Patents by Inventor Jeffrey L. Dalsin

Jeffrey L. Dalsin has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • Mono-layer thin film adhesive compounds and methods of synthesis and use
    Patent number: 10238767
    Abstract: The invention relates provides synthetic medical adhesives which exploit plant derivatives to form covalent bonds with amines and thiols on tissue surfaces.
    Type: Grant
    Filed: July 25, 2013
    Date of Patent: March 26, 2019
    Assignee: DSM IP ASSETS, B.V.
    Inventors: John L. Murphy, Jeffrey L. Dalsin, Arinne N. Lyman, Laura L. Bremer, Joel L. Broussard, Neil Winterbottom, Justin T. Koepsel
  • BIOADHESIVE COMPOUNDS AND METHODS OF SYNTHESIS AND USE
    Publication number: 20170266353
    Abstract: Synthesis methods for creating polymeric compounds comprising phenyl derivatives (PD), or PDp i.e., polymers modified with PD, with desired surface active effects are described. The polymer backbone of PDp has structural or performance features that can be tailored to control physical properties of PDp, allowing it to be useful for different applications i.e., tissue adhesives or sealants, adhesion promoting coatings, and antifouling coatings.
    Type: Application
    Filed: May 13, 2015
    Publication date: September 21, 2017
    Inventors: John L MURPHY, Christopher P RADANO, Jeffrey L. DALSIN, Justin T. KOEPSEL
  • ADHESIVE COMPOUNDS AND METHODS USE FOR HERNIA REPAIR
    Publication number: 20160346424
    Abstract: The invention describes new synthetic medical adhesives and films which exploit the key components of natural marine mussel adhesive proteins.
    Type: Application
    Filed: April 25, 2016
    Publication date: December 1, 2016
    Inventors: Bruce P. Lee, Jeffrey L. Dalsin, John L. Murphy, Laura Vollenweider, Arinne N. Lyman, Fangmin Xu, Jediah White, William D. Lew, Michael Brodie
  • Adhesive compounds and methods use for hernia repair
    Patent number: 9320826
    Abstract: The invention describes new synthetic medical adhesives and films which exploit the key components of natural marine mussel adhesive proteins.
    Type: Grant
    Filed: November 9, 2011
    Date of Patent: April 26, 2016
    Assignee: KENSEY NASH CORPORATION
    Inventors: Bruce P. Lee, Jeffrey L. Dalsin, John L. Murphy, Laura Vollenweider, Arinne N. Lyman, Fangmin Xu, Jediah White, William D. Lew, Michael Brodie
  • Peg-based adhesive phenylic derivatives and methods of synthesis and use
    Publication number: 20160032047
    Abstract: The invention provides compositions that use phenylic derivatives to provide adhesive properties. Selection of phenylic derivatives with linkers or linking groups, and the linkages between the linkers or linking groups with polyalkylene oxides, provided herein may be configured to control curing time, biodegradation and/or swelling.
    Type: Application
    Filed: March 14, 2014
    Publication date: February 4, 2016
    Inventors: John L MURPHY, Jeffrey L DALSIN, Arinne N LYMAN, Christopher P RADANO
  • Multi-armed catechol compound blends
    Patent number: 8916652
    Abstract: The invention describes families of compounds that utilize multihydroxyl phenyl groups to provide adhesive properties. Selection of the multihydroxy phenyl group along with linkers or linking groups and the linkages between the linkers or linking groups with polyalkylene oxides, provides materials that can be engineered to afford controllable curing time, biodegradation and/or swelling.
    Type: Grant
    Filed: February 20, 2012
    Date of Patent: December 23, 2014
    Assignee: Kensey Nash Corporation
    Inventors: Jeffrey L. Dalsin, Bruce P. Lee, Laura Vollenweider, Sunil Silvary, John L. Murphy, Fangmin Xu, Amanda Spitz, Arinne Lyman
  • Surface independent, surface-modifying, multifunctional coatings and applications thereof
    Patent number: 8911831
    Abstract: The invention provides surface treatments that reduce or eliminate marine biofouling of various surfaces. A surface that is to be subjected to a marine environment can be treated with a mPEG-DOPA. The treated surface is thus rendered less susceptible to fouling of the surface.
