Abstract: Embodiments provided herein relate to methods and compositions for next generation sequencing. Some embodiments include the preparation of a template library from a target nucleic acid using one-sided transposition, sequencing the template library, and capturing the contiguity information.

Abstract: An example of a flow cell includes a substrate and a reaction area defined in or over the substrate. The reaction area includes two angularly offset and non-perpendicular surfaces relative to a planar surface of the substrate, a polymeric hydrogel positioned over at least a portion of each of the two angularly offset and non-perpendicular surfaces; a first primer set attached to the polymeric hydrogel that is positioned over the portion of a first of the two angularly offset and non-perpendicular surfaces; and a second primer set attached to the polymeric hydrogel that is positioned over the portion of a second of the two angularly offset and non-perpendicular surfaces, wherein the first and second primer sets are orthogonal.

Abstract: An oral treatment composition that includes a carrier, an active agent and a silicon dioxide compound. The active agent can be a variety of compositions, such as dental whitening or bleaching agents, desensitizing agents, antimicrobials, anti-plaque agents, remineralizing agents, anti-tartar agents, mouth fresheners, and anesthetics. Optionally, a processing aid can be added to the composition to streamline manufacture of the gel. The composition can be formed as a bead in a dental tray so that when a user applies the dental tray to their dental arch, the bead readily spreads over the surfaces of the teeth without the user having to supply significant force to achieve such spreading.

Abstract: A dental flosser including a plastic handle having proximal and distal ends, a flosser head at the distal end of the handle, and two spaced apart arms extending from the flosser head. First and second strands of dental floss extend transversely between the spaced apart arms. The first and second strands may different material characteristics from each other, such as different coefficients of friction. The first and second strands may be arranged on the arms to provide enhanced cleaning. For instance, a portion of one of the strands may be offset from the other strand along the width of the flosser arms.

Abstract: An oral care composition including a hydrophilic, aliphatic, polyether-based thermoplastic polyurethane, a glycol polymer, and a poly(N-vinyl lactam). These components form a tacky film having a thickness of about 1 mils to about 50 mils. A whitening agent, such as a peroxide, can be absorbed into the tacky film, and adapted to desorb from the tacky film to whiten teeth to which the film is joined. A method is also provided in which the components are extruded through a twin screw extruder and output to a die to produce the film. The whitening agent can be deposited on the film and absorbed by the film to form a relatively stable oral care composition including the whitening agent.

Abstract: An orally administered composition for relieving or eliminating snoring is described. The composition generally has four mechanisms of action for combating snoring. The composition includes a tissue-firming or astringent agent to firm up throat tissue. The composition also includes a soothing agent to soothe irritated or inflamed tissues. Also included in the composition is a lubricant to moisten dry or dehydrated tissues, and a mucous-thinning or expectorant agent to help remove any obstructive matter near the throat tissues.

Abstract: An oral treatment composition that includes a carrier, an active agent and a silicon dioxide compound. The active agent can be a variety of compositions, such as dental whitening or bleaching agents, desensitizing agents, antimicrobials, anti-plaque agents, remineralizing agents, anti-tartar agents, mouth fresheners, and anesthetics. Optionally, a processing aid can be added to the composition to streamline manufacture of the gel. The composition can be formed as a bead in a dental tray so that when a user applies the dental tray to their dental arch, the bead readily spreads over the surfaces of the teeth without the user having to supply significant force to achieve such spreading.

Abstract: An oral care strip includes a substrate having a first side and a second side. An oral care substance is disposed on the first side and a flavor element is attached to the second side. The flavor element may be a dissolvable, edible, flavored film. A method for forming the oral care strip includes the steps of a) applying an oral care substance to a first side of a substrate and b) attaching a flavor element to a second side of the substrate. The second side of the substrate may include a wax layer to which the flavor element is attached.

Abstract: An oral care composition including a hydrophilic, aliphatic, polyether-based thermoplastic polyurethane, a glycol polymer, and a poly(N-vinyl lactam). These components form a tacky film having a thickness of about 1 mils to about 50 mils. A whitening agent, such as a peroxide, can be absorbed into the tacky film, and adapted to desorb from the tacky film to whiten teeth to which the film is joined. A method is also provided in which the components are extruded through a twin screw extruder and output to a die to produce the film. The whitening agent can be deposited on the film and absorbed by the film to form a relatively stable oral care composition including the whitening agent.

Abstract: An orally administered composition for relieving or eliminating snoring is described. The composition generally has four mechanisms of action for combating snoring. The composition includes a tissue-firming or astringent agent to firm up throat tissue. The composition also includes a soothing agent to soothe irritated or inflamed tissues. Also included in the composition is a lubricant to moisten dry or dehydrated tissues, and a mucous-thinning or expectorant agent to help remove any obstructive matter near the throat tissues.

Abstract: A container for receiving and holding emesis has an inclined body providing an inclined chamber for storing emesis. A curved funnel has a small end joined to the body and a large inclined end surrounding an inclined mouth. A handle is joined to the funnel adjacent the lower portion of the large inclined end. A cover is snapped on the large inclined end of the funnel to contain emesis and odor within the container.

Abstract: Concentrated all-purpose liquid cleaning compositions are prepared that contain high levels of surfactants and solvents and exhibit improved cleaning performance and homogeneity in solution. A preferred formulation incorporates an actives system of a three component mixture: an anionic surfactant such as alkyl ethoxy sulfates, alkyl ethoxy carboxylates and mixtures thereof, a nonionic surfactant such as fatty alcohol ethoxylates, nonylphenol ethoxylates, alkylpolyglycosides and mixtures thereof, a glycol ether solvent and the balance comprising water and optional ingredients to provide a concentrated cleaning composition which can be diluted by the end user to the desired strength. Another preferred embodiment discloses a method of using a concentrated liquid cleaning composition.

Abstract: An improved scenting system having a frangible vial containing scented liquid disposed within a flexible, moisture-proof sheath member and a wick member having a first end disposed adjacent to the frangible vial and a second end extending from the sheath member, wherein the frangible vial may be broken and the scented liquid released for evaporation by the wick member without the hunter coming into contact with the scented liquid and wherein the scented liquid does not experience unwanted evaporation prior to use.

Abstract: A method for cleaning a hard surface with concentrated all-purpose liquid cleaning compositions that contain high levels of surfactants and solvents and which exhibit improved cleaning performance and homogeneity in solution. A preferred formulation incorporates an actives systems of a three component mixture: an anionic surfactant such as alkyl ethoxy sulfates, alkyl ethoxy carboxylates and mixtures thereof, a nonionic surfactant such as fatty alcohol ethoxylates, nonylphenol ethoxylates, alkylpolyglycosides and mixtures thereof, a glycol ether solvent and optional ingredients to provide a concentrated cleaning composition which can be diluted to the desired strength.