Patents by Inventor Jeffrey Jeddaloh

Jeffrey Jeddaloh has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • DIRECT OLIGONUCLEOTIDE SYNTHESIS ON CELLS AND BIOMOLECULES
    Publication number: 20210198661
    Abstract: The invention is directed to methods for synthesizing oligonucleotides direction on biomolecules or cells living or fixed. In some embodiments, template-free enzymatic synthesis is implemented under biological conditions with successive cycles of (i) enzymatic addition of a 3?-O-blocked nucleoside triphosphate and (ii) enzymatic deblocking of the incorporated nucleotide to regenerate a free 3? hydroxyl. The invention has applications in single-cell cDNA library construction and analysis.
    Type: Application
    Filed: March 4, 2021
    Publication date: July 1, 2021
    Applicant: DNA Script SAS
    Inventors: Xavier Godron, Adrian Horgan, Sylvain Gariel, Jeffrey Jeddaloh, Robert Nicol, Thomas Ybert
  • DIRECT OLIGONUCLEOTIDE SYNTHESIS ON CELLS AND BIOMOLECULES
    Publication number: 20210009994
    Abstract: The invention is directed to methods for synthesizing oligonucleotides direction on biomolecules or cells living or fixed. In some embodiments, template-free enzymatic synthesis is implemented under biological conditions with successive cycles of (i) enzymatic addition of a 3?-O-blocked nucleoside triphosphate and (ii) enzymatic deblocking of the incorporated nucleotide to regenerate a free 3? hydroxyl. The invention has applications in single-cell cDNA library construction and analysis.
    Type: Application
    Filed: December 10, 2019
    Publication date: January 14, 2021
    Applicant: DNA Script SAS
    Inventors: Xavier Godron, Adrian Horgan, Sylvain Gariel, Jeffrey Jeddaloh, Robert Nicol, Thomas Ybert