Patents by Inventor Jeffrey Ian Boucher

Jeffrey Ian Boucher has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • CAS ENDONUCLEASES AND RELATED METHODS
    Publication number: 20250092426
    Abstract: Provided herein are Cas endonucleases (and functional fragments, functional variants, and domains thereof), nucleic acid molecules encoding the same, and systems comprising the same. The disclosure further relates to methods of utilizing the Cas endonucleases (or nucleic acid molecules encoding the same), including, e.g., in methods of editing a nucleic acid molecule (e.g., a gene) and methods of treating diseases (e.g., genetic diseases).
    Type: Application
    Filed: July 24, 2024
    Publication date: March 20, 2025
    Inventors: Molly Krisann GIBSON, Pengfei TIAN, Iain James MCFADYEN, Athanasios Dimitri DOUSIS, Jeffrey Ian BOUCHER, Panagiota KYRIAKOU, Pradeep RAMESH
  • CAS ENDONUCLEASES AND RELATED METHODS
    Publication number: 20250092375
    Abstract: Provided herein are Cas endonucleases (and functional fragments, functional variants, and domains thereof), nucleic acid molecules encoding the same, and systems comprising the same. The disclosure further relates to methods of utilizing the Cas endonucleases (or nucleic acid molecules encoding the same), including, e.g., in methods of editing a nucleic acid molecule (e.g., a gene) and methods of treating diseases (e.g., genetic diseases).
    Type: Application
    Filed: July 24, 2024
    Publication date: March 20, 2025
    Inventors: Molly Krisann GIBSON, Pengfei TIAN, Iain James MCFADYEN, Athanasios Dimitri DOUSIS, Jeffrey Ian BOUCHER, Panagiota KYRIAKOU, Pradeep RAMESH
  • Biosynthesis of mogrosides
    Patent number: 12234464
    Abstract: Provided herein are enzymes (e.g., cucurbitadienol synthases (CDS), UDP-glycosyltransferases (UGT), C11 hydroxylases, epoxide hydrolases (EPH), squalene epoxidases, and/or cytochrome P450 reductases), host cells expressing the enzymes, and methods of producing mogrol precursors, mogrol, and/or mogrosides using such host cells.
    Type: Grant
    Filed: November 9, 2019
    Date of Patent: February 25, 2025
    Assignee: Ginkgo Bioworks, Inc.
    Inventors: Jeffrey Ian Boucher, Nicholas Flores, Jaide Jensen, Dayal Saran, Jue Wang
  • ENGINEERED SESQUITERPENE SYNTHASES
    Publication number: 20250027070
    Abstract: Provided in this disclosure are engineered sesquiterpene synthases, host cells expressing engineered sesquiterpene synthases and methods for making alpha-guaiene.
    Type: Application
    Filed: November 18, 2022
    Publication date: January 23, 2025
    Applicant: Ginkgo Bioworks, Inc.
    Inventors: Jeffrey Ian Boucher, Dylan Alexander Carlin, Cinzia Formighieri, Bryan Greenhagen, Jaide Jensen, Scott Marr
  • PRODUCTION OF VACCINIA CAPPING ENZYME
    Publication number: 20240182877
    Abstract: Aspects of the disclosure relate to production of vaccinia capping enzyme (VCE) in host cells. For example, host cells may comprise: a promoter; a ribosome binding site (RBS); a nucleic acid encoding a vaccinia capping enzyme (VCE) or VCE subunit; and a terminator.
    Type: Application
    Filed: March 29, 2022
    Publication date: June 6, 2024
    Applicant: Ginkgo Bioworks, Inc.
    Inventors: Josef Bober, Jeffrey Ian Boucher, Justin Michael Gardin, Jason King, Scott Marr, Matthew McMahon, Krishnaben S. Patel, Abraham Waldman
  • BIOSYNTHESIS OF CANNABINOIDS AND CANNABINOID PRECURSORS
    Publication number: 20240026392
    Abstract: Aspects of the disclosure relate to biosynthesis of cannabinoids and cannabinoid precursors in recombinant cells and in vitro, and to variant terminal synthases having altered catalytic activity to synthesize THC-type, CBD-type and/or CBC-type cannabinoids.
