Patents by Inventor Jeffrey D. Scholten

Jeffrey D. Scholten has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • COMPOSITIONS AND METHODS FOR INHIBITION OF TRIGLYCERIDE SYNTHESIS VIA SYNERGISTIC COMBINATION OF BOTANICAL FORMULATIONS
    Publication number: 20150258158
    Abstract: Compositions and methods for inhibition of triglyceride synthesis via synergistic combination of botanical extracts are described. Specifically, the present invention relates to treating or preventing weight gain or obesity, promoting weight loss, appetite suppression, or the like, as well as managing skin oil production through a synergistic inhibition of diacylglycerol acyltransferase-I (DGAT-I) enzyme involved in the triglyceride synthesis and modulation of sterol regulatory element binding protein Ic (SREBP-Ic) and/or peroxisome proliferator activated receptor gamma coactivator I-alpha (PGCI?).
    Type: Application
    Filed: February 26, 2015
    Publication date: September 17, 2015
    Applicant: Access Business Group International LLC
    Inventors: Rodney A. Velliquette, Russell Keith Randolph, Jeffrey D. Scholten, Arun Rajgopal, Kevin Gellenbeck, Chun Hu, Kerry Grann, Kristin Morris
  • Substituted dinaphthylmethyl and diheteroarylmethylacetyl histidine inhibitors of protein farnesyltransferase
    Patent number: 6008372
    Abstract: Substituted histidine compounds of formula (I) are described as well as methods for the preparation and pharamaceutical compositions of same, which are useful as inhibitors of protein famesyltransferase and for the treatment of proliferative diseases including cancer, restenosis, and psoriasis, and as antiviral agents.
    Type: Grant
    Filed: July 2, 1998
    Date of Patent: December 28, 1999
    Assignee: Warner-Lambert Company
    Inventors: Annette M. Doherty, James S. Kaltenbronn, Daniele Leonard, John Quin, III, Jeffrey D. Scholten
  • Tricyclic inhibitors of protein farnesyltransferase
    Patent number: 5919780
    Abstract: Compounds of formula I ##STR1## wherein X is N or C--R.sup.9, Y is N--R.sup.10, CH.sub.2, O, S, SO, SO.sub.2, C.dbd.O or CH--OH,R is H or alkyl,R.sup.1 is heteroaryl,n is 1-5, andR.sup.2 -R.sup.10 are H or various substituents,are useful as inhibitors of protein farnesyl transferase and for the treatment of proliferative diseases including cancer, restenosis and psoriasis, and as antiviral agents.
    Type: Grant
    Filed: December 11, 1997
    Date of Patent: July 6, 1999
    Assignee: Warner Lambert Company
    Inventors: Gary L. Bolton, Annette M Doherty, James S. Kaltenbronn, John Quin, III, Jeffrey D. Scholten, Judith Sebolt-Leopold, Harold Zinnes