Patents by Inventor Jeffrey J. Blumenstein

Jeffrey J. Blumenstein has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • 2,3-epoxy alcohols, acids and derivatives as anti retroviral chemotherapeutic agents
    Patent number: 6153589
    Abstract: The present invention is related to compounds, compositions and methods of treating viral infections. Compounds of the present invention have the following general formula: ##STR1## wherein R is selected from --CH.sub.2 OH, --CO.sub.2 R.sup.2, --CONR.sup.3 R.sup.4, or COR.sup.5, wherein R.sup.2 is hydrogen or a lower alkyl group, R.sup.3 and R.sup.4 are each independently hydrogen or a lower alkyl group, R.sup.5 is an amino acid residue bound via a terminal nitrogen or peptide having at least two amino acid residues; and wherein R.sup.1 is C.sub.5 -C.sub.13 alkyl, aryl, aralkyl, aralkyl(lower alkyl)ether, or C.sub.5 -C.sub.13 alkyl(lower alkyl)ether.
    Type: Grant
    Filed: December 15, 1992
    Date of Patent: November 28, 2000
    Assignee: The United States of America as represented by the Department of Health and Human Services
    Inventors: Jeffrey J. Blumenstein, Christopher J. Michejda, Stephen Oroszlan, Terry Copeland
  • Bistriazenes as chemotherapeutic agents
    Patent number: 5808038
    Abstract: The present invention is directed to bistriazene compounds, pharmaceutical compositions containing effective anti-cancer amounts of these compounds, a method for treating cancer comprising administering to affected subjects an anti-cancer effective amount of a bistriazene compound, and the use of bistriazene compounds as crosslinking reagents applicable to the synthesis and manipulation of polymeric macromolecules.
    Type: Grant
    Filed: September 12, 1994
    Date of Patent: September 15, 1998
    Assignee: The United States of America as represented by the Secretary of the Department of Health and Human Services
    Inventors: Christopher J. Michejda, Jeffrey J. Blumenstein
  • Bistriazenes as chemotherapeutic agents
    Patent number: 5731301
    Abstract: The present invention is directed to bistriazene compounds, pharmaceutical compositions containing effective anti-cancer amounts of these compounds, a method for treating cancer comprising administering to affected subjects an anti-cancer effective amount of a bistriazene compound, and the use of bistriazene compounds as crosslinking reagents applicable to the synthesis and manipulation of polymeric macromolecules.
    Type: Grant
    Filed: May 31, 1995
    Date of Patent: March 24, 1998
    Assignee: The United States of America as represented by the Department of Health and Human Services
    Inventors: Christopher J. Michejda, Jeffrey J. Blumenstein
  • Bistriazenes as chemotherapeutic agents
    Patent number: 5672593
    Abstract: The present invention is directed to bistriazene compounds, pharmaceutical compositions containing effective anti-cancer amounts of these compounds, a method for treating cancer comprising administering to affected subjects an anti-cancer effective amount of a bistriazene compound, and the use of bistriazene compounds as crosslinking reagents applicable to the synthesis and manipulation of polymeric macromolecules.
    Type: Grant
    Filed: June 28, 1993
    Date of Patent: September 30, 1997
    Assignee: The United States of America as represented by the Department of Health and Human Services
    Inventors: Christopher J. Michejda, Jeffrey J. Blumenstein
  • 2,3-epoxy derivatives as anti retrovital chemotherapeutic agents
    Patent number: 5190969
    Abstract: The present invention is related to compounds, compositions and methods of treating viral infections. Compounds of the present invention have the following general formula: ##STR1## wherein R is selected from --CH.sub.2 OH, --CO.sub.2 R.sup.2, --CONR.sup.3 R.sup.4, or COR.sup.5, wherein R.sup.2 is hydrogen or a lower alkyl group, R.sup.3 and R.sup.4 are each independently hydrogen or a lower alkyl group, R.sup.5 is an amino acid residue bound via a terminal nitrogen or peptide having at least two amino acid residues; and wherein R.sup.1 is C.sub.5 -C.sub.13 alkyl, aryl, aralkyl, aralkyl(lower alkyl) ether, or C.sub.5 -C.sub.13 alkyl (lower alkyl)ether.
    Type: Grant
    Filed: December 20, 1988
    Date of Patent: March 2, 1993
    Assignee: The United States of America as represented by the Secretary of the Department of Health & Human Services
    Inventors: Jeffrey J. Blumenstein, Christopher J. Michejda, Stephen Oroszlan, Terry Copeland