Patents by Inventor Jeffrey M. Drazen

Jeffrey M. Drazen has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • Methods for diagnosis, prediction and treatment of asthma and other inflammatory conditions based on eotaxin coding sequence polymorphism
    Patent number: 6949637
    Abstract: Methods and compositions for diagnosing and treating asthma are provided. The methods involve the discovery of a correlation between an eotaxin gene polymorphism and the ocurrence of asthma.
    Type: Grant
    Filed: April 14, 2003
    Date of Patent: September 27, 2005
    Assignees: Brigham and Women's Hospital, Inc., The General Hospital Corporation
    Inventors: Craig M. Lilly, Andrew D. Luster, Jeffrey M. Drazen
  • Methods for diagnosis, prediction and treatment of asthma and other inflammatory conditions based on eotaxin coding sequence polymorphism
    Publication number: 20030165980
    Abstract: Methods and compositions for diagnosing and treating asthma are provided. The methods involve the discovery of a correlation between an eotaxin gene polymorphism and the ocurrence of asthma.
    Type: Application
    Filed: April 14, 2003
    Publication date: September 4, 2003
    Applicant: The Brigham and Women's Hospital, Inc.
    Inventors: Craig M. Lilly, Andrew D. Luster, Jeffrey M. Drazen
  • Methods for diagnosis, prediction and treatment of asthma and other inflammatory conditions based on eotaxin coding sequence polymorphism
    Patent number: 6548245
    Abstract: Methods and compositions for diagnosing and treating asthma are provided. The methods involve the discovery of a correlation between an eotaxin gene polymorphism and the occurrence of asthma.
    Type: Grant
    Filed: May 12, 1998
    Date of Patent: April 15, 2003
    Assignee: Brigham and Women's Hospital, Inc.
    Inventors: Craig M. Lilly, Andrew D. Luster, Jeffrey M. Drazen
  • Diagnosing asthma patients predisposed to adverse beta-agonist reactions
    Publication number: 20020119474
    Abstract: The present invention provides a novel method for identifying individuals who are likely to have negative responses to regular administration of &bgr;-agonists. The invention also provides kits useful for this purpose.
    Type: Application
    Filed: November 21, 2001
    Publication date: August 29, 2002
    Inventors: Jeffrey M. Drazen, Vern Chinchilli, Richard Martin, Robert Lemanske, Jean G. Ford, James E. Fish, Homer Boushey
  • 5-Lipoxygenase gene polymorphisms and their use in classifying patients
    Patent number: 6355434
    Abstract: The present invention provides identification of sequence polymorphisms in the 5-lipoxygenase gene that are present in general and asthmatic populations. The invention provides methods associated with correlating such polymorphisms with asthmatic phenotype and responsiveness to therapy. In particular, the invention demonstrates that individuals with reduced 5-lipoxygenase expression (or activity) are less responsive to treatment with 5-lipoxygenase inhibiters.
    Type: Grant
    Filed: July 17, 2000
    Date of Patent: March 12, 2002
    Assignee: Brigham & Women's Hospital
    Inventors: Jeffrey M. Drazen, Kwang-Ho In, Koichiro Asano, David Beier, James Grobholz
  • Diagnosing asthma patients predisposed to adverse .beta.-agonist reactions
    Patent number: 6156503
    Abstract: The present invention provides a novel method for identifying individuals who are likely to have negative responses to regular administration of .beta.-agonists. The invention also provides kits useful for this purpose.
    Type: Grant
    Filed: March 3, 1997
    Date of Patent: December 5, 2000
    Assignees: The Regents of the University of California, The Trustees of Columbia University in the City of New York, The Penn State Research Foundation, National Jewish Medical and Research Center, Wisconsin Alumni Research Center, Thomas Jefferson University, Brigham and Women's Hospital
    Inventors: Jeffrey M. Drazen, Vern Chinchilli, Richard Martin, Robert Lemanske, Jean G. Ford, James E. Fish, Homer Boushey
  • Identification of asthma patients who are candidates for effective treatment with 5-lipoxygenase inhibitors
    Patent number: 6090547
    Abstract: The present invention provides identification of sequence polymorphisms in the 5-lipoxygenase gene that are present in general and asthmatic populations. The invention provides methods associated with correlating such polymorphisms with asthmatic phenotype and responsiveness to therapy. In particular, the invention demonstrates that individuals with reduced 5-lipoxygenase expression (or activity) are less responsive to treatment with 5-lipoxygenase inhibiters.
    Type: Grant
    Filed: April 25, 1997
    Date of Patent: July 18, 2000
    Assignee: Brigham & Women's Hospital
    Inventors: Jeffrey M. Drazen, Kwang-Ho In, Koichiro Asano, David Beier, James Grobholz