Patents by Inventor Jeffrey M. Gillberg
Jeffrey M. Gillberg has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).
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Patent number: 11819699Abstract: VfA cardiac therapy uses an implantable medical device or system. The implantable medical device includes a tissue-piercing electrode implanted in the basal and/or septal region of the left ventricular myocardium of the patient's heart from the triangle of Koch region of the right atrium through the right atrial endocardium and central fibrous body. The device may include a right atrial electrode, a right atrial motion detector, or both. The device may be implanted completely within the patient's heart or may use one or more leads to implant electrodes in the patient's heart. The device may be used to provide cardiac therapy, including single or multiple chamber pacing, atrioventricular synchronous pacing, asynchronous pacing, triggered pacing, cardiac resynchronization pacing, or tachycardia-related therapy. A separate medical device may be used to provide some functionality for cardiac therapy, such as sensing, pacing, or shock therapy.Type: GrantFiled: December 22, 2021Date of Patent: November 21, 2023Assignee: Medtronic, Inc.Inventors: Zhongping Yang, Thomas A. Anderson, Brian P. Colin, William J. Clemens, Subham Ghosh, Jeffrey M. Gillberg, Maurice T. I Verbeek, Toine Camps, Lilian Kornet, Berthold Stegemann, Jean Rutten
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Patent number: 11813464Abstract: Systems, interfaces, and methods are described herein related to the evaluation of a patient's cardiac conduction system and evaluation of cardiac conduction system pacing therapy being delivered to the patient's cardiac conduction system. Evaluation of the patient's cardiac conduction system may utilize a plurality of breakthrough maps to determine where a cardiac conduction system block may be located. Evaluation of cardiac conduction system pacing therapy may utilize various electrical heterogeneity information monitored before and during delivery of cardiac conduction system pacing therapy.Type: GrantFiled: June 29, 2021Date of Patent: November 14, 2023Assignee: Medtronic, Inc.Inventors: Ruth N. Klepfer, Manfred Justen, Subham Ghosh, Jeffrey M. Gillberg
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Patent number: 11642032Abstract: A method includes determining that a patient has heart failure with preserved ejection fraction (HFpEF); configuring a cardiovascular (CV) model using patient characterization data; determining one or more therapy parameters using output data of the CV model; and administering HFpEF therapy based on the one or more therapy parameters.Type: GrantFiled: December 14, 2020Date of Patent: May 9, 2023Assignee: Medtronic, Inc.Inventors: Jeffrey M. Gillberg, Troy E. Jackson, Richard Cornelussen
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Publication number: 20230034970Abstract: This disclosure is directed to a medical system and technique for a filter-based approach to arrhythmia detection. In one example, the medical system comprises one or more sensors configured to sense physiological parameter(s); sensing circuitry configured to generate patient data based on the sensed physiological parameter(s), the patient data comprising signal data to represent cardiac activity of the patient; and processing circuitry configured to: detect a cardiac arrhythmia for the patient based on a classification of the signal data in accordance with a machine learning model, wherein the machine learning model comprises filter(s) for at least one portion of the signal data, wherein the at least one filter corresponds to a feature set that maps to the cardiac activity represented by the portion(s) of the signal data; and generate for display output data indicative of a positive detection of the cardiac arrhythmia.Type: ApplicationFiled: July 28, 2021Publication date: February 2, 2023Inventors: Ya-Jian Cheng, Eduardo N. Warman, Jeffrey M. Gillberg, Abhijit Kadrolkar, Shantanu Sarkar, Kevin T. Ousdigian
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Publication number: 20220370800Abstract: A medical device senses cardiac electrical signals including T-waves attendant to ventricular myocardial repolarizations and detects a T-wave template condition associated with non-pathological changes in T-wave morphology. The device generates a T-wave template from T-waves sensed by the sensing circuit during the T-wave template condition. After generating the T-wave template, the device acquires a T-wave signal from the cardiac electrical signal and compares the acquired T-wave signal to the T-wave template. The device detects a pathological event in response to the acquired T-wave signal not matching the T-wave template.Type: ApplicationFiled: July 22, 2022Publication date: November 24, 2022Inventors: Inna A. PIKULENKO, Gary L. BERG, Jeffrey M. GILLBERG
