Patents by Inventor Jeffrey M. Sequeira

Jeffrey M. Sequeira has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • Antibodies to the B12-transcobalamin receptor
    Patent number: 9834612
    Abstract: The present invention provides anti-TCblR antibodies and related compositions, which may be used in any of a variety of therapeutic methods for the treatment of cancer, tumors and other proliferative diseases and disorders.
    Type: Grant
    Filed: July 15, 2015
    Date of Patent: December 5, 2017
    Assignee: THE RESEARCH FOUNDATION OF STATE UNIVERSITY OF NEW YORK
    Inventors: Edward V. Quadros, Jeffrey M. Sequeira
  • ANTIBODIES TO THE B12-TRANSCOBALAMIN RECEPTOR
    Publication number: 20160130354
    Abstract: The present invention provides anti-TCblR antibodies and related compositions, which may be used in any of a variety of therapeutic methods for the treatment of cancer, tumors and other proliferative diseases and disorders.
    Type: Application
    Filed: July 15, 2015
    Publication date: May 12, 2016
    Inventors: Edward V. Quadros, Jeffrey M. Sequeira
  • Antibodies to the B12-transcobalamin receptor
    Patent number: 9120858
    Abstract: The present invention provides anti-TCblR antibodies and related compositions, which may be used in any of a variety of therapeutic methods for the treatment of cancer, tumors and other proliferative diseases and disorders.
    Type: Grant
    Filed: July 20, 2012
    Date of Patent: September 1, 2015
    Assignee: The Research Foundation of State University of New York
    Inventors: Edward V. Quadros, Jeffrey M. Sequeira
  • Transcobalamin receptor polypeptides, nucleic acids, and modulators thereof, and related methods of use in modulating cell growth and treating cancer and cobalamin deficiency
    Patent number: 9044461
    Abstract: The present invention provides the amino acid and polynucleotide sequences of the transcobalamin receptor, as well as modulators of the transcobalamin receptor. Accordingly, the present invention provides compositions and methods for the treatment and prevention of diseases and disorders associated with cobalamin deficiency, including compositions and methods that promote cobalamin uptake. In addition, the present invention provides compositions and methods for the detection, treatment, and prevention of diseases associated with deregulated cell growth, including, e.g., cancer and autoimmune disorders, including compositions and methods that inhibit cobalamin uptake.
    Type: Grant
    Filed: August 14, 2013
    Date of Patent: June 2, 2015
    Assignee: The Research Foundation of State University of New York
    Inventors: Edward V. Quadros, Jeffrey M. Sequeira
  • TRANSCOBALAMIN RECEPTOR POLYPEPTIDES, NUCLEIC ACIDS, AND MODULATORS THEREOF, AND RELATED METHODS OF USE IN MODULATING CELL GROWTH AND TREATING CANCER AND COBALAMIN DEFICIENCY
    Publication number: 20140068793
    Abstract: The present invention provides the amino acid and polynucleotide sequences of the transcobalamin receptor, as well as modulators of the transcobalamin receptor. Accordingly, the present invention provides compositions and methods for the treatment and prevention of diseases and disorders associated with cobalamin deficiency, including compositions and methods that promote cobalamin uptake. In addition, the present invention provides compositions and methods for the detection, treatment, and prevention of diseases associated with deregulated cell growth, including, e.g., cancer and autoimmune disorders, including compositions and methods that inhibit cobalamin uptake.
    Type: Application
    Filed: August 14, 2013
    Publication date: March 6, 2014
    Applicant: The Research Foundation of State University of New York
    Inventors: Edward V. Quadros, Jeffrey M. Sequeira
  • Transcobalamin receptor polypeptides, nucleic acids, and modulators thereof, and related methods of use in modulating cell growth and treating cancer and cobalamin deficiency
    Patent number: 8524454
    Abstract: The present invention provides the amino acid and polynucleotide sequences of the transcobalamin receptor, as well as modulators of the transcobalamin receptor. Accordingly, the present invention provides compositions and methods for the treatment and prevention of diseases and disorders associated with cobalamin deficiency, including compositions and methods that promote cobalamin uptake. In addition, the present invention provides compositions and methods for the detection, treatment, and prevention of diseases associated with deregulated cell growth, including, e.g., cancer and autoimmune disorders, including compositions and methods that inhibit cobalamin uptake.
    Type: Grant
    Filed: April 5, 2007
    Date of Patent: September 3, 2013
    Assignee: The Research Foundation of State University of New York
    Inventors: Edward V. Quadros, Jeffrey M. Sequeira
  • ANTIBODIES TO THE B12-TRANSCOBALAMIN RECEPTOR
    Publication number: 20130164309
    Abstract: The present invention provides anti-TCblR antibodies and related compositions, which may be used in any of a variety of therapeutic methods for the treatment of cancer, tumors and other proliferative diseases and disorders.
    Type: Application
    Filed: July 20, 2012
    Publication date: June 27, 2013
    Applicant: The Research Foundation of State University of New York
    Inventors: Edward V. Quadros, Jeffrey M. Sequeira
  • TRANSCOBALAMIN RECEPTOR POLYPEPTIDES, NUCLEIC ACIDS, AND MODULATORS THEREOF, AND RELATED METHODS OF USE IN MODULATING CELL GROWTH AND TREATING CANCER AND COBALAMIN DEFICIENCY
    Publication number: 20100061974
    Abstract: The present invention provides the amino acid and polynucleotide sequences of the transcobalamin receptor, as well as modulators of the transcobalamin receptor. Accordingly, the present invention provides compositions and methods for the treatment and prevention of diseases and disorders associated with cobalamin deficiency, including compositions and methods that promote cobalamin uptake. In addition, the present invention provides compositions and methods for the detection, treatment, and prevention of diseases associated with deregulated cell growth, including, e.g., cancer and autoimmune disorders, including compositions and methods that inhibit cobalamin uptake.
    Type: Application
    Filed: April 5, 2007
    Publication date: March 11, 2010
    Inventors: Edward V. Quadros, Jeffrey M. Sequeira