Patents by Inventor Jeffrey M. Staub
Jeffrey M. Staub has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).
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Publication number: 20240117032Abstract: Affinity constructs to direct insecticidal toxins to insect specific structures of target insects are presented herein. The affinity constructs comprise of at least one affinity molecule that is capable of recognizing, or capable of binding to, or binding to, or being directed to, or being designed to bind to an insect-specific structure in and/or on a target insect, and at least one other affinity molecule capable of binding to, or binding to, or being directed to, or being designed to bind to an insecticidal protein (toxin) wherein the at least two affinity molecules are operably coupled. Presented herein are also methods of making and using these affinity constructs.Type: ApplicationFiled: February 25, 2022Publication date: April 11, 2024Inventors: Heba Mohamed Yassen ABDELGAFFAR, Constanze HAHNFELD, Juan Luis JURAT-FUENTES, Erik JONGEDIJK, JEFFREY M. STAUB, Stefan MELDAU
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Publication number: 20240041049Abstract: Affinity constructs and affinity molecules to direct insecticidal toxins to insect specific structures of target insects are presented herein. The affinity constructs comprise of at least one affinity molecule that is capable of recognizing, or capable of binding to, or binding to, or being directed to, or being designed to bind to an insect-specific structure in and/or on a target insect, and at least one other affinity molecule capable of binding to, or binding to, or being directed to, or being designed to bind to an insecticidal protein (toxin) wherein the at least two affinity molecules are operably coupled. Presented herein are also methods of making and using these affinity constructs and affinity molecules.Type: ApplicationFiled: July 3, 2023Publication date: February 8, 2024Inventors: Heba Mohamed Yassen ABDELGAFFAR, Constanze HAHNFELD, Juan Luis JURAT-FUENTES, Erik JONGEDIJK, JEFFREY M. STAUB, Stefan MELDAU
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Patent number: 10913939Abstract: The disclosure provides nucleic acid constructs encoding novel chimeric peptides that are useful for nuclear and chloroplast expression of active nitrogenase components including dinitrogenase reductase and dinitrogenase, in plant cells. The disclosure thus provides nucleic acid constructs encoding the chimeric proteins, as well as plant expression constructs comprising the same for expression and/or targeting to the nucleus, plastids, or mitochondria of plant cells. The disclosure also provides methods of use for the novel chimeric peptides that function to provide active dinitrogenase reductase, dinitrogenase, and thus nitrogenase, expressed in plant cells, and plants comprising such nucleic acid constructs.Type: GrantFiled: March 24, 2016Date of Patent: February 9, 2021Assignee: Monsanto Technology LLCInventors: William P. Donovan, Natalia Ivleva, Jeffrey M. Staub
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Publication number: 20190040401Abstract: A method is provided for transforming monocotyledonous plants to express DNA sequences of interest from plant cell plastids. The method allows the transformation of monocot plant tissue with heterologous DNA constructs. The invention also provides for monocot cells in which the plastids contain heterologous DNA constructs.Type: ApplicationFiled: October 18, 2018Publication date: February 7, 2019Inventors: Vladimir Sidorov, Jeffrey M. Staub, Yuechun Wan, Guangning Ye
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Publication number: 20170314032Abstract: A method is provided for transforming monocotyledonous plants to express DNA sequences of interest from plant cell plastids. The method allows the transformation of monocot plant tissue with heterologous DNA constructs. The invention also provides for monocot cells in which the plastids contain heterologous DNA constructs.Type: ApplicationFiled: June 9, 2017Publication date: November 2, 2017Inventors: Vladimir Sidorov, Jeffrey M. Staub, Yuechun Wan, Guangning Ye
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Publication number: 20170233755Abstract: This disclosure provides transgenic plants having enhanced traits such as increased yield, increased nitrogen use efficiency and enhanced drought tolerance; propagules, progeny and field crops of such transgenic plants; and methods of making and using such transgenic plants. This disclosure also provides methods of producing hybrid seed from such transgenic plants, growing such seed and selecting progeny plants with enhanced traits. Also disclosed are transgenic plants with altered phenotypes which are useful for screening and selecting transgenic events for the desired enhanced trait.Type: ApplicationFiled: April 28, 2017Publication date: August 17, 2017Applicant: Monsanto Technology LLCInventors: Mark Scott ABAD, Pranesh BADAMI, Amarjit BASRA, Erin BELL, Christopher P. BONIN, Paolo CASTIGLIONI, R. Eric CERNY, Jaishree M. CHITTOOR, Paul CHOMET, Todd DEZWAAN, Stephen DUFF, Michael D. EDGERTON, Barry S. GOLDMAN, Balasulojini KARUNANANDAA, Kempagangaiah KRISHNAMURTHY, Ping LI, Adrian A. LUND, Linda LUTFIYYA, Thomas M. MALVAR, Donald E. NELSON, Monnanda S. RAJANI, Dhanalakshmi RAMACHANDRA, Thomas G. RUFF, Sara SALVADOR, S. SANGEETHA, Char SHOBHA, Jeffrey M. STAUB, Virginia URSIN, Tyamagondlu V. VENKATESH, Kammaradi R. VIDYA, Xiaoyun WU, Sean YANG, Jianmin ZHAO
