Patents by Inventor Jeffrey I. Stein

Jeffrey I. Stein has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • Patent number: 5824542
    Abstract: The present invention provides a dual method for producing male-sterile plants. Two genetically transformed plants, parents 1 and 2 are crossed to obtain male-sterile offspring. Parent 1 is transformed with an expression cassette comprising a nucleotide sequence encoding an anther-specific promoter which is operably linked to a nucleotide sequence encoding a transactivator. Parent 2 is transformed with an expression cassette comprising a target nucleotide sequence, which is capable of being activated by the transactivator, operably linked to a nucleotide sequence which encodes RNA or a polypeptide which will disrupt the formation of viable pollen. Therefore, crossing parent 1 with parent 2 results in male-sterile offspring. The male-sterile plants are useful for producing hybrid seed.The invention also provides compositions and methods for high level expression of a coding region of interest in a plant.
    Type: Grant
    Filed: May 23, 1995
    Date of Patent: October 20, 1998
    Assignee: Novartis Finance Corporation
    Inventors: Lyle D. Crossland, Annmarie Tuttle, Jeffrey I. Stein
  • Patent number: 5710031
    Abstract: Gene activating sequences which activate the expression of other bacterial genes, which are latent or expressed at low levels, are provided. The gene activating sequences confer the ability to produce several metabolites and may be transferred to bacterial strains. The transformed biocontrol agents are active to inhibit the growth of the fungal pathogens.
    Type: Grant
    Filed: June 2, 1995
    Date of Patent: January 20, 1998
    Assignee: Novartis Finance Corporation
    Inventors: Thomas D. Gaffney, Stephen T. Lam, James M. Ligon, Dwight Steven Hill, Jeffrey I. Stein
  • Patent number: 5670350
    Abstract: Gene activating sequences which activate the expression of other bacterial genes, which are latent or expressed at low levels, are provided. The gene activating sequences confer the ability to produce several metabolites and may be transferred to bacterial strains. The transformed biocontrol agents are active to inhibit the growth of the fungal pathogens.
    Type: Grant
    Filed: August 8, 1994
    Date of Patent: September 23, 1997
    Assignee: Novartis Finance Corporation
    Inventors: Thomas D. Gaffney, Stephen T. Lam, Dwight Steven Hill, Jeffrey I. Stein, James M. Ligon
  • Patent number: 5659124
    Abstract: The present invention provides a dual method for producing male-sterile plants. Two genetically transformed plants, parents 1 and 2 are crossed to obtain male-sterile offspring. Parent 1 is transformed with an expression cassette comprising a nucleotide sequence encoding an anther-specific promoter which is operably linked to a nucleotide sequence encoding a transactivator. Parent 2 is transformed with an expression cassette comprising a target nucleotide sequence, which is capable of being activated by the transactivator, operably linked to a nucleotide sequence which encodes RNA or a polypeptide which will disrupt the formation of viable pollen. Therefore, crossing parent 1 with parent 2 results in male-sterile offspring. The male-sterile plants are useful for producing hybrid seed.The invention also provides compositions and methods for high level expression of a coding region of interest in a plant.
    Type: Grant
    Filed: January 3, 1995
    Date of Patent: August 19, 1997
    Assignee: Novartis Corporation
    Inventors: Lyle D. Crossland, Annmarie Tuttle, Jeffrey I. Stein
  • Patent number: 5409823
    Abstract: The present invention provides a dual method for producing male-sterile plants. Two genetically transformed plants, parents 1 and 2 are crossed to obtain male-sterile offspring. Parent 1 is transformed with an expression cassette comprising a nucleotide sequence encoding an anther-specific promoter which is operably linked to a nucleotide sequence encoding a transactivator. Parent 2 is transformed with an expression cassette comprising a target nucleotide sequence, which is capable of being activated by the transactivator, operably linked to a nucleotide sequence which encodes RNA or a polypeptide which will disrupt the formation of viable pollen. Therefore, crossing parent 1 with parent 2 results in male-sterile offspring. The male-sterile plants are useful for producing hybrid seed.The invention also provides compositions and methods for high level expression of a coding region of interest in a plant.
    Type: Grant
    Filed: September 24, 1992
    Date of Patent: April 25, 1995
    Assignee: Ciba-Geigy Corporation
    Inventors: Lyle D. Crossland, Annmarie Tuttle, Jeffrey I. Stein
  • Patent number: 4521915
    Abstract: A scanning radio receiver intended for use on the frequencies assigned to the Public Safety Radio Services and which is also operable for reception in the aircraft band from 118 MHz to 136 MHz. A ROM contains data establishing frequency limits and other information such that frequencies assigned to a number of service categories can be automatically searched in response to operation of service keys of a keyboard with the information storage requirements being minimized. For a service band having single frequencies or groups of frequencies which are not separated by fixed frequency increments, the data identifies the number of such frequencies or groups, the number of frequencies in each and a limit frequency of each. A processor outputs a frequency code to a frequency synthesizer while also processing input and stored data to develop the next code to be output.
    Type: Grant
    Filed: May 28, 1980
    Date of Patent: June 4, 1985
    Assignee: Masco Corporation of Indiana
    Inventors: William Baker, Gordon H. Smith, Xio I. Beach, Gary F. Sallee, Jeffrey I. Stein