Abstract: Systems and methods are provided for processing and analyzing signals reflecting, physiologic processes and events in a monitored subject, especially cardio-pulmonary signals. The input signals are analyzed by in a physiological domain by creating structured data representing the physiological events reflected in the signals. Preferably, first, primitive event objects are created representing physiologically-significant portions of these input signals; second, the primitive event objects are grouped into primary event objects representing actual physiologic processes and events. Next, all objects are stored in databases, and organized in containers for efficient searching. Information may be retrieved by creating view objects which associate physiologic event objects having selected properties specified directly in physiological terms.