Abstract: A stackable case assembly includes a case bottom and a case together defining a cavity to receive at least a roll support including a shaft and at least one spacer coupled to an end portion or an opposite end portion of the shaft. The case top includes a second peripheral edge configured to mate with a first peripheral edge of the case bottom. In a transportation configuration, the case top is releasably joined with the case bottom using one or more latches. In a storage configuration, one of the case top or case bottom is configured to nest within the other. A system for storing or transporting a roll of product includes a pallet, a plurality of stackable case assemblies stacked one on top of the other and on the pallet, and one or more cleats disposed on the pallet to secure the plural stackable case assemblies on the pallet.

Abstract: The present disclosure is directed to compounds and methods for the treatment of disorders associated with fluid retention or salt overload, such as heart failure (in particular, congestive heart failure), chronic kidney disease, end-stage renal disease, liver disease, and peroxisome proliferator-activated receptor (PPAR) gamma agonist-induced fluid retention. The present disclosure is also directed to compounds and methods for the treatment of hypertension. The present disclosure is also directed to compounds and methods for the treatment of gastrointestinal tract disorders, including the treatment or reduction of pain associated with gastrointestinal tract disorders.

Abstract: The present disclosure is directed to compounds and methods for the treatment of disorders associated with fluid retention or salt overload, such as heart failure (in particular, congestive heart failure), chronic kidney disease, end-stage renal disease, liver disease, and peroxisome proliferator-activated receptor (PPAR) gamma agonist-induced fluid retention. The present disclosure is also directed to compounds and methods for the treatment of hypertension. The present disclosure is also directed to compounds and methods for the treatment of gastrointestinal tract disorders, including the treatment or reduction of pain associated with gastrointestinal tract disorders.

Abstract: The present disclosure is directed to compounds and methods for the treatment of disorders associated with fluid retention or salt overload, such as heart failure (in particular, congestive heart failure), chronic kidney disease, end-stage renal disease, liver disease, and peroxisome proliferator-activated receptor (PPAR) gamma agonist-induced fluid retention. The present disclosure is also directed to compounds and methods for the treatment of hypertension. The present disclosure is also directed to compounds and methods for the treatment of gastrointestinal tract disorders, including the treatment or reduction of pain associated with gastrointestinal tract disorders.

Abstract: The present disclosure is directed to compounds and methods for the treatment of disorders associated with fluid retention or salt overload, such as heart failure (in particular, congestive heart failure), chronic kidney disease, end-stage renal disease, liver disease, and peroxisome proliferator-activated receptor (PPAR) gamma agonist-induced fluid retention. The present disclosure is also directed to compounds and methods for the treatment of hypertension. The present disclosure is also directed to compounds and methods for the treatment of gastrointestinal tract disorders, including the treatment or reduction of pain associated with gastrointestinal tract disorders.

Abstract: N-[1-oxo-(optionally 2-aza)-2-alkyl-3-(carboxyl or thiol or hydroxyaminocarbonyl or N-hydroxyformamido)-propyl]-(aryl or heteroaryl)-azacyclo4-7alkanes or thiazacyclo4-7alkanes, salts or prodrugs thereof have interesting properties, e.g., in the treatment or prevention of disorders amenable to treatment by PDF inhibitors, such as treatment of bacterial infections.

Abstract: N-[1-oxo-(optionally 2-aza)-2-alkyl-3-(carboxyl or thiol or hydroxyaminocarbonyl or N-hydroxyformamido)-propyl]-(aryl or heteroaryl)-azacyclo4-7alkanes or thiazacyclo4-7alkanes, salts or prodrugs thereof have interesting properties, e.g., in the treatment or prevention of disorders amenable to treatment by PDF inhibitors, such as treatment of bacterial infections.

Abstract: A system and method which provides simultaneous display of characters on one or more display monitors in multiple languages. The languages can include icon based languages such as Chinese and Japanese or can be traditional character based languages such as romance and Germanic languages. The system includes a main unit having a first memory in which the first memory includes character data stored in a plurality of languages. A portion of the character data in a first language corresponds to another portion of the character data in a second language, the portion of the character data in the first language and the portion of the character data in the second language are stored in the first memory at memory locations having an offset value from each other.

Abstract: N-[1-oxo-2-alkyl-3-(N-hydroxyformamido)-propyl]-(carbonylamino-aryl or -heteroaryl)-azacyclo4-7alkanes or thiazacyclo4-7alkanes or imidazacyclo4-7alkanes have interesting properties, e.g., in the treatment or prevention of disorders amenable to treatment by peptidyl deformylase inhibitors such as treatment of bacterial infections.

