaj Karande
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Publication number: 20170247261Abstract: In an embodiment, the present disclosure pertains to a composition comprising a zeolite with high silica content. In some embodiments, the silica to aluminum ratio (SAR) for the zeolite is 2:1. In some embodiments, the zeolite comprises Zeolite HOU-2 (LTA-type). In some embodiments, the silica to aluminum ratio (SAR) for the zeolite is >3. In some embodiments, the zeolite comprises Zeolite HOU-3 (FAU type). In some embodiments, the zeolite is synthesized using a one-step method. In some embodiments, the zeolite is synthesized without the use of an organic structure-directing agent (OSDA). In some embodiments, the zeolite is synthesized without the use of post-synthesis dealumination. In some embodiments, the zeolite is synthesized without the use crystal seeds. In some embodiments, the zeolite is used in commercial ion exchange. In some embodiments, the zeolite is used for catalysis reaction. In some embodiments, the zeolite is highly thermostable.Type: ApplicationFiled: September 17, 2015Publication date: August 31, 2017Applicant: University of Houston SystemInventors: Marlon T. Conato, Matthew D. Oleksiak, Jeffrey D. Rimer