Patents by Inventor Jeffrey H. Siewerdsen

Jeffrey H. Siewerdsen has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • Publication number: 20190311505
    Abstract: Selected artifacts, which may be based on distortions or selected attenuation features, may be reduced or removed from a reconstructed image. Various artifacts may occur due to the presence of a metal object in a field of view. The metal object may be identified and removed from a data that is used to generate a reconstruction.
    Type: Application
    Filed: April 4, 2019
    Publication date: October 10, 2019
    Inventors: Patrick A. Helm, Jeffrey H. Siewerdsen, Ali Uneri, Wojciech Zbijewski, Xiaoxuan Zhang, Joseph W. Stayman, IV
  • Patent number: 10426554
    Abstract: A tracking and navigation system is provided. The system includes an imaging or treatment device, a tracker device, and a fiducial marker. At least part of the imaging or treatment device is movable relative to a patient. The tracker device is mounted on the imaging or treatment device and is movable therewith relative to the patient. The fiducial marker may be fixed relative to the patient to define a patient coordinate system. The fiducial marker is detectable by the tracker device to substantially maintain registration between the tracker device and the patient coordinate system. A tracking and navigation kit including the tracker device and at least one fiducial marker may also be provided, for example, for retrofitting to existing imaging or treatment devices.
    Type: Grant
    Filed: April 30, 2012
    Date of Patent: October 1, 2019
    Assignee: The Johns Hopkins University
    Inventors: Jeffrey H. Siewerdsen, Yoshito Otake, Russell H. Taylor
  • Patent number: 10405812
    Abstract: An apparatus for cone beam computed tomography can include a support structure, a scanner assembly coupled to the support structure for controlled movement in at least x, y and z orientations, the scanner assembly can include a DR detector configured to move along at least a portion of a detector path that extends at least partially around a scan volume with a distance D1 that is sufficiently long to allow the scan volume to be positioned within the detector path; a radiation source configured to move along at least a portion of a source path outside the detector path, the source path having a distance D2 greater than the distance D1, the distance D2 being sufficiently long to allow adequate radiation exposure of the scan volume for an image capture by the detector; and a first gap in the detector path.
    Type: Grant
    Filed: August 21, 2017
    Date of Patent: September 10, 2019
    Assignees: Carestream Health, Inc., The Johns Hopkins University
    Inventors: Michael A. Litzenberger, Peter A. Newman, John Yorkston, Andrew J. Hartmann, Jeffrey H. Siewerdsen, Douglas M. Csaszar
  • Patent number: 10368956
    Abstract: An embodiment in accordance with the present invention provides a technique for localizing structures of interest in projection images (e.g., x-ray projection radiographs or fluoroscopy) based on structures defined in a preoperative 3D image (e.g., MR or CT). Applications include, but are not limited to, spinal interventions. The present invention achieves 3D-2D image registration (and particularly allowing use with a preoperative MR image) by segmenting the structures of interest in the preoperative 3D image and generating a simulated projection of the segmented structures to be aligned with the 2D projection image. Other applications include various clinical scenarios involving 3D-2D image registration, such as image-guided cranial neurosurgery, orthopedic surgery, biopsy, and radiation therapy.
    Type: Grant
    Filed: February 16, 2017
    Date of Patent: August 6, 2019
    Assignee: The Johns Hopkins University
    Inventors: Jeffrey H. Siewerdsen, Wathudurage Tharindu De Silva, Ali Uneri, Michael Ketcha, Sureerat Reaungamornrat, Jean-Paul Wolinsky
  • Patent number: 10307115
    Abstract: A system for cone beam computed tomography of an extremity has an x-ray source and a digital radiographic detector both revolved about a central imaging axis so that the detector moves at least partially around a first extremity of a patient and, if the extremity is the leg of the patient, the detector moves between the legs of the patient. The detector path has a radial distance less than that of the source path. A housing that encloses the source and detector includes a pivoting door to allow sideways access for the patient's leg to be placed at the central imaging axis.
    Type: Grant
    Filed: June 14, 2018
    Date of Patent: June 4, 2019
    Assignee: Carestream Health, Inc.