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Patent number: 11439830Abstract: A medical device senses cardiac electrical signals including T-waves attendant to ventricular myocardial repolarizations and detects a T-wave template condition associated with non-pathological changes in T-wave morphology. The device generates a T-wave template from T-waves sensed by the sensing circuit during the T-wave template condition. After generating the T-wave template, the device acquires a T-wave signal from the cardiac electrical signal and compares the acquired T-wave signal to the T-wave template. The device detects a pathological event in response to the acquired T-wave signal not matching the T-wave template.Type: GrantFiled: March 20, 2020Date of Patent: September 13, 2022Assignee: Medtronic, Inc.Inventors: Inna A. Pikulenko, Gary L. Berg, Jeffrey M. Gillberg
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Patent number: 11400296Abstract: VfA cardiac therapy uses an implantable medical device or system. The implantable medical device includes a tissue-piercing electrode implanted in the basal and/or septal region of the left ventricular myocardium of the patient's heart from the triangle of Koch region of the right atrium through the right atrial endocardium and central fibrous body. The device may include a right atrial electrode, a right atrial motion detector, or both. The device may be implanted completely within the patient's heart or may use one or more leads to implant electrodes in the patient's heart. The device may be used to provide cardiac therapy, including single or multiple chamber pacing, atrioventricular synchronous pacing, asynchronous pacing, triggered pacing, cardiac resynchronization pacing, or tachycardia-related therapy. A separate medical device may be used to provide some functionality for cardiac therapy, such as sensing, pacing, or shock therapy.Type: GrantFiled: March 22, 2019Date of Patent: August 2, 2022Assignee: Medtronic, Inc.Inventors: Zhongping Yang, Thomas A. Anderson, Brian P. Colin, William J. Clemens, Subham Ghosh, Jeffrey M. Gillberg, Maurice T. I. Verbeek, Toine Camps, Lilian Kornet, Berthold Stegemann, Jean Rutten
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Patent number: 11305124Abstract: A medical device system and associated method predict a patient response to a cardiac therapy. The system includes for delivering cardiac pacing pulses to a patient's heart coupled to a cardiac sensing module and a cardiac pacing module for generating cardiac pacing pulses and controlling delivery of the pacing pulses at multiple pace parameter settings. An acoustical sensor obtains heart sound signals. A processor is enabled to receive the heart sound signals, derive a plurality of heart sound signal parameters from the heart sound signals, and determine a trend of each of the plurality of heart sound signal parameters with respect to the plurality of pace parameter settings. An external display is configured to present the trend of at least one heart sound parameter with respect to the plurality of pace parameter settings.Type: GrantFiled: August 26, 2019Date of Patent: April 19, 2022Assignee: Medtronic, Inc.Inventors: Xusheng Zhang, Jeffrey M. Gillberg, Thomas J. Mullen
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Publication number: 20220111216Abstract: VfA cardiac therapy uses an implantable medical device or system. The implantable medical device includes a tissue-piercing electrode implanted in the basal and/or septal region of the left ventricular myocardium of the patient's heart from the triangle of Koch region of the right atrium through the right atrial endocardium and central fibrous body. The device may include a right atrial electrode, a right atrial motion detector, or both. The device may be implanted completely within the patient's heart or may use one or more leads to implant electrodes in the patient's heart. The device may be used to provide cardiac therapy, including single or multiple chamber pacing, atrioventricular synchronous pacing, asynchronous pacing, triggered pacing, cardiac resynchronization pacing, or tachycardia-related therapy. A separate medical device may be used to provide some functionality for cardiac therapy, such as sensing, pacing, or shock therapy.Type: ApplicationFiled: December 22, 2021Publication date: April 14, 2022Inventors: Zhongping Yang, Thomas A. Anderson, Brian P. Colin, William J. Clemens, Subham Ghosh, Jeffrey M. Gillberg, Maurice T. I. Verbeek, Toine Camps, Lilian Kornet, Berthold Stegemann