    Type: Grant
    Filed: June 3, 2010
    Date of Patent: December 16, 2014
    Assignee: Northwestern University
    Inventors: Phillip B. Messersmith, Haeshin Lee, Andrea R. Statz, Bruce P. Lee, Jeffrey L. Dalsin, Daniel Sherman
  • DOPA-functionalized, branched, poly(aklylene oxide) adhesives
    Patent number: 8673286
    Abstract: The invention describes DOPA functionalized, branched, polyalkylene oxide materials that are useful as adhesives.
    Type: Grant
    Filed: April 8, 2008
    Date of Patent: March 18, 2014
    Assignee: Northwestern University
    Inventors: Phillip B. Messersmith, Jeffrey L. Dalsin, Bruce P. Lee, Sean A. Burke
  • MONO-LAYER THIN FILM ADHESIVE COMPOUNDS AND METHODS OF SYNTHESIS AND USE
    Publication number: 20140030944
    Abstract: The invention relates provides synthetic medical adhesives which exploit plant derivatives to form covalent bonds with amines and thiols on tissue surfaces.
    Type: Application
    Filed: July 25, 2013
    Publication date: January 30, 2014
    Applicant: KNC NER ACQUISITION SUB, INC.
    Inventors: John L. Murphy, Jeffrey L. Dalsin, Arinne N. Lyman, Laura L. Vollenweider, Joel L. Broussard, Neil Winterbottom, Justin T. Koepsel
  • Bioadhesive constructs
    Patent number: 8383092
    Abstract: The invention describes substrates, such as prosthetics, films, nonwovens, meshes, etc. that are treated with a bioadhesive. The bioadhesive includes polymeric substances that have phenyl moieties with at least two hydroxyl groups. The bioadhesive constructs can be used to treat and repair, for example, hernias and damaged tendons.
    Type: Grant
    Filed: September 28, 2009
    Date of Patent: February 26, 2013
    Assignee: KNC NER Acquisition Sub, Inc.
    Inventors: Bruce P. Lee, Laura Vollenweider, John L. Murphy, Fangmin Xu, Jeffrey L. Dalsin, Jeanne Virosco, William Lew, Jed White
  • MULTI-ARMED CATECHOL COMPOUND BLENDS
    Publication number: 20120149849
    Abstract: The invention describes families of compounds that utilize multihydroxyl phenyl groups to provide adhesive properties. Selection of the multihydroxy phenyl group along with linkers or linking groups and the linkages between the linkers or linking groups with polyalkylene oxides, provides materials that can be engineered to afford controllable curing time, biodegradation and/or swelling.
    Type: Application
    Filed: February 20, 2012
    Publication date: June 14, 2012
    Applicant: KNC NER ACQUISITION SUB, INC.
    Inventors: Jeffrey L. Dalsin, Bruce P. Lee, Laura Vollenweider, Sunil Silvary, John L. Murphy, Fangmin Xu, Amanda Spitz, Arinne Lyman
  • ADHESIVE COMPOUNDS AND METHODS USE FOR HERNIA REPAIR
    Publication number: 20120116424
    Abstract: The invention describes new synthetic medical adhesives and films which exploit the key components of natural marine mussel adhesive proteins.
    Type: Application
    Filed: November 9, 2011
    Publication date: May 10, 2012
    Applicant: KNC NER ACQUISITION SUB, INC.
    Inventors: Bruce P. Lee, Jeffrey L. Dalsin, John L. Murphy, Laura Vollenweider, Arinne N. Lyman, Fangmin Xu, Jediah White, William D. Lew, Michael Brodie
  • Multi-armed catechol compound blends
    Patent number: 8119742
    Abstract: The invention describes families of compounds that utilize multihydroxyl phenyl groups to provide adhesive properties. Selection of the multihydroxy phenyl group along with linkers or linking groups and the linkages between the linkers or linking groups with polyalkylene oxides, provides materials that can be engineered to afford controllable curing time, biodegradation and/or swelling.
    Type: Grant
    Filed: September 28, 2009
    Date of Patent: February 21, 2012
    Assignee: KNC Ner Acquisition Sub, Inc.
    Inventors: Jeffrey L. Dalsin, Bruce P. Lee, Laura Vollenweider, Sunil Silvary, John L. Murphy, Fangmin Xu, Amanda Spitz, Arinne Lyman
  • BIOADHESIVE COMPOUNDS AND METHODS OF SYNTHESIS AND USE
    Publication number: 20120016390
    Abstract: The invention describes new synthetic medical adhesives and antifouling coatings which exploit the key components of natural marine mussel adhesive proteins.