    Inventors: John Yorkston, Robert J. Asento, Jeffrey H. Siewerdsen, David H. Foos
  • Patent number: 10262424
    Abstract: An embodiment in accordance with the present invention provides a method for 3D-2D registration (for example, registration of a 3D CT image to a 2D radiograph) that permits deformable motion between structures defined in the 3D image based on a series of locally rigid transformations. This invention utilizes predefined annotations in 3D images (e.g., the location of anatomical features of interest) to perform multiple locally rigid registrations that yield improved accuracy in aligning structures that have undergone deformation between the acquisition of the 3D and 2D images (e.g., a preoperative CT compared to an intraoperative radiograph). The 3D image is divided into subregions that are masked according to the annotations, and the registration is computed simultaneously for each divided region by incorporating a volumetric masking method within the 3D-2D registration process.
    Type: Grant
    Filed: December 16, 2016
    Date of Patent: April 16, 2019
    Assignee: The Johns Hopkins University
    Inventors: Michael Ketcha, Wathudurage Tharindu deSilva, Ali Uneri, Jean-Paul Wolinsky, Jeffrey H. Siewerdsen
  • Publication number: 20180296172
    Abstract: A system for cone beam computed tomography of an extremity has an x-ray source and a digital radiographic detector both revolved about a central imaging axis so that the detector moves at least partially around a first extremity of a patient and, if the extremity is the leg of the patient, the detector moves between the legs of the patient. The detector path has a radial distance less than that of the source path. A housing that encloses the source and detector includes a pivoting door to allow sideways access for the patient's leg to be placed at the central imaging axis.
    Type: Application
    Filed: June 14, 2018
    Publication date: October 18, 2018
    Inventors: John YORKSTON, Robert J. ASENTO, Jeffrey H. SIEWERDSEN, David H. FOOS
  • Patent number: 10064591
    Abstract: A novel method for simulating radiation dose reduction that enables previews of low-dose x-ray projection images, low-dose computed tomography images and/or cone-beam CT images. Given an existing projection or set of projections of the patient acquired at a nominal dose, the method provides a means to produce highly accurate preview images that accurately reflect the image quality associated with reduced radiation dose. The low-dose preview image accounts for characteristics of the imaging system, including blur, variations in detector gain and electronic noise, and does so in a manner that yields accurate depiction of the magnitude and correlation of image noise in the preview images. A calibration step may be included to establish the system-specific relationship between the mean and variance in detector signal, and incorporate an accurate model for system blur such that correlations in the resulting LDP images are accurate.
    Type: Grant
    Filed: July 9, 2015
    Date of Patent: September 4, 2018
    Assignee: The Johns Hopkins University
    Inventors: Adam Wang, Jeffrey H. Siewerdsen
  • Patent number: 10010295
    Abstract: An apparatus for cone beam computed tomography of an extremity has a digital radiation detector and a first device to move the detector along a circular detector path extending so that the detector moves both at least partially around a first extremity of the patient and between the first extremity and a second, adjacent extremity. The detector path has radius R1 sufficient to position the extremity approximately centered in the detector path. There is a radiation source with a second device to move the source along a concentric circular source path having a radius R2 greater than radius R1, radius R2 sufficiently long to allow adequate radiation exposure of the first extremity for an image capture by the detector. A first circumferential gap in the source path allows the second extremity to be positioned in the first circumferential gap during image capture.
    Type: Grant
    Filed: February 6, 2017
    Date of Patent: July 3, 2018
    Inventors: John Yorkston, Robert J. Asento, Jeffrey H. Siewerdsen, David H. Foos
  • Patent number: 9936924
    Abstract: An embodiment in accordance with the present invention provides a method for applying task-based performance predictors (measures of noise, spatial resolution, and detectability index) based on numerical observer models and approximations to the local noise and spatial resolution properties of the CBCT reconstruction process (e.g., penalized-likelihood iterative reconstruction). These predictions are then used to identify projections views (i.e., points that will constitute the scan trajectory) that maximize task performance, beginning with the projection view that maximizes detectability, proceeding to the next-best view, and continuing in an (arbitrarily constrained) orbit that can be physically realized on advanced robotic C-arm platforms.
    Type: Grant
    Filed: March 26, 2014
    Date of Patent: April 10, 2018
    Assignee: The Johns Hopkins University
    Inventors: Joseph Webster Stayman, Jeffrey H. Siewerdsen
  • Patent number: 9907516
    Abstract: An apparatus for cone beam computed tomography can include a support structure, a scanner assembly coupled to the support structure for controlled movement in at least x, y and z orientations, the scanner assembly can include a DR detector configured to move along at least a portion of a detector path that extends at least partially around a scan volume with a distance D1 that is sufficiently long to allow the scan volume to be positioned within the detector path; a radiation source configured to move along at least a portion of a source path outside the detector path, the source path having a distance D2 greater than the distance D1, the distance D2 being sufficiently long to allow adequate radiation exposure of the scan volume for an image capture by the detector; and a first gap in the detector path.
