Patents by Inventor Jeffrey M. Arbeit

Jeffrey M. Arbeit has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • Expression of human estrogen receptors in transgenic mice
    Patent number: 6586655
    Abstract: The present invention relates to improved compositions and methods for assaying the efficacy of novel drugs functioning either as agonists or antagonists at nuclear receptors. In particular, the invention provides transgenic non-human animals comprising a human steroid hormone receptor gene operably linked to a promoter which directs expression of the steroid hormone receptor gene in an epithelial cell of the non-human animals.
    Type: Grant
    Filed: August 2, 1999
    Date of Patent: July 1, 2003
    Assignee: The Regents of the University of California
    Inventors: Jeffrey M. Arbeit, Peter J. Kushner, Rosalie M. Uht, Birgit Anderegg
  • EXPRESSION OF HUMAN ESTROGEN RECEPTORS IN TRANSGENIC MICE
    Publication number: 20030056230
    Abstract: The present invention relates to improved compositions and methods for assaying the efficacy of novel drugs functioning either as agonists or antagonists at nuclear receptors. In particular, the invention provides transgenic non-human animals comprising a human steroid hormone receptor gene operably linked to a promoter which directs expression of the steroid hormone receptor gene in an epithelial cell of the non-human animals.
    Type: Application
    Filed: August 2, 1999
    Publication date: March 20, 2003
    Inventors: JEFFREY M. ARBEIT, PETER J. KUSHNER, ROSALIE M.. UHT, BIRGIT ANDEREGG
  • Transgenic mice expressing HPV early region oncogene develop progressive cervico-vaginal neoplasia
    Patent number: 5709844
    Abstract: The present invention relates to improved models for progressive epithelial neoplasias and methods for their use. In particular, the invention provides transgenic mice comprising a human papilloma virus early region oncogene operably linked to a promoter which directs expression of the oncogene in a transient amplifying cell in the mice.
    Type: Grant
    Filed: June 7, 1995
    Date of Patent: January 20, 1998
    Assignee: The Regents of the University of California
    Inventors: Jeffrey M. Arbeit, Douglas Hanahan
  • Transgenic mice expressing HPV early region oncogene develop progressive epithelial neoplasia
    Patent number: 5698764
    Abstract: The present invention relates to improved models for progressive epithelial neoplasias and methods for their use. In particular, the invention provides transgenic mice comprising a human papilloma virus early region oncogene operably linked to a promoter which directs expression of the oncogene in a transient amplifying cell in the mice.
    Type: Grant
    Filed: June 9, 1994
    Date of Patent: December 16, 1997
    Assignees: The Regents of the University of California, The United States of America as represented by the Secretary of Health and Human Services
    Inventors: Jeffrey M. Arbeit, Douglas Hanahan, Peter M. Howley