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Patent number: 9701973Abstract: A method is provided for transforming monocotyledonous plants to express DNA sequences of interest from plant cell plastids. The method allows the transformation of monocot plant tissue with heterologous DNA constructs. The invention also provides for monocot cells in which the plastids contain heterologous DNA constructs.Type: GrantFiled: January 6, 2016Date of Patent: July 11, 2017Assignee: Monsanto Technology LLCInventors: Vladimir Sidorov, Jeffrey M. Staub, Yuechun Wan, Guangning Ye
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Publication number: 20160304842Abstract: The disclosure provides nucleic acid constructs encoding novel chimeric peptides that are useful for nuclear and chloroplast expression of active nitrogenase components including dinitrogenase reductase and dinitrogenase, in plant cells. The disclosure thus provides nucleic acid constructs encoding the chimeric proteins, as well as plant expression constructs comprising the same for expression and/or targeting to the nucleus, plastids, or mitochondria of plant cells. The disclosure also provides methods of use for the novel chimeric peptides that function to provide active dinitrogenase reductase, dinitrogenase, and thus nitrogenase, expressed in plant cells, and plants comprising such nucleic acid constructs.Type: ApplicationFiled: March 24, 2016Publication date: October 20, 2016Inventors: William P. Donovan, Natalia lvleva, Jeffrey M. Staub
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Publication number: 20160186193Abstract: A method is provided for transforming monocotyledonous plants to express DNA sequences of interest from plant cell plastids. The method allows the transformation of monocot plant tissue with heterologous DNA constructs. The invention also provides for monocot cells in which the plastids contain heterologous DNA constructs.Type: ApplicationFiled: January 6, 2016Publication date: June 30, 2016Inventors: Vladimir Sidorov, Jeffrey M. Staub, Yuechun Wan, Guangning Ye
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Patent number: 9267144Abstract: A method is provided for transforming maize plants to express DNA sequences of interest from plant cell plastids. The method allows the transformation of maize plant tissue with heterologous DNA constructs by microprojectile bombardment of green light grown cultures and dark grown embryogenic cultures. The invention also provides for maize cells in which the plastids contain heterologous DNA constructs.Type: GrantFiled: April 18, 2008Date of Patent: February 23, 2016Assignee: Monsanto Technology LLCInventors: Vladimir Sidorov, Jeffrey M. Staub, Yuechun Wan, Guangning Ye
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Publication number: 20150089683Abstract: This disclosure provides transgenic plants having enhanced traits such as increased yield, increased nitrogen use efficiency and enhanced drought tolerance; propagules, progeny and field crops of such transgenic plants; and methods of making and using such transgenic plants. This disclosure also provides methods of producing hybrid seed from such transgenic plants, growing such seed and selecting progeny plants with enhanced traits. Also disclosed are transgenic plants with altered phenotypes which are useful for screening and selecting transgenic events for the desired enhanced trait.Type: ApplicationFiled: March 6, 2013Publication date: March 26, 2015Inventors: Mark Scott Abad, Pranesh Badami, Amarjit Basra, Erin Bell, Christopher P. Bonin, Paolo Castiglioni, Eric R. Cerny, Jaishree M. Chittoor-Vijayanath, Paul Chomet, Todd Dezwaan, Stephen Duff, Michael D. Edgerton, Barry S. Goldman, Balasulojini Karunanandaa, Kempagangaiah Krishnamurthy, Ping Li, Adrian A. Lund, Llinda Lutfiyya, Thomas M. Malvar, Donald E. Nelson, Monnanda S. Rajani, Dhanalakshmi Ramachandra, Thomas G. Ruff, Sara Salvador, S. Sangeetha, Char Shobha, Jeffrey M. Staub, Virginia Ursin, Tyamagondlu V. Venkatesh, Kammaradi R. Vidya, Xiaoyun Wu, Sean Yang, Jianmin Zhao
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Patent number: 8404927Abstract: This invention discloses recombinant DNA constructs that transcribe to RNA having improved resistance to a plant RNase III enzyme, and methods for their use in making transgenic plant cells, plants, seeds, and products derived therefrom. Also provided are compositions and methods for imparting to a plant resistance to a pest or pathogen of the plant.Type: GrantFiled: June 13, 2006Date of Patent: March 26, 2013Assignee: Monsanto Technology LLCInventors: Edwards Allen, Larry A. Gilbertson, Elysia K. Krieger, James K. Roberts, Jeffrey M. Staub
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Publication number: 20120210458Abstract: This disclosure provides purified nucleic acids and polypeptides and various uses of these sequences such as transcript profiling. Also provided are transgenic plants, seeds, and plant cells containing DNA for expression of the proteins that are useful for imparting enhanced agronomic trait(s) to transgenic crop plants, methods of making such plants and methods of making agricultural commodity including seeds and hybrid seeds from such plants.Type: ApplicationFiled: February 23, 2010Publication date: August 16, 2012Inventors: Yongwei Cao, Jeffrey M. Staub, Bo-Xing Qiu, James A. Morrell, Wei Wu
