Patents by Inventor Jeffrey L Mooney
Jeffrey L Mooney has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).
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Patent number: 10154779Abstract: An illuming device for use in medically illuminating tissue of interest within a patient generally includes a light diffusing optical fiber and an at least partially optically opaque sheath that is mounted over the fiber for selective, sliding movement along the length thereof. By sliding the sheath relative to the optical fiber after it has been inserted into a patient to illuminate a particular area of tissue, the length, size, and/or shape of the light that is exposed to the tissue can be selectively controlled. Such in situ variation of the properties of the exposed light permit use of a single instrument and a single procedure regardless of variation in the size and shape of the diseased tissue being medically treated.Type: GrantFiled: March 17, 2016Date of Patent: December 18, 2018Assignee: CORNING INCORPORATEDInventors: William Spencer Klubben, III, Jeffrey L Mooney, Peter Gerard Wigley
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Publication number: 20160278622Abstract: An illuming device for use in medically illuminating tissue of interest within a patient generally includes a light diffusing optical fiber and an at least partially optically opaque sheath that is mounted over the fiber for selective, sliding movement along the length thereof. By sliding the sheath relative to the optical fiber after it has been inserted into a patient to illuminate a particular area of tissue, the length, size, and/or shape of the light that is exposed to the tissue can be selectively controlled. Such in situ variation of the properties of the exposed light permit use of a single instrument and a single procedure regardless of variation in the size and shape of the diseased tissue being medically treated.Type: ApplicationFiled: March 17, 2016Publication date: September 29, 2016Inventors: William Spencer Klubben, III, Jeffrey L. Mooney, Peter Gerard Wigley
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Patent number: 6682919Abstract: The invention provides FabH polypeptides and polynucleotides encoding FabH polypeptides and methods for producing such polypeptides by recombinant techniques. Also provided are methods for utilizing FabH polypeptides to screen for antibacterial compounds.Type: GrantFiled: November 14, 1997Date of Patent: January 27, 2004Assignee: SmithKline Beecham CorporationInventors: Christine Debouck, Daniel Robert Gentry, Deborah Dee Jaworski, John Timothy Londsdale, Jeffrey L Mooney, David John Payne, Stewart Campbell Pearson, Lisa Kathleen Schilling, Glenn Scott Van Aller, Min Wang, Yi Yi Zhong
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Publication number: 20030113710Abstract: The present invention provides methods for identifying genes essential to the growth of an organism using a grid prepared from a genomic library of a selected organism. Genes identified as essential by this method and proteins encoded thereby are also provided. In addition, methods of using these genes and proteins encoded thereby are disclosed.Type: ApplicationFiled: December 6, 2002Publication date: June 19, 2003Inventors: Christine Marie Debouck, Jeffrey L. Mooney
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Patent number: 6548281Abstract: The invention provides Histidine Kinase polypeptides and polynucleotides encoding Histidine Kinase polypeptides and methods for producing such polypeptides by recombinant techniques. Also provided are methods for utilizing Histidine Kinase polypeptides to screen for antibacterial compounds.Type: GrantFiled: August 18, 2000Date of Patent: April 15, 2003Assignee: SmithKline Beecham CorporationInventors: Karen M O'Dwyer, Deborah D Jaworski, Jeffrey L Mooney, Lisa K Shilling, John Peter Throup, Nicola Gail Wallis, Yi Yi Zhong, Min Wang
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Publication number: 20020168634Abstract: The present invention provides methods for identifying genes essential to the growth of an organism using a grid prepared from a genomic library of a selected organism. Genes identified as essential by this method and proteins encoded thereby are also provided. In addition, methods of using these genes and proteins encoded thereby are disclosed.Type: ApplicationFiled: May 5, 1999Publication date: November 14, 2002Inventors: CHRISTINE MARIE DEBOUCK, JEFFREY L MOONEY
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Publication number: 20010034331Abstract: Human H218 polypeptides and polynucleotides and methods for producing such polypeptides by recombinant techniques are disclosed. Also disclosed are methods for utilizing Human H218 polypeptides and polynucleotides in therapy, and diagnostic assays for such.Type: ApplicationFiled: January 26, 2001Publication date: October 25, 2001Inventors: Derk J. Bergsma, Nabil Elshourbagy, Pamela Lane, Xiaotong Li, Jeffrey L. Mooney, Ping Tsui
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Patent number: 6294364Abstract: Fatty Acid Synthase polypeptides and polynucleotides and methods for producing such polypeptides by recombinant techniques are disclosed. Also disclosed are methods for utilising Fatty Acid Synthase polypeptides and polynucleotides in therapy, and diagnostic assays for such.Type: GrantFiled: March 3, 1999Date of Patent: September 25, 2001Assignee: SmithKline Beecham CorporationInventors: Derk J Bergsma, Conrad Chapman, Megan E Depiera, Catherine E Ellis, John Lonsdale, Jeffrey L Mooney
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Patent number: 6245550Abstract: EF-7 polypeptides and polynucleotides and methods for producing such polypeptides by recombinant techniques are disclosed. Also disclosed are methods for utilizing EF-7 polypeptides and polynucleotides in therapy, and diagnostic assays for such.Type: GrantFiled: March 20, 1998Date of Patent: June 12, 2001Assignee: SmithKline Beecham CorporationInventors: Sherin S Abdel-Meguid, Rajeev Aurora, Derk J Bergsma, Catherine E Ellis, Stephanie F Guerrera, Preston Hensley, Jeffrey L Mooney, George D Rose, Peter R Young, Yuan Zhu
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Patent number: 6204042Abstract: The invention provides GlmU polypeptides and polynucleotides encoding GlmU polypeptides and methods for producing such polypeptides by recombinant techniques. Also provided are methods for utilizing GlmU polypeptides to screen for antibacterial compounds.Type: GrantFiled: May 10, 1999Date of Patent: March 20, 2001Assignee: SMithKline Beecham CorporationInventors: Christine Debouck, Deborah Dee Jaworski, Jeffrey L Mooney, Lisa Kathleen Shilling, Nicola Gail Wallis, Min Wang, Yi Yi Zhong
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Patent number: 6187544Abstract: The present invention provides a method for high throughput cloning of full length cDNA sequences using a pooling strategy. This method uses a plurality of clone arrays prepared from cDNA libraries which have been preferably enriched for 5 ′ mRNA sequences and size fractionated into several discrete ranges (sub-libraries). These arrays are used to rapidly identify the full length cDNA sequence for a DNA segment of interest.Type: GrantFiled: November 3, 1999Date of Patent: February 13, 2001Assignee: SmithKline Beecham CorporationInventors: Derk Jon Bergsma, Jeffrey L Mooney
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Patent number: 6043071Abstract: The invention provides GlmU polypeptides and polynucleotides encoding GlmU polypeptides and methods for producing such polypeptides by recombinant techniques. Also provided are methods for utilizing GlmU polypeptides to screen for antibacterial compounds.Type: GrantFiled: November 17, 1997Date of Patent: March 28, 2000Assignee: SmithKline Beecham CorporationInventors: Christine DeBouck, Deborah Dee Jaworski, Jeffrey L Mooney, Lisa Kathleen Shilling, Nicola Gail Wallis, Min Wang, Yi Yi Zhong
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Patent number: 5955308Abstract: HEOAD54 polypeptides and polynucleotides and methods for producing such polypeptides by recombinant techniques are disclosed. Also disclosed are methods for utilizing HEOAD54 polypeptides and polynucleotides in the design of protocols for the treatment of infections such as bacterial, fungal, protozoan and viral infections, particularly infections caused by HIV-1 or HIV-2; pain; cancers; anorexia; bulimia; asthma; Parkinson's disease; acute heart failure; hypotension; hypertension; urinary retention; osteoporosis; angina pectoris; myocardial infraction; ulcers;astma; allergies; benign prostatic hypertrophy; and psychotic and neurological disorders, including anxiety, schizophrenia, manic depression, delirium, dementia, severe mental retardation and dyskinesias, such as Huntington's disease or Gilles dela Tourettt's syndrome, among others, and diagnostic assays for such conditions.Type: GrantFiled: October 23, 1997Date of Patent: September 21, 1999Assignee: SmithKline Beecham CorporationInventors: Derk J Bergsma, Wendy S Halsey, Jeffrey L Mooney, Ganesh M Sathe