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Patent number: 11285312Abstract: Systems and methods are described herein for evaluation and adjustment of a left ventricular assist device (LVAD). The systems and methods may utilize at least a plurality of external electrodes to monitor cardiac electrical activity before and during LVAD therapy. The cardiac electrical activity as well as other information such cardiac sound information may be used to determine and adjust one or more LVAD output parameters such as pump speed.Type: GrantFiled: March 29, 2019Date of Patent: March 29, 2022Assignee: Medtronic, Inc.Inventors: Jeffrey M. Gillberg, Subham Ghosh, Michael F. Hess, Troy E. Jackson
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Publication number: 20220032069Abstract: An electrode apparatus includes a portable amplifier and a plurality of external electrodes to be disposed proximate a patient's skin. A portable computing apparatus is operably coupled to the electrode apparatus. The portable computing apparatus is configured to monitor electrical activity from tissue of a patient using the plurality of external electrodes to generate a plurality of electrical signals over time. The portable computing apparatus is configured to perform at least one of optimizing at least one parameter of the of the implantable pacing device based on the plurality of electrical signals and determining cardiac synchrony based on the plurality of electrical signals.Type: ApplicationFiled: July 26, 2021Publication date: February 3, 2022Inventors: Ruth N. Klepfer, Manfred Justen, Subham Ghosh, Jeffrey M. Gillberg, Trent M. Fischer, Elizabeth A. Schotzko
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Publication number: 20220032070Abstract: Systems, interfaces, and methods are described herein related to the evaluation of a patient's cardiac conduction system and evaluation of cardiac conduction system pacing therapy being delivered to the patient's cardiac conduction system. Evaluation of the patient's cardiac conduction system may utilize a plurality of breakthrough maps to determine where a cardiac conduction system block may be located. Evaluation of cardiac conduction system pacing therapy may utilize various electrical heterogeneity information monitored before and during delivery of cardiac conduction system pacing therapy.Type: ApplicationFiled: June 29, 2021Publication date: February 3, 2022Inventors: Ruth N. Klepfer, Manfred Justen, Subham Ghosh, Jeffrey M. Gillberg
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Publication number: 20220031221Abstract: Cardiac electrical activity is monitored from tissue of the patient using the plurality of external electrodes. One or more cardiac metrics of the patient are generated based on the monitored electrical activity. It is determined whether the patient is a candidate for a cardiac resynchronization therapy (CRT) device based on a first global dyssynchrony metric using the one or more cardiac metrics if the patient has a right bundle branch block. It is determined whether the patient is a candidate for a cardiac resynchronization therapy (CRT) device based on a second global dyssynchrony metric using the one or more cardiac metrics if the patient does not have a right bundle branch block.Type: ApplicationFiled: July 6, 2021Publication date: February 3, 2022Inventors: Ruth N. Klepfer, Manfred Justen, Subham Ghosh, Jeffrey M. Gillberg
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Patent number: 11235159Abstract: VfA cardiac therapy uses an implantable medical device or system. The implantable medical device includes a tissue-piercing electrode implanted in the basal and/or septal region of the left ventricular myocardium of the patient's heart from the triangle of Koch region of the right atrium through the right atrial endocardium and central fibrous body. The device may include a right atrial electrode, a right atrial motion detector, or both. The device may be implanted completely within the patient's heart or may use one or more leads to implant electrodes in the patient's heart. The device may be used to provide cardiac therapy, including single or multiple chamber pacing, atrioventricular synchronous pacing, asynchronous pacing, triggered pacing, cardiac resynchronization pacing, or tachycardia-related therapy. A separate medical device may be used to provide some functionality for cardiac therapy, such as sensing, pacing, or shock therapy.Type: GrantFiled: March 22, 2019Date of Patent: February 1, 2022Assignee: Medtronic, Inc.Inventors: Zhongping Yang, Thomas A. Anderson, Brian P. Colin, William J. Clemens, Subham Ghosh, Jeffrey M. Gillberg, Maurice T. I. Verbeek, Toine Camps, Lilian Kornet, Berthold Stegemann, Jean Rutten
