Patents by Inventor Jeffrey Gildersleeve

Jeffrey Gildersleeve has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • Biomarkers for prostate cancer and methods for their detection
    Patent number: 9804163
    Abstract: The invention provides a method for predicting the clinical response to a cancer vaccine in a patient having cancer, a method for determining the immune response to a cancer vaccine in a patient having cancer who has been administered a cancer vaccine, a method for determining the long-term survival in a patient having cancer, corresponding kits therefor, as well as methods of for improving the efficacy of a virus-based vaccine.
    Type: Grant
    Filed: August 5, 2011
    Date of Patent: October 31, 2017
    Assignee: The United States of America, as represented by the Secretary, Department of Health and Human Services
    Inventors: Jeffrey Gildersleeve, Christopher Campbell, Oyindasola Oyelaran, James Gulley, Jeffrey Schlom
  • BIOMARKERS FOR PROSTATE CANCER AND METHODS FOR THEIR DETECTION
    Publication number: 20170052185
    Abstract: The invention provides a method for predicting the clinical response to a cancer vaccine in a patient having cancer, a method for determining the immune response to a cancer vaccine in a patient having cancer who has been administered a cancer vaccine, a method for determining the long-term survival in a patient having cancer, corresponding kits therefor, as well as methods of for improving the efficacy of a virus-based vaccine.
    Type: Application
    Filed: November 8, 2016
    Publication date: February 23, 2017
    Applicant: The United States of America, as represented by the Secretary, Department of Health and Human Serv
    Inventors: Jeffrey Gildersleeve, Christopher Campbell, Oyindasola Oyelaran, James Gulley, Jeffrey Schlom
  • Antibodies that bind GalNAc1-3Gal, pharmaceutical compositions and methods of using same
    Patent number: 8957188
    Abstract: Monoclonal antibodies to carbohydrate antigens containing a terminal GalNAc?1-3Gal are provided. The antibodies of the present invention are found to specifically recognize GalNAc?1-3Gal with little cross-reactivity to other structurally similar antigens such as GalNAc?1-6Gal, blood group A, Forssman antigen and the Tn antigen on both solution assays and human tissue. Compositions comprising the monoclonal antibodies, as well as methods of diagnosis, treatment and prognostication are also provided.
    Type: Grant
    Filed: April 1, 2010
    Date of Patent: February 17, 2015
    Assignee: The United States of America, as represented by the Secretary, Department of Health and Human Services
    Inventors: Jeffrey Gildersleeve, Zhitao Li, Qian Li, Miriam Anver, Donna O. Butcher
  • BIOMARKERS FOR PROSTATE CANCER AND METHODS FOR THEIR DETECTION
    Publication number: 20130156813
    Abstract: The invention provides a method for predicting the clinical response to a cancer vaccine in a patient having cancer, a method for determining the immune response to a cancer vaccine in a patient having cancer who has been administered a cancer vaccine, a method for determining the long-term survival in a patient having cancer, corresponding kits therefor, as well as methods of for improving the efficacy of a virus-based vaccine.
    Type: Application
    Filed: August 5, 2011
    Publication date: June 20, 2013
    Inventors: Jeffrey Gildersleeve, Christopher Campbell, Oyindasola Oyelaran, James Gulley, Jeffrey Schlom
  • ANTIBODIES THAT BIND GalNAc1-3Gal, PHARMACEUTICAL COMPOSITIONS AND METHODS OF USING SAME
    Publication number: 20100254898
    Abstract: Monoclonal antibodies to carbohydrate antigens containing a terminal GalNAc?1-3Gal are provided. The antibodies of the present invention are found to specifically recognize GalNAc?1-3Gal with little cross-reactivity to other structurally similar antigens such as GalNAc?1-6Gal, blood group A, Forssman antigen and the Tn antigen on both solution assays and human tissue. Compositions comprising the monoclonal antibodies, as well as methods of diagnosis, treatment and prognostication are also provided.
    Type: Application
    Filed: April 1, 2010
    Publication date: October 7, 2010
    Applicants: Human Services
    Inventors: Jeffrey Gildersleeve, Zhitao Li, Qian Li, Miriam Anver, Donna O. Butcher