    Type: Application
    Filed: July 15, 2011
    Publication date: January 19, 2012
    Applicant: KNC NER ACQUISITION SUB, INC.
    Inventors: Bruce P. Lee, John L. Murphy, Laura Vollenweider, Jeffrey L. Dalsin, Arinne N. Lyman
  • BIOADHESIVE CONSTRUCTS WITH POLYMER BLENDS
    Publication number: 20120003888
    Abstract: The invention describes substrates, such as prosthetics, films, nonwovens, meshes, etc. that are treated with a bioadhesive polymer blend. The bioadhesive includes polymeric substances that have phenyl moieties with at least two hydroxyl groups. The bioadhesive blend constructs can be used to treat and repair, for example, hernias and damaged tendons.
    Type: Application
    Filed: February 5, 2010
    Publication date: January 5, 2012
    Applicant: KNC NER ACQUISITION SUB, INC.
    Inventors: Bruce P. Lee, Jeffrey L. Dalsin, Laura Vollenweider, John L. Murphy, Fangmin Xu
  • COATINGS FOR PREVENTION OF BIOFILMS
    Publication number: 20110130465
    Abstract: This invention is directed to a method to reduce microbial fouling on a surface. The present invention provides antifouling coatings similar to the protein glues secreted by marine mussels for adhesion to underwater substrates.
    Type: Application
    Filed: November 29, 2010
    Publication date: June 2, 2011
    Applicant: NERITES CORPORATION
    Inventors: Jeffrey L. Dalsin, Arinne N. Lyman
  • Surface Independent, Surface-Modifying, Multifunctional Coatings and Applications Thereof
    Publication number: 20100330025
    Abstract: The invention provides surface treatments that reduce or eliminate marine biofouling of various surfaces. A surface that is to be subjected to a marine environment can be treated with a mPEG-DOPA. The treated surface is thus rendered less susceptible to fouling of the surface.
    Type: Application
    Filed: June 3, 2010
    Publication date: December 30, 2010
    Applicant: Northwestern University
    Inventors: Phillip B. Messersmith, Andrea R. Statz Sloan, Bruce P. Lee, Jeffrey L. Dalsin, Daniel Sherman, Haeshin Lee
  • BIOADHESIVE CONSTRUCTS
    Publication number: 20100137902
    Abstract: The invention describes substrates, such as prosthetics, films, nonwovens, meshes, etc. that are treated with a bioadhesive. The bioadhesive includes polymeric substances that have phenyl moieties with at least two hydroxyl groups. The bioadhesive constructs can be used to treat and repair, for example, hernias and damaged tendons.
    Type: Application
    Filed: September 28, 2009
    Publication date: June 3, 2010
    Applicant: NERITES CORPORATION
    Inventors: Bruce P. Lee, Laura Vollenweider, John L. Murphy, Fangmin Xu, Jeffrey L. Dalsin, Jeanne Virosco, William Lew, Jed White
  • BIOADHESIVE CONSTRUCTS
    Publication number: 20100137903
    Abstract: The invention describes substrates, such as prosthetics, films, nonwovens, meshes, etc. that are treated with a bioadhesive. The bioadhesive includes polymeric substances that have phenyl moieties with at least two hydroxyl groups. The bioadhesive constructs can be used to treat and repair, for example, hernias and damaged tendons.
    Type: Application
    Filed: September 28, 2009
    Publication date: June 3, 2010
    Applicant: NERITES CORPORATION
    Inventors: Bruce P. Lee, Laura Vollenweider, John L. Murphy, Fangmin Xu, Jeffrey L. Dalsin, Jeanne Virosco, William Lew, Jed White
  • MULTI-ARMED CATECHOL COMPOUND BLENDS
    Publication number: 20100113828
    Abstract: The invention describes families of compounds that utilize multihydroxyl phenyl groups to provide adhesive properties. Selection of the multihydroxy phenyl group along with linkers or linking groups and the linkages between the linkers or linking groups with polyalkylene oxides, provides materials that can be engineered to afford controllable curing time, biodegradation and/or swelling.
    Type: Application
    Filed: September 28, 2009
    Publication date: May 6, 2010
    Applicant: NERITES CORPORATION
    Inventors: Jeffrey L. Dalsin, Bruce P. Lee, Laura Vollenweider, Sunil Silvary, John L. Murphy, Fangmin Xu, Amanda Spitz, Arinne Lyman