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Publication number: 20210290960Abstract: Techniques for evaluating cardiac electrical dyssynchrony are described. In some examples, an activation time is determined for each of a plurality of torso-surface potential signals. The dispersion or sequence of these activation times may be analyzed or presented to provide variety of indications of the electrical dyssynchrony of the heart of the patient. In some examples, the locations of the electrodes of the set of electrodes, and thus the locations at which the torso-surface potential signals were sensed, may be projected on the surface of a model torso that includes a model heart. The inverse problem of electrocardiography may be solved to determine electrical activation times for regions of the model heart based on the torso-surface potential signals sensed from the patient.Type: ApplicationFiled: June 4, 2021Publication date: September 23, 2021Inventors: Subham Ghosh, Jeffrey M. Gillberg, Robert W. Stadler
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Publication number: 20210196132Abstract: A method includes determining that a patient has heart failure with preserved ejection fraction (HFpEF); configuring a cardiovascular (CV) model using patient characterization data; determining one or more therapy parameters using output data of the CV model; and administering HFpEF therapy based on the one or more therapy parameters.Type: ApplicationFiled: December 14, 2020Publication date: July 1, 2021Inventors: Jeffrey M. Gillberg, Troy E. Jackson, Richard Cornelussen
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Patent number: 11027135Abstract: Techniques for evaluating cardiac electrical dyssynchrony are described. In some examples, an activation time is determined for each of a plurality of torso-surface potential signals. The dispersion or sequence of these activation times may be analyzed or presented to provide variety of indications of the electrical dyssynchrony of the heart of the patient. In some examples, the locations of the electrodes of the set of electrodes, and thus the locations at which the torso-surface potential signals were sensed, may be projected on the surface of a model torso that includes a model heart. The inverse problem of electrocardiography may be solved to determine electrical activation times for regions of the model heart based on the torso-surface potential signals sensed from the patient.Type: GrantFiled: April 30, 2018Date of Patent: June 8, 2021Assignee: MEDTRONIC, INC.Inventors: Subham Ghosh, Jeffrey M. Gillberg, Robert W. Stadler
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Publication number: 20210106832Abstract: Systems and methods are described herein for use in synchronizing electrical activity monitored by a plurality of external electrodes with supplemental cardiac data for use in evaluating a patient's cardiac condition and configuring cardiac therapy. The supplemental cardiac data may include one or more markers indicative of the occurrence of cardiac events and/or data representative of representative of at least one of cardiac electrical signals, cardiac sounds, cardiac pressures, blood flow, and an estimated instantaneous flow waveform provided by a left ventricular assist device.Type: ApplicationFiled: September 24, 2020Publication date: April 15, 2021Inventors: Subham Ghosh, Jeffrey M. Gillberg, Trent M. Fischer
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Publication number: 20210106227Abstract: Systems, methods, and devices are described herein for evaluation of patient's cardiac condition based on monitored electrical activity from a plurality of external electrodes. Various information such as electrical heterogeneity information may be generated based on the monitored electrical activity, which may be further analyzed to evaluate the patient's cardiac condition. The systems, methods, and devices may provide an indication of whether the patient may benefit from cardiac therapy based on the evaluation of the patient's cardiac condition.Type: ApplicationFiled: September 24, 2020Publication date: April 15, 2021Inventors: Subham Ghosh, Jeffrey M. Gillberg
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Publication number: 20200298002Abstract: A medical device senses cardiac electrical signals including T-waves attendant to ventricular myocardial repolarizations and detects a T-wave template condition associated with non-pathological changes in T-wave morphology. The device generates a T-wave template from T-waves sensed by the sensing circuit during the T-wave template condition. After generating the T-wave template, the device acquires a T-wave signal from the cardiac electrical signal and compares the acquired T-wave signal to the T-wave template. The device detects a pathological event in response to the acquired T-wave signal not matching the T-wave template.Type: ApplicationFiled: March 20, 2020Publication date: September 24, 2020Inventors: Inna A. PIKULENKO, Gary L. BERG, Jeffrey M. GILLBERG