Abstract: A protective layer for use on a sensor during a manufacturing process avoids damage to the sensor and keeps the sensor surface clean during lens fabrication. The protective layer includes a non-cross-linked, water-soluble polymer layer and an anhydrous, cross-linkable, methacrylate-based formulation layer, temporarily applied to a surface of the sensor. The protective layer may be used to protect the sensor during a manufacturing process by applying the non-cross-linked, water-soluble polymer layer and the anhydrous, cross-linkable, methacrylate-based formulation layer consecutively onto the surface of the sensor to form the protective layer; affixing the sensor to a substrate; fabricating a device that includes the substrate; and subsequently removing the protective layer from the surface of the sensor.

Abstract: Embodiments are disclosed of an eye-mountable device (EMD) including a lens enclosure including an anterior layer and a posterior layer sealed to the anterior layer. An anterior electrode is disposed within the lens enclosure on a concave side of the anterior layer, a posterior electrode is disposed within the lens enclosure on a convex side of the posterior layer, and an electrochromic element is disposed across a central region of the lens enclosure, wherein the electrochromic element separates the anterior electrode from the posterior electrode within the central region.

Abstract: An eye-mountable device includes a lens enclosure, an anterior conductive electrode, a posterior conductive electrode, and an accommodation actuator element. The lens enclosure includes an anterior layer and a posterior layer. The anterior conductive electrode is disposed within the lens enclosure and across a center region of the lens enclosure. The posterior conductive electrode is disposed within the lens enclosure and across the center region. The accommodation actuator element is disposed within the lens enclosure between the anterior and posterior conductive electrodes in the center region. The anterior and posterior conductive electrodes are transparent and electrically manipulate the accommodation actuator element.

Abstract: An eye-mountable device (EMD) includes a lens enclosure, liquid crystal material, first and second electrodes, a substrate, and a controller. The lens enclosure includes a first encapsulation layer and a second encapsulation layer sealed to the first encapsulation layer. The liquid crystal material is disposed across a central region of the lens enclosure. The first electrode is disposed within the lens enclosure between the first encapsulation layer and the liquid crystal material. The second electrode is disposed within the lens enclosure between the second encapsulation layer and the liquid crystal material. The substrate is disposed within the lens enclosure between the first and second encapsulation layers. The controller is disposed on the substrate and electrically coupled to the first and second electrodes to apply a voltage across the liquid crystal material.

Abstract: An eye-mountable device includes a lens enclosure, an anterior conductive electrode, a posterior conductive electrode, and an accommodation actuator element. The lens enclosure includes an anterior layer and a posterior layer. The anterior conductive electrode is disposed within the lens enclosure and across a center region of the lens enclosure. The posterior conductive electrode is disposed within the lens enclosure and across the center region. The accommodation actuator element is disposed within the lens enclosure between the anterior and posterior conductive electrodes in the center region. The anterior and posterior conductive electrodes are transparent and electrically manipulate the accommodation actuator element.

Abstract: An eye-mountable device includes a flexible lens enclosure, anterior and posterior flexible conductive electrodes, and an accommodation actuator element. The flexible lens enclosure includes anterior and posterior layers that are sealed together. The anterior flexible conductive electrode is disposed within the flexible enclosure and across a center region of the flexible lens enclosure on a concave side of the anterior layer. The posterior flexible conductive electrode is disposed within the flexible enclosure and across the center region on a convex side of the posterior layer. The accommodation actuator element is disposed between the first and second flexible conductive electrodes. The anterior and posterior flexible conductive electrodes are transparent and electrically manipulate the accommodation actuator element.

Abstract: An eye-mountable device (EMD) includes a lens enclosure, liquid crystal material, first and second electrodes, a substrate, and a controller. The lens enclosure includes a first encapsulation layer and a second encapsulation layer sealed to the first encapsulation layer. The liquid crystal material is disposed across a central region of the lens enclosure. The first electrode is disposed within the lens enclosure between the first encapsulation layer and the liquid crystal material. The second electrode is disposed within the lens enclosure between the second encapsulation layer and the liquid crystal material. The substrate is disposed within the lens enclosure between the first and second encapsulation layers. The controller is disposed on the substrate and electrically coupled to the first and second electrodes to apply a voltage across the liquid crystal material.

Abstract: Techniques and mechanisms for providing an eye-mountable device including an accommodation actuator. In an embodiment, fabrication of the eye-mountable device includes sealing layers of enclosure material to form a lens enclosure comprising a pinch-off region where the layers of enclosure material physically contact one another. The accommodation actuator includes a liquid crystal layer disposed between the layers of enclosure material in a central region around which the pinch-off region extends. In another embodiment, electrodes are disposed in the central region each between the liquid crystal layer and a respective one of the layers of enclosure material. The liquid crystal layer isolates the electrodes from one another in the central region.

Abstract: Embodiments are disclosed of an eye-mountable device (EMD) including a lens enclosure including an anterior layer and a posterior layer sealed to the anterior layer. An anterior electrode is disposed within the lens enclosure on a concave side of the anterior layer, a posterior electrode is disposed within the lens enclosure on a convex side of the posterior layer, and an electrochromic element is disposed across a central region of the lens enclosure, wherein the electrochromic element separates the anterior electrode from the posterior electrode within the central region.

