Patents by Inventor Jeffrey Dennis Brodin

Jeffrey Dennis Brodin has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • METHODS AND COMPOSITIONS FOR IDENTIFYING LIGANDS ON ARRAYS USING INDEXES AND BARCODES
    Publication number: 20230313275
    Abstract: Some embodiments provided herein include methods and compositions for the detection of target ligands on an array. In some embodiments, a capture probe specifically binds to a target ligand from a sample, the location of a bead comprising the capture probe in an array is determined, and the bead is decoded to identify the capture probe and the sample. In some embodiments, a barcode is indicative of a capture probe attached to a bead; and an index is indicative of a subpopulation of beads. In some embodiments, the barcode and the index are determined by sequencing.
    Type: Application
    Filed: April 18, 2023
    Publication date: October 5, 2023
    Inventors: Darren Segale, Fiona E. Black, Jeffrey Dennis Brodin, Jeffrey Fisher, Lorenzo Berti, Siew Hong Leong
  • Methods and compositions for identifying ligands on arrays using indexes and barcodes
    Patent number: 11667957
    Abstract: Some embodiments provided herein include methods and compositions for the detection of target ligands on an array. In some embodiments, a capture probe specifically binds to a target ligand from a sample, the location of a bead comprising the capture probe in an array is determined, and the bead is decoded to identify the capture probe and the sample. In some embodiments, a barcode is indicative of a capture probe attached to a bead; and an index is indicative of a subpopulation of beads. In some embodiments, the barcode and the index are determined by sequencing.
    Type: Grant
    Filed: October 23, 2019
    Date of Patent: June 6, 2023
    Assignee: Illumina, Inc.
    Inventors: Darren Segale, Fiona E. Black, Jeffrey Dennis Brodin, Jeffrey Fisher, Lorenzo Berti, Siew Hong Leong
  • METHOD AND COMPOSITIONS FOR PREPARING NUCLEIC ACID LIBRARIES
    Publication number: 20230105642
    Abstract: Embodiments relate to the preparation of nucleic acid libraries. Some embodiments relate to the preparation of normalized nucleic acid libraries, such as libraries in which the amounts of amplified nucleic acids are substantially the same for different amounts of input nucleic acids. Some embodiments relate to preparation of indexed nucleic acid libraries with certain adaptors.
    Type: Application
    Filed: March 29, 2021
    Publication date: April 6, 2023
    Inventors: Lena Christiansen, Dmitry Pokholok, Frank J. Steemers, Rigo Pantoja, Megan Chu, Patrizia lavicoli, Weihua Chang, Jeffrey Dennis Brodin, Eric Vermaas, Jerishah Thomas, Fan Zhang
  • METHODS AND COMPOSITIONS FOR IDENTIFYING LIGANDS ON ARRAYS USING INDEXES AND BARCODES
    Publication number: 20210087613
    Abstract: Some embodiments provided herein include methods and compositions for the detection of target ligands on an array. In some embodiments, a capture probe specifically binds to a target ligand from a sample, the location of a bead comprising the capture probe in an array is determined, and the bead is decoded to identify the capture probe and the sample. In some embodiments, a barcode is indicative of a capture probe attached to a bead; and an index is indicative of a subpopulation of beads. Some embodiments relate to sequencing target polynucleotides from several different nucleic acids samples on a bead array.
    Type: Application
    Filed: September 18, 2020
    Publication date: March 25, 2021
    Inventors: Darren Segale, Fiona E. Black, Jeffrey Dennis Brodin, Lorenzo Berti, Siew Hong Leong, Jeffrey S. Fisher, Allen Eckhardt, Rui Zhang, Yin Nah Teo
  • METHODS AND COMPOSITIONS FOR IDENTIFYING LIGANDS ON ARRAYS USING INDEXES AND BARCODES
    Publication number: 20200131570
    Abstract: Some embodiments provided herein include methods and compositions for the detection of target ligands on an array. In some embodiments, a capture probe specifically binds to a target ligand from a sample, the location of a bead comprising the capture probe in an array is determined, and the bead is decoded to identify the capture probe and the sample. In some embodiments, a barcode is indicative of a capture probe attached to a bead; and an index is indicative of a subpopulation of beads. In some embodiments, the barcode and the index are determined by sequencing.
    Type: Application
    Filed: October 23, 2019
    Publication date: April 30, 2020
    Inventors: Lorenzo Berti, Fiona E. Black, Jeffrey Dennis Brodin, Jeffrey Fisher