Patents by Inventor Jeffrey Lance Kizer

Jeffrey Lance Kizer has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • Methods for increasing isoprenoid and isoprenoid precursor production by modulating fatty acid levels
    Patent number: 8114645
    Abstract: The present invention provides methods of increasing production of an isoprenoid or an isoprenoid precursor in a host cell, the methods generally involving modulating the level of activity of a fatty acid biosynthetic pathway enzyme in the host cell and/or culturing the host cell in a culture medium comprising a fatty acid or a compound that can be metabolized in a cell or broken down in the medium to yield a fatty acid and/or culturing the host cell in a culture medium having increased osmolarity.
    Type: Grant
    Filed: May 17, 2007
    Date of Patent: February 14, 2012
    Assignee: The Regents of the University of California
    Inventors: Douglas J. Pitera, Jack D. Newman, Jeffrey Lance Kizer, Jay D. Keasling, Brian F. Pfleger
  • METHODS FOR INCREASING ISOPRENOID AND ISOPRENOID PRECURSOR PRODUCTION BY MODULATING FATTY ACID LEVELS
    Publication number: 20100055754
    Abstract: The present invention provides methods of increasing production of an isoprenoid or an isoprenoid precursor in a host cell, the methods generally involving modulating the level of activity of a fatty acid biosynthetic pathway enzyme in the host cell and/or culturing the host cell in a culture medium comprising a fatty acid or a compound that can be metabolized in a cell or broken down in the medium to yield a fatty acid and/or culturing the host cell in a culture medium having increased osmolarity.
    Type: Application
    Filed: May 17, 2007
    Publication date: March 4, 2010
    Inventors: Douglas J. Pitera, Jack D. Newman, Jeffrey Lance Kizer, Jay D. Keasling, Brian F. Pfleger
  • GENETICALLY MODIFIED HOST CELLS FOR INCREASED P450 ACTIVITY LEVELS AND METHODS OF USE THEREOF
    Publication number: 20080233623
    Abstract: The present invention provides genetically modified host cells that exhibit modified activity levels of one or more gene products such that, when a cytochrome P450 enzyme is produced in the genetically modified host cell, the modified activity levels of the one or more gene products provide for enhanced production and/or activity of the cytochrome P450 enzyme. The present invention provides methods of producing a cytochrome P450 enzyme in a host cell, generally involving culturing a subject genetically modified host cell in a suitable culture medium. The present invention further provides methods of producing a product of a P450-dependent oxidation, generally involving culturing a subject genetically modified host cell in a suitable culture medium.
    Type: Application
    Filed: January 29, 2008
    Publication date: September 25, 2008
    Inventors: Michelle Chia-Yu Chang, Rachel A. Krupa, Jeffrey Lance Kizer, John R. Haliburton, Mario Ouellet, Jeffrey Alan Dietrich, Jay D. Keasling