    Type: Application
    Filed: July 8, 2021
    Publication date: January 25, 2024
    Applicant: Ginkgo Bioworks, Inc.
    Inventors: Kim Cecelia Anderson, Jeffrey Ian Boucher, Elena Brevnova, Brian Carvalho, Nicholas Flores, Katrina Forrest, Fiona Qu, Gabriel Rodrigues, Michelle Spencer
  • BIOSYNTHESIS OF MOGROSIDES
    Publication number: 20230174993
    Abstract: Described in this application are UDP-glycosyltransferases (UGT) enzymes, host cells expressing the UGTs, and methods of producing mogrol precursors, mogrol, and/or mogrosides using such host cells.
    Type: Application
    Filed: May 13, 2021
    Publication date: June 8, 2023
    Applicant: Ginkgo Bioworks, Inc.
    Inventors: Jeffrey Ian Boucher, Justin Michael Gardin, Scott Marr, Matthew McMahon, Krishnaben S. Patel, Jie Zhu
  • BIOSYNTHESIS OF MOGROSIDES
    Publication number: 20220378072
    Abstract: The disclosure relates to enzymes, such as cucurbitadienol synthase (CDS), UDP-glycosyltransferase (UGT), C11 hydroxylase, epoxide hydrolase (EPH), squalene epoxidase (SQE), and/or cytochrome P450 reductase enzymes, recombinant host cells expressing the enzymes, and methods of producing mogrol precursors, mogrol, and/or mogrosides using such recombinant cells.
    Type: Application
    Filed: October 23, 2020
    Publication date: December 1, 2022
    Applicant: Ginkgo Bioworks, Inc.
    Inventors: Jeffrey Ian Boucher, Matthew McMahon, Scott Marr, Jie Zhu
  • Protective enzymes
    Patent number: 11359182
    Abstract: The present invention relates to methods and compositions that include enzymes and/or binding polypeptides useful for protecting polymers from damage caused by fatty acids from secreted biological fluids such as sebum or sweat.
    Type: Grant
    Filed: September 12, 2018
    Date of Patent: June 14, 2022
    Assignee: Ginkgo Bioworks, Inc.
    Inventors: Patrick Magannig Boyle, Jeffrey Ian Boucher, Michael Gregory Napolitano
  • BIOSYNTHESIS OF MOGROSIDES
    Publication number: 20210403921
    Abstract: Described in this application are enzymes (e.g., cucurbitadienol synthases (CDS), UDP-glycosyltransferases (UGT), C11 hydroxylases, epoxide hydrolases (EPH), squalene epoxidases, and/or cytochrome P450 reductases), host cells expressing the enzymes, and methods of producing mogrol precursors, mogrol, and/or mogrosides using such host cells.
    Type: Application
    Filed: November 9, 2019
    Publication date: December 30, 2021
    Applicant: Ginkgo Bioworks, Inc.
    Inventors: Kim Cecelia Anderson, Jeffrey Ian Boucher, Nicholas Flores, Jaide Jensen, Scott Marr, Matthew McMahon, Dayal Saran, Jue Wang, Jie Zhu
  • PROTECTIVE ENZYMES
    Publication number: 20200255809
    Abstract: The present invention relates to methods and compositions that include enzymes and/or binding polypeptides useful for protecting polymers from damage caused by fatty acids from secreted biological fluids such as sebum or sweat.
    Type: Application
    Filed: September 12, 2018
    Publication date: August 13, 2020
    Applicant: Ginkgo Bioworks, Inc.
    Inventors: Patrick Magannig Boyle, Jeffrey Ian Boucher, Michael Gregory Napolitano