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Publication number: 20120117685Abstract: This disclosure provides purified nucleic acids and polypeptides and various uses of these sequences such as transcript profiling. Also provided are transgenic plants, seeds, and plant cells containing DNA for expression of the proteins that are useful for imparting enhanced agronomic trait(s) to transgenic crop plants, methods of making such plants and methods of making agricultural commodity including seeds and hybrid seeds from such plants.Type: ApplicationFiled: February 23, 2010Publication date: May 10, 2012Inventors: Wei Wu, Jeffrey M. Staub, James A. Morrell, Bo-Xing Qiu, YongWei Cao
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Publication number: 20120023611Abstract: This disclosure provides purified nucleic acids and polypeptides and various uses of these sequences such as transcript profiling. Also provided are transgenic plants, seeds, and plant cells containing DNA for expression of the proteins that are useful for imparting enhanced agronomic trait(s) to transgenic crop plants, methods of making such plants and methods of making agricultural commodity including seeds and hybrid seeds from such plants.Type: ApplicationFiled: February 23, 2010Publication date: January 26, 2012Inventors: Yongwei Cao, Jeffrey M. Staub, Bo-Xing Qiu, James A. Morrell, Wei Wu
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Patent number: 7732662Abstract: Novel compositions and methods useful for genetic engineering of plant cells to provide a method of producing plastid transformed plants are provided in the instant invention. In particular, the present invention provides methods for obtaining plastid transformed plants on medium containing plastid lethal compounds.Type: GrantFiled: August 6, 2007Date of Patent: June 8, 2010Assignee: Monsanto Technology LLCInventors: Jeffrey M Staub, Guangning Ye, Debra L. Broyles
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Publication number: 20080289063Abstract: A method is provided for transforming maize plants to express DNA sequences of interest from plant cell plastids. The method allows the transformation of maize plant tissue with heterologous DNA constructs by microprojectile bombardment of green light grown cultures and dark grown embryogenic cultures. The invention also provides for maize cells in which the plastids contain heterologous DNA constructs.Type: ApplicationFiled: April 18, 2008Publication date: November 20, 2008Applicant: MONSANTO TECHNOLOGY LLCInventors: Vladimir Sidorov, Jeffrey M. Staub, Yuechun Wan, Guangning Ye
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Patent number: 7259293Abstract: Constructs and methods are provided for expressing peptides derived from eukaryotic organisms in plant plastids. Constructs have a promoter functional in a plant plastid, a DNA sequence encoding a peptide derived from an eukaryotic organism and a transcription termination region. Other elements include a selectable marker for selection of plant cells comprising a plastid expressing the marker and DNA regions of homology to the genome of the plastid and optionally a ribosome binding site joined to the promoter. By methods using such constructs high levels of eukaryotic peptides, such as mammalian proteins, are produced in a plant cell by growing plant cells under conditions whereby the DNA encoding sequences are expressed to produce eukaryotic peptide in said plastid.Type: GrantFiled: August 13, 2004Date of Patent: August 21, 2007Assignee: Calgene LLCInventor: Jeffrey M. Staub
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Patent number: 6849778Abstract: Novel compositions and methods useful for genetic engineering of plant cells are provided. In particular, plastid constructs comprising recombining sites are provided. Such constructs find use in methods for site specific recombination in plant cell plastids. Plant cells and plants comprising the constructs described herein, as well as plant cells and plants produced by the methods of the present invention are of interest.Type: GrantFiled: October 16, 2000Date of Patent: February 1, 2005Assignee: Calgene LLCInventors: Jeffrey M. Staub, Peter H. J. Hajdukiewicz, Larry Gilbertson
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Patent number: 6812379Abstract: Constructs and methods are provided for expressing peptides derived from eukaryotic organisms in plant plastids. Constructs have a promoter functional in a plant plastid, a DNA sequence encoding a peptide derived from an eukaryotic organism and a transcription termination region. Other elements include a selectable marker for selection of plant cells comprising a plastid expressing the marker and DNA regions of homology to the genome of the plastid and optionally a ribosome binding site joined to the promoter. By methods using such constructs high levels of eukaryotic peptides, such as mammalian proteins, are produced in a plant cell by growing plant cells under conditions whereby the DNA encoding sequences are expressed to produce eukaryotic peptide in said plastid.Type: GrantFiled: March 20, 2002Date of Patent: November 2, 2004Assignee: Calgene LLCInventor: Jeffrey M. Staub