Abstract: Biomedical devices such as contact lenses formed from a polymerization product of a mixture comprising (a) a multi-armed macromonomer comprising multiple side chains attached to a nucleus, wherein each side chain comprises a thio carbonyl thio fragment of the same or different reversible addition fragmentation chain transfer (“RAFT”) agent; and (b) one or more biomedical device-forming monomers are disclosed.

Abstract: An eye-mountable device includes a flexible lens enclosure, anterior and posterior flexible conductive electrodes, and an accommodation actuator element. The flexible lens enclosure includes anterior and posterior layers that are sealed together. The anterior flexible conductive electrode is disposed within the flexible enclosure and across a center region of the flexible lens enclosure on a concave side of the anterior layer. The posterior flexible conductive electrode is disposed within the flexible enclosure and across the center region on a convex side of the posterior layer. The accommodation actuator element is disposed between the first and second flexible conductive electrodes. The anterior and posterior flexible conductive electrodes are transparent and electrically manipulate the accommodation actuator element.

Abstract: Techniques and mechanisms for providing an eye-mountable device including an accommodation actuator. In an embodiment, fabrication of the eye-mountable device includes sealing layers of enclosure material to form a lens enclosure comprising a pinch-off region where the layers of enclosure material physically contact one another. The accommodation actuator includes a liquid crystal layer disposed between the layers of enclosure material in a central region around which the pinch-off region extends. In another embodiment, electrodes are disposed in the central region each between the liquid crystal layer and a respective one of the layers of enclosure material. The liquid crystal layer isolates the electrodes from one another in the central region.

Abstract: A method for modifying the refractive index of an optical, hydrogel polymeric material. The method comprises irradiating predetermined regions of an optical, polymeric material with a laser to form refractive structures. To facilitate the formation of the refractive structures the optical, hydrogel polymeric material comprises a photosensitizer. The presence of the photosensitizer permits one to set a scan rate to a value that is at least fifty times greater than a scan rate without the photosensitizer in the material, yet provides similar refractive structures in terms of the observed change in refractive index. Alternatively, the photosensitizer in the polymeric material permits one to set an average laser power to a value that is at least two times less than an average laser power without the photosensitizer in the material, yet provide similar refractive structures.

Abstract: A method involving forming a sacrificial layer on a working substrate; forming a first bio-compatible layer on the sacrificial layer such that the first bio-compatible layer adheres to the sacrificial layer, wherein the first bio-compatible layer defines a first side of a bio-compatible device; forming a conductive pattern on the first bio-compatible layer, the conductive pattern comprising a metal; mounting an electronic component to the conductive pattern; forming a self-assembled monolayer (SAM) on the conductive pattern by contacting the conductive pattern with a functionalized sulfur compound or a functionalized selenium compound; forming an adhesion layer on the SAM by contacting the SAM with an adhesion promoter; forming a second bio-compatible layer over the first bio-compatible layer, the electronic component, and the conductive pattern having the adhesion layer, wherein the second bio-compatible layer defines a second side of the bio-compatible device; and removing the sacrificial layer to release t

Abstract: A method for modifying the refractive index of an optical, hydrogel polymeric material. The method comprises irradiating predetermined regions of an optical, polymeric material with a laser to form refractive structures. To facilitate the formation of the refractive structures the optical, hydrogel polymeric material comprises a photosensitizer. The presence of the photosensitizer permits one to set a scan rate to a value that is at least fifty times greater than a scan rate without the photosensitizer in the material, yet provides similar refractive structures in terms of the observed change in refractive index. Alternatively, the photosensitizer in the polymeric material permits one to set an average laser power to a value that is at least two times less than an average laser power without the photosensitizer in the material, yet provide similar refractive structures.

Abstract: The present invention relates to polymeric compositions useful in the manufacture of biocompatible medical devices. More particularly, the present invention relates to certain monoethylenically unsaturated polymerizable group containing polycarbosiloxane monomers capable of polymerization to form polymeric compositions having desirable physical characteristics useful in the manufacture of ophthalmic devices.

Abstract: A method for modifying the refractive index of an optical, hydrogel polymeric material. The method comprises irradiating predetermined regions of an optical, polymeric material with a laser to form refractive structures. To facilitate the formation of the refractive structures the optical, hydrogel polymeric material comprises a photosensitizer. The presence of the photosensitizer permits one to set a scan rate to a value that is at least fifty times greater than a scan rate without the photosensitizer in the material, yet provides similar refractive structures in terms of the observed change in refractive index. Alternatively, the photosensitizer in the polymeric material permits one to set an average laser power to a value that is at least two times less than an average laser power without the photosensitizer in the material, yet provide similar refractive structures.

Abstract: The present invention relates to polymeric compositions useful in the manufacture of biocompatible medical devices. More particularly, the present invention relates to certain monoethylenically unsaturated polymerizable group containing polycarbosiloxane monomers capable of polymerization to form polymeric compositions having desirable physical characteristics useful in the manufacture of ophthalmic devices.

Abstract: This invention describes the use of polymerizable surfactants as comonomers in forming ophthalmic devices such as contact lenses, intraocular lenses, corneal implants, etc.

Abstract: Biomedical devices such as silicone hydrogels formed from a polymerization product of a mixture comprising (a) a siloxane-containing homopolymer which has only one thio carbonyl thio fragment of a reversible addition fragmentation chain transfer (RAFT) agent; and (b) one or more biomedical device-forming comonomers are disclosed.