    Type: Grant
    Filed: October 7, 2013
    Date of Patent: March 6, 2018
    Assignees: Carestream Health, Inc., The Johns Hopkins University
    Inventors: Michael A. Litzenberger, Peter A. Newman, John Yorkston, Andrew J. Hartmann, Jeffrey H. Siewerdsen, Douglas M. Csaszar
  • Publication number: 20180028127
    Abstract: An apparatus for cone beam computed tomography can include a support structure, a scanner assembly coupled to the support structure for controlled movement in at least x, y and z orientations, the scanner assembly can include a DR detector configured to move along at least a portion of a detector path that extends at least partially around a scan volume with a distance D1 that is sufficiently long to allow the scan volume to be positioned within the detector path; a radiation source configured to move along at least a portion of a source path outside the detector path, the source path having a distance D2 greater than the distance D1, the distance D2 being sufficiently long to allow adequate radiation exposure of the scan volume for an image capture by the detector; and a first gap in the detector path.
    Type: Application
    Filed: August 21, 2017
    Publication date: February 1, 2018
    Inventors: Michael A. Litzenberger, Peter A. Newman, John Yorkston, Andrew J. Hartmann, Jeffrey H. Siewerdsen, Douglas M. Csaszar
  • Patent number: 9826953
    Abstract: An embodiment in accordance with the present invention provides a device and method for a quantitatively calibrated computed tomography scanner. The device includes a gantry configured for receiving a patient or part of a patient. The gantry includes an X-ray source and a detector positioned opposite said X-ray source, such that said detector receives the X-rays emitted from the X-ray source. Calibration phantoms are integrated with the gantry and/or a device within the scanner so as to allow for calibration in quantitative CT measurements of Hounsfield units and/or bone mineral density.
    Type: Grant
    Filed: June 7, 2013
    Date of Patent: November 28, 2017
    Assignee: THE JOHNS HOPKINS UNIVERSITY
    Inventors: Jeffrey H. Siewerdsen, Abdullah Al Muhit, John Carrino
  • Patent number: 9770214
    Abstract: An apparatus for cone beam computed tomography of an extremity has a digital radiation detector and a first device to move the detector along a circular detector path extending so that the detector moves both at least partially around a first extremity of the patient and between the first extremity and a second, adjacent extremity. The detector path has radius R1 sufficient to position the extremity approximately centered in the detector path. There is a radiation source with a second device to move the source along a concentric circular source path having a radius R2 greater than radius R1, radius R2 sufficiently long to allow adequate radiation exposure of the first extremity for an image capture by the detector. A first circumferential gap in the source path allows the second extremity to be positioned in the first circumferential gap during image capture.
    Type: Grant
    Filed: February 7, 2017
    Date of Patent: September 26, 2017
    Inventors: John Yorkston, Robert J. Asento, Jeffrey H. Siewerdsen, David H. Foos
  • Publication number: 20170238897
    Abstract: The present invention is directed to a method for enabling volumetric image reconstruction from unknown projection geometry of tomographic imaging systems, including CT, cone-beam CT (CBCT), and tomosynthesis systems. The invention enables image reconstruction in cases where it was not previously possible (e.g., custom-designed trajectories on robotic C-arms, or systems using uncalibrated geometries), and more broadly offers improved image quality (e.g., improved spatial resolution and reduced streak artifact) and robustness to patient motion (e.g., inherent compensation for rigid motion) in a manner that does not alter the patient setup or imaging workflow. The method provides a means for accurately estimating the complete geometric description of each projection acquired during a scan by simulating various poses of the x-ray source and detector to determine their unique, scan-specific positions relative to the patient, which is often unknown or inexactly known (e.g.
    Type: Application
    Filed: February 17, 2017
    Publication date: August 24, 2017
    Inventors: Jeffrey H. Siewerdsen, Yoshito Otake, Joseph Webster Stayman, Ali Uneri, Adam S. Wang, Sarah Ouadah
  • Publication number: 20170231713
    Abstract: An embodiment in accordance with the present invention provides a technique for localizing structures of interest in projection images (e.g., x-ray projection radiographs or fluoroscopy) based on structures defined in a preoperative 3D image (e.g., MR or CT). Applications include, but are not limited to, spinal interventions. The present invention achieves 3D-2D image registration (and particularly allowing use with a preoperative MR image) by segmenting the structures of interest in the preoperative 3D image and generating a simulated projection of the segmented structures to be aligned with the 2D projection image. Other applications include various clinical scenarios involving 3D-2D image registration, such as image-guided cranial neurosurgery, orthopedic surgery, biopsy, and radiation therapy.
    Type: Application
    Filed: February 16, 2017
    Publication date: August 17, 2017
    Inventors: Jeffrey H. Siewerdsen, Wathudurage Tharindu De Silva, Ali Uneri, Michael Ketcha, Sureerat Reaungamornrat, Jean-Paul Wolinsky
  • Publication number: 20170178349
    Abstract: An embodiment in accordance with the present invention provides a method for 3D-2D registration (for example, registration of a 3D CT image to a 2D radiograph) that permits deformable motion between structures defined in the 3D image based on a series of locally rigid transformations. This invention utilizes predefined annotations in 3D images (e.g., the location of anatomical features of interest) to perform multiple locally rigid registrations that yield improved accuracy in aligning structures that have undergone deformation between the acquisition of the 3D and 2D images (e.g., a preoperative CT compared to an intraoperative radiograph). The 3D image is divided into subregions that are masked according to the annotations, and the registration is computed simultaneously for each divided region by incorporating a volumetric masking method within the 3D-2D registration process.
    Type: Application
    Filed: December 16, 2016
    Publication date: June 22, 2017
    Inventors: Michael Ketcha, Wathudrage Tharindu deSilva, Ali Uneri, Jean-Paul Wolinsky, Jeffrey H. Siewerdsen
  • Publication number: 20170156683
    Abstract: An apparatus for cone beam computed tomography of an extremity has a digital radiation detector and a first device to move the detector along a circular detector path extending so that the detector moves both at least partially around a first extremity of the patient and between the first extremity and a second, adjacent extremity. The detector path has radius R1 sufficient to position the extremity approximately centered in the detector path. There is a radiation source with a second device to move the source along a concentric circular source path having a radius R2 greater than radius R1, radius R2 sufficiently long to allow adequate radiation exposure of the first extremity for an image capture by the detector. A first circumferential gap in the source path allows the second extremity to be positioned in the first circumferential gap during image capture.
    Type: Application
    Filed: February 7, 2017
    Publication date: June 8, 2017
    Inventors: John Yorkston, Robert J. Asento, Jeffrey H. Siewerdsen, David H. Foos
  • Publication number: 20170143285
    Abstract: An apparatus for cone beam computed tomography of an extremity has a digital radiation detector and a first device to move the detector along a circular detector path extending so that the detector moves both at least partially around a first extremity of the patient and between the first extremity and a second, adjacent extremity. The detector path has radius R1 sufficient to position the extremity approximately centered in the detector path. There is a radiation source with a second device to move the source along a concentric circular source path having a radius R2 greater than radius R1, radius R2 sufficiently long to allow adequate radiation exposure of the first extremity for an image capture by the detector. A first circumferential gap in the source path allows the second extremity to be positioned in the first circumferential gap during image capture.
    Type: Application
    Filed: February 6, 2017
    Publication date: May 25, 2017
    Inventors: John Yorkston, Robert J. Asento, Jeffrey H. Siewerdsen, David H. Foos
  • Publication number: 20170135659
    Abstract: A novel method for simulating radiation dose reduction that enables previews of low-dose x-ray projection images, low-dose computed tomography images and/or cone-beam CT images. Given an existing projection or set of projections of the patient acquired at a nominal dose, the method provides a means to produce highly accurate preview images that accurately reflect the image quality associated with reduced radiation dose. The low-dose preview image accounts for characteristics of the imaging system, including blur, variations in detector gain and electronic noise, and does so in a manner that yields accurate depiction of the magnitude and correlation of image noise in the preview images. A calibration step may be included to establish the system-specific relationship between the mean and variance in detector signal, and incorporate an accurate model for system blur such that correlations in the resulting LDP images are accurate.
    Type: Application
    Filed: July 9, 2015
    Publication date: May 18, 2017
    Applicant: The Johns Hopkins University
    Inventors: Adam Wang, Jeffrey H. Siewerdsen