Abstract: N-[1-oxo-(optionally 2-aza)-2-alkyl-3-(carboxyl or thiol or hydroxyaminocarbonyl or N-hydroxyformamido)-propyl]-(aryl or heteroaryl)-azacyclo4-7alkanes or thiazacyclo4-7alkanes, salts or prodrugs thereof have interesting properties, e.g., in the treatment or prevention of disorders amenable to treatment by PDF inhibitors, such as treatment of bacterial infections.

Abstract: The present invention provides compounds and libraries of compounds having formula (I): wherein L, n, S and A are defined generally and subsets herein. These compounds and libraries of compounds are useful generally in the drug discovery process.

Abstract: N-[1-oxo-(optionally 2-aza)-2-alkyl-3-(carboxyl or thiol or hydroxyaminocarbonyl or N-hydroxyformamido)-propyl]-(aryl or heteroaryl)-azacyclo4-7alkanes or thiazacyclo4-7alkanes, salts or prodrugs thereof have interesting properties, e.g., in the treatment or prevention of disorders amenable to treatment by PDF inhibitors, such as treatment of bacterial infections.

Abstract: A system and method which provides simultaneous display of characters on one or more display monitors in multiple languages. The languages can include icon based languages such as Chinese and Japanese or can be traditional character based languages such as romance and Germanic languages. The system includes a main unit having a first memory in which the first memory includes character data stored in a plurality of languages. A portion of the character data in a first language corresponds to another portion of the character data in a second language, the portion of the character data in the first language and the portion of the character data in the second language are stored in the first memory at memory locations having an offset value from each other.

Abstract: A method and apparatus is disclosed to improve the metal yield by adjusting the tilt angle of a tilting vessel having a submerged tap hole. The tilt angle is adjusted in response to parameters inherent in the pouring process, i.e. the proximity of the vessel contents to the vessel lip, the age of the tap hole, the liquid head over the tap hole, etc. Additionally, methods are disclosed to enhance the metal yield by advancing or moving back the furnace without knowledge of the tilt angle. Moreover, such methods and apparatus can be implemented through the use of computer based algorithms. The methods can also be used to archive pouring parameter information for future uses such as training and reviewing.

Abstract: N-[1-oxo-(optionally 2-aza)-2-alkyl-3-(carboxyl or thiol or hydroxyaminocarbonyl or N-hydroxyformamido)-propyl]-(aryl or heteroaryl)-azacyclo4-7alkanes or thiazacyclo4-7alkanes, salts or prodrugs thereof have interesting properties, e.g., in the treatment or prevention of disorders amenable to treatment by PDF inhibitors, such as treatment of bacterial infections.

Abstract: N-[1-oxo-2-alkyl-3-(N-hydroxyformamido)-propyl]-(carbonylamino-aryl or -heteroaryl)-azacyclo4-7alkanes or thiazacyclo4-7alkanes or imidazacyclo4-7alkanes have interesting properties, e.g., in the treatment or prevention of disorders amenable to treatment by peptidyl deformylase inhibitors such as treatment of bacterial infections.

Abstract: A method and apparatus is disclosed to improve the metal yield by adjusting the tilt angle of a tilting vessel having a submerged tap hole. The tilt angle is adjusted in response to parameters inherent in the pouring process, i.e. the proximity of the vessel contents to the vessel lip, the age of the tap hole, the liquid head over the tap hole, etc. Additionally, methods are disclosed to enhance the metal yield by advancing or moving back the furnace without knowledge of the tilt angle. Moreover, such methods and apparatus can be implemented through the use of computer based algorithms. The methods can also be used to archive pouring parameter information for future uses such as training and reviewing.

Abstract: A method and apparatus for improving the yield of molten metal discharged from a metal production vessel limits the slag carryover by reducing turbulence of metal pouring through a discharge opening by inhibiting a vortex over the discharge opening, automatically sensing the presence of slag in the discharge opening, and terminating discharge through the opening in response to the detection of changing content through the discharged opening passage. Preferably, the inhibiting function includes inserting a slag reduction device, preferably a refractory body and maintaining the position of the device over the discharge nozzle. Preferably, the sensor is an electromagnetic coil that determines the change in content of the flow through the opening passage without direct contact with the contents of the opening. The combination of the slag vortex inhibitor and the flow content sensor is substantially improved metal pouring yield as demonstrated by actual slag reduction results.