Abstract: This application relates to substituted benzimidazoles, compositions comprising them and their uses in the treatment of diseases and conditions in which inhibition of a bromodomain is indicated. For example, the application relates to substituted benzimidazoles and to their use as bromodomain inhibitors. The present application is also related to the treatment or prevention of proliferative disorders, auto-immune disorders, inflammatory disorders, dermal disorders, and neoplasms, including tumors and/or cancers.

Abstract: A method for gesture-based multi-factor authentication includes mapping a gesture password to a first substitution string, generating a cryptographic key using the first substitution string as an input to a password authenticated key exchange protocol, encrypting a challenge response with the cryptographic key to generate an encrypted challenge response, and transmitting, to a relying party computing system, a first authentication message comprising the encrypted challenge response and a user identifier identifying a user.

Abstract: The disclosed embodiments include systems and methods to provide a patient suffering from at least one communication and memory impairment with positive stimuli. In one of such embodiments, the method includes obtaining data indicative of a current condition of a first patient. The method also includes determining, based on prior patient data of the first patient, a first stimulus that triggered a positive response from the first patient while the first patient was in a condition similar to the current condition. The method further includes providing a first recommendation for the first patient to experience the first stimulus for display on an electronic device. The method further includes receiving a first response triggered by the first stimulus. The method further includes storing data indicative of the first response in a storage medium.

Abstract: A device and method facilitates communication with a network-based service or application such as a Social Networking Service (SNS), for example. The device may be a cellular telephone that is not normally equipped to communicate with such services. However, a controller in the device selects a bearer service that can be used to communicate with the service.

Abstract: A device and method facilitates communication with a network-based service or application such as a Social Networking Service (SNS), for example. The device may be a cellular telephone that is not normally equipped to communicate with such services. However, a controller in the device selects a bearer service that can be used to communicate with the service.

Abstract: Reclosable bags having a slider-actuated string zipper and tamper-evident features. In one aspect, the bag comprises: a receptacle having a mouth and an interior volume; a string zipper installed in the mouth; a slider mounted to the string zipper; a membrane depending within the interior volume to block access to a portion of the interior volume when the string zipper is open; and a hood joined to the receptacle and shrouding the mouth. The membrane is made by forming a gusset. Then a string zipper is installed inside of the gusset and heat sealed in place. Later a hood or shroud is attached to the bag walls at an elevation traversed by the gusset panels. A layer of non-sealable material is applied on a surface of a gusset panel to prevent the gusset panels from being sealed together when the hood is heat sealed to the bag walls.

Abstract: A reclosable plastic bag (38) having a fin seal (35) which provides a weakness area (23, 80, 81, 84, 86) that extends into at least one side of the fin seal (35). Perforation axes (19, 20) for opening the reclosable plastic bag (38) may be aligned with the weakness area (23, 80, 81, 84, 86). A method of making the bag is also disclosed.

Abstract: A mobile terminal includes a processor operatively associated with a radio communications circuit and configured to store a podcast including an embedded link to content outside of the mobile terminal. The processor is further configured to control activation of the embedded link responsive to a communications status of the mobile terminal and/or a configuration of a user interface of the mobile terminal. For example, the communications status may include availability of communications between the mobile terminal and a storage location of the content, or presence of a particular call and/or a message. The user interface configuration may include, for example, a current display mode or physical arrangement of the terminal.

Abstract: The system of the invention includes the provision of a bookmark associated with the content file such that the bookmark will save the place in the content file where play back of the content was stopped. The bookmark may be based on a content consumed data comprising total or percentage of elapsed time or data consumed or other measure of consumed data. In one embodiment the bookmark is contained in a separate bookmark file that is created in the user device and associated with the content file. In an alternate embodiment a wrapper is provided as part of the content file where the wrapper includes the bookmark information.

Abstract: A wireless communications device that sends and receives presence status information is configured to detect when it is proximate a predefined zone. A receiver in the wireless communications device receives presence information from a transmitter associated with the predefined zone. The presence information defines a new presence status for the wireless communications device, and may include an indicator associated with the new presence status. Upon receipt of the presence information, a controller in the wireless communications device automatically changes the current presence status of the wireless communications device to the new presence status, and publishes the changed status to a remote entity. If the new presence status is not defined in memory, the controller may add the new presence status to memory.

Abstract: A low-cost infra-red detector is disclosed including a method of making and using the same. The detector employs a substrate, a filtering layer, a converting layer, and a diverter to be responsive to wavelengths up to about 1600 nm. The detector is useful for a variety of applications including spectroscopy, imaging, and defect detection.

Abstract: A method of making a reclosable plastic bag (38) having a fin seal (35) which provides a weakness area (23, 80, 81, 84, 86) that extends into at least one side of the fin seal (35). Perforation axes (19, 20) for opening the reclosable plastic bag (38) may be aligned with the weakness area (23, 80, 81, 84, 86). A reclosable bag (38) made in accordance with the method is also disclosed.

Abstract: A method of making a reclosable plastic bag (38) having a fin seal (35) which provides a weakness area (23, 80, 81, 84, 86) that extends into at least one side of the fin seal (35). Perforation axes (19, 20) for opening the reclosable plastic bag (38) may be aligned with the weakness area (23, 80, 81, 84, 86). A reclosable bag (38) made in accordance with the method is also disclosed.

Abstract: Reclosable bags having a slider-actuated string zipper and tamper-evident features. In one aspect, the bag comprises: a receptacle having a mouth and an interior volume; a string zipper installed in the mouth; a slider mounted to the string zipper; a membrane depending within the interior volume to block access to a portion of the interior volume when the string zipper is open; and a hood joined to the receptacle and shrouding the mouth. The membrane is made by forming a gusset. Then a string zipper is installed inside of the gusset and heat sealed in place. Later a hood or shroud is attached to the bag walls at an elevation traversed by the gusset panels. A layer of non-sealable material is applied on a surface of a gusset panel to prevent the gusset panels from being sealed together when the hood is heat sealed to the bag walls.

Abstract: A method of making a reclosable plastic bag (38) having a fin seal (35) which provides a weakness area (23, 80, 81, 84, 86) that extends into at least one side of the fin seal (35). Perforation axes (19, 20) for opening the reclosable plastic bag (38) may be aligned with the weakness area (23, 80, 81, 84, 86). A reclosable bag (38) made in accordance with the method is also disclosed.

Abstract: A quick-on cap (10) is provided for engaging a filler neck (22). The cap (10) includes a closure for closing the mouth of the filler neck (22) and a gripping mechanism for gripping the filler neck (22) to establish a fuel vapor seal between the closure and the filler neck (22). The closure includes a core (18) and a sleeve (14) that is movable relative to the core (18). The sleeve (14) carries a sealing ring (34) that is configured to seal against the filler neck (22). The gripping mechanism is coupled to the core (18) and sleeve (14) and grips the filler neck (22) to compress the sealing ring (34) between the sleeve (14) and the filler neck (22) in response to movement of the core (18) relative to the sleeve (14) in a cap-installation direction. The closure also includes a handle cover (12) coupled to the core (18) to make it easy for a user to move the core (18) relative to the sleeve (14) in the cap-installation direction an amount sufficient to actuate the gripping mechanism.

Abstract: A filler neck includes an internal tube that is movable to open and close the filler neck. The movable tube is formed to include a fill passageway that extends therethrough and is configured to deliver fuel from a fuel-dispensing nozzle to a vehicle fuel tank when the filler neck is open. The "moving" fill passageway is closed when the filler neck is closed and opened when the filler neck is opened. An inlet opening into the moving fill passageway is formed in an outer end of the movable tube and an outlet opening for discharging liquid fuel from the moving fill passageway for delivery to the fuel tank is formed in an inner end of the movable tube. A fill passageway closure member is appended to a filler neck conduit and positioned to lie in a filler neck vent passageway in spaced-apart relation to the mouth of the conduit.

Abstract: A layered label for containers and the like. The label has for the outermost layer, a thin scratchable surface that when scratched, reveals a contrasting color below. By scratching through the surface of the label, one may legibly write information on the label. The label allows consumers to conveniently record information on an article with a fingernail and therefore without the need for a writing implement. The label may be a single layer of scratchable coating over a contrasting color on the surface of the container, or it may be three layers, in which the scratchable coating is the top layer applied over a base label of contrasting color with pressure sensitive adhesive and a peel away backing on the bottom layer.

Abstract: An assembly is provided for controlling filling of a vehicle fuel tank having a filler neck. The assembly includes a capless fuel and fuel vapor handling system for controlling a filling operation of a fuel tank and the discharge of fuel vapors from the tank and filler neck both during and after the filling operation.

Abstract: A device and method facilitates communication with a network-based service or application such as a Social Networking Service (SNS), for example. The device may be a cellular telephone that is not normally equipped to communicate with such services. However, a controller in the device selects a bearer service that can be used to communicate with the service.