Abstract: A cargo seal assembly structured to maintain one or more doors on a cargo container in a closed and latched position comprising an elongated flexible material segment having a distal end, a proximal end and an intermediate portion extending therebetween. The flexible material segment is disposed and structured to extend in surrounding relation to the lock rods an concurrently into sealing engagement with the latch assembly. A lock body is attached to the flexible material segment at a location which prevents removal of the material segment from its operative position. As such unauthorized access to the interior of the cargo container can only be accomplished by destructive separation of the flexible material segment at two separate, spaced apart locations along its length. A single identifying indicia is disposed on the flexible material segment or an